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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+13.19%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$12.1B
AUM Growth
+$1.25B
Cap. Flow
-$1.53B
Cap. Flow %
-12.71%
Top 10 Hldgs %
75.84%
Holding
141
New
6
Increased
25
Reduced
5
Closed
8

Top Buys

Rank Stock Value
1
ACOR
Acorda Therapeutics
ACOR
+$90.4M
2
SGEN
Seagen Inc. Common Stock
SGEN
+$52.6M
3
DYAX
DYAX CORPORATION
DYAX
+$24.1M
4
ALKS icon
Alkermes
ALKS
+$17.5M
5
AAAP
Advanced Accelerator Applications S.A.
AAAP
+$15.8M

Top Sells

Rank Stock Value
1
CLVS
Clovis Oncology, Inc.
CLVS
+$18.6M
2
XNPT
XENOPORT, INC.
XNPT
+$17M
3
ALDR
Alder Biopharmaceuticals
ALDR
+$16.8M
4
RPRX
Repros Therapeutics Inc.
RPRX
+$14.5M
5
LRMR icon
Larimar Therapeutics
LRMR
+$12.5M

Sector Composition

Rank Sector Weight
1 Healthcare 78.52%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MDVN
26
DELISTED
MEDIVATION, INC.
MDVN
$31.9M 0.26%
659,752
– –
PGNX
27
DELISTED
Progenics Pharmaceuticals Inc
PGNX
$26.7M 0.22%
4,350,808
– –
GILD icon
28
Gilead Sciences
GILD
$181B
$25.3M 0.21%
249,995
– –
TGTX icon
29
TG Therapeutics
TGTX
$8.31B
$23.9M 0.2%
2,003,991
– –
LKFT
30
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.89B
$23.2M 0.19%
369,276
– –
ATYR
31
aTyr Pharma
ATYR
$49.2M
$23M 0.19%
166,795
– –
ACHN
32
DELISTED
Achillion Pharmaceuticals
ACHN
$21.6M 0.18%
2,000,000
– –
ACGN
33
DELISTED
Aceragen Inc
ACGN
$21.6M 0.18%
51,398
+51
+0.1% +$22.8K
CPRX
34
DELISTED
Catalyst Pharmaceutical
CPRX
$20.3M 0.17%
8,275,630
+939,938
+13% +$2.69M
ALKS icon
35
Alkermes
ALKS
$8.11B
$19.9M 0.16%
+250,251
New +$17.5M
XNPT
36
DELISTED
XENOPORT, INC.
XNPT
$19.1M 0.16%
3,475,672
-3,032,950
-47% -$17M
NVAX icon
37
Novavax
NVAX
$1.47B
$18.4M 0.15%
109,784
– –
ARRY
38
DELISTED
Array Biopharma Inc
ARRY
$18.2M 0.15%
4,310,666
– –
INSM icon
39
Insmed
INSM
$27.5B
$18.1M 0.15%
1,000,000
-583,490
-37% -$10.3M
AAAP
40
DELISTED
Advanced Accelerator Applications S.A.
AAAP
$17.7M 0.15%
+567,454
New +$15.8M
DSCI
41
DELISTED
Derma Sciences, Inc. Common Stock (DE)
DSCI
$17.1M 0.14%
3,752,390
+294,549
+9% +$1.4M
FOMX
42
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
$16.6M 0.14%
2,046,967
– –
ZGNX
43
DELISTED
Zogenix, Inc.
ZGNX
$14.7M 0.12%
1,000,000
-798,365
-44% -$10.7M
ARCT icon
44
Arcturus Therapeutics
ARCT
$382M
$14.7M 0.12%
333,766
+99,499
+42% +$4.48M
IOVA icon
45
Iovance Biotherapeutics
IOVA
$3.76B
$14M 0.12%
1,817,429
– –
DMTX
46
DELISTED
Dimension Therapeutics, Inc
DMTX
$13.9M 0.12%
+1,234,481
New +$15.6M
RARE icon
47
Ultragenyx Pharmaceutical
RARE
$2.55B
$13.9M 0.12%
123,894
– –
GBT
48
DELISTED
Global Blood Therapeutics, Inc.
GBT
$12.9M 0.11%
400,000
+200,000
+100% +$8.66M
XNCR icon
49
Xencor
XNCR
$2.07B
$12.8M 0.11%
872,072
– –
MGNX icon
50
MacroGenics
MGNX
$261M
$11.3M 0.09%
363,676
+15,900
+5% +$483K
1
2
3 4 5

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Julian Baker's Q4 2015 Portfolio in Review

As of Q4 2015, Julian Baker held 141 positions worth $12.1B, up 12% from $10.8B the previous quarter. Its ten largest holdings account for 76% of the portfolio.

Julian Baker withdrew a net $1.53B in Q4 2015, closing 8 positions and reducing 5 holdings. Its most notable exit was Clovis Oncology, Inc., an estimated $18.6M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 79% of assets, up from 78% a quarter earlier, followed by Technology.

Against the trend, Julian Baker opened a new position in Alkermes worth $19.9M.

  • Julian Baker's largest Q4 2015 buy was Alkermes: 250,251 shares worth $19.9M.
  • Julian Baker added most to Acorda Therapeutics in Q4 2015, an estimated $90.4M increase.
  • Julian Baker's biggest Q4 2015 reduction was XENOPORT, INC., cutting an estimated $17M.
  • Julian Baker fully exited Clovis Oncology, Inc. in Q4 2015, selling an estimated $18.6M.
  • Julian Baker's ten largest holdings make up 76% of its $12.1B portfolio in Q4 2015.
  • Julian Baker opened 6 new positions and closed 8 in Q4 2015.
  • Julian Baker's portfolio value rose 12% quarter-over-quarter to $12.1B.

Based on Baker Bros. Advisors's 13F filing for Q4 2015, filed 16 Feb 2016.