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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
-6.24%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$10.8B
AUM Growth
-$577M
Cap. Flow
-$347M
Cap. Flow %
-3.21%
Top 10 Hldgs %
77.46%
Holding
139
New
12
Increased
27
Reduced
8
Closed
6

Top Buys

Rank Stock Value
1
INCY icon
Incyte
INCY
+$517M
2
SGEN
Seagen Inc. Common Stock
SGEN
+$232M
3
DBVT
DBV Technologies
DBVT
+$142M
4
ANAC
ANACOR PHARMACEUTICALS INC COM
ANAC
+$66.6M
5
NGNE icon
Neurogene
NGNE
+$63.9M

Top Sells

Rank Stock Value
1
XOMA
Xoma
XOMA
+$57M
2
KYTH
KYTHERA BIOPHARMACEUTICALS, INC COM
KYTH
+$29.2M
3
ALDR
Alder Biopharmaceuticals
ALDR
+$16.1M
4
OMER icon
Omeros
OMER
+$9.78M
5
DYAX
DYAX CORPORATION
DYAX
+$8.72M

Sector Composition

Rank Sector Weight
1 Healthcare 77.98%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
PGNX
26
DELISTED
Progenics Pharmaceuticals Inc
PGNX
$24.9M 0.23%
4,350,808
– –
GILD icon
27
Gilead Sciences
GILD
$181B
$24.5M 0.23%
249,995
– –
ITCI
28
DELISTED
Intra-Cellular Therapies Inc.
ITCI
$24.4M 0.23%
609,166
+505,000
+485% +$16.5M
ZGNX
29
DELISTED
Zogenix, Inc.
ZGNX
$24.3M 0.22%
1,798,365
+544,794
+43% +$9.83M
ATYR
30
aTyr Pharma
ATYR
$49.2M
$24M 0.22%
166,795
– –
ACGN
31
DELISTED
Aceragen Inc
ACGN
$23.4M 0.22%
51,347
+39
+0.1% +$17.2K
XNPT
32
DELISTED
XENOPORT, INC.
XNPT
$22.6M 0.21%
6,508,622
– –
CPRX
33
DELISTED
Catalyst Pharmaceutical
CPRX
$22M 0.2%
7,335,692
– –
SGMO
34
DELISTED
SANGAMO THERAPEUTICS INC
SGMO
$21.2M 0.2%
3,755,876
+524,944
+16% +$4.33M
TGTX icon
35
TG Therapeutics
TGTX
$8.31B
$20.2M 0.19%
2,003,991
– –
ARRY
36
DELISTED
Array Biopharma Inc
ARRY
$19.7M 0.18%
4,310,666
-1,171,839
-21% -$6.95M
CLVS
37
DELISTED
Clovis Oncology, Inc.
CLVS
$18.6M 0.17%
202,630
– –
ALDR
38
DELISTED
Alder Biopharmaceuticals
ALDR
$16.8M 0.16%
513,439
-378,249
-42% -$16.1M
DSCI
39
DELISTED
Derma Sciences, Inc. Common Stock (DE)
DSCI
$16.3M 0.15%
3,457,841
– –
NVAX icon
40
Novavax
NVAX
$1.47B
$15.5M 0.14%
109,784
+12,500
+13% +$2.8M
LKFT
41
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.89B
$15M 0.14%
369,276
– –
FOMX
42
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
$15M 0.14%
2,046,967
– –
RPRX
43
DELISTED
Repros Therapeutics Inc.
RPRX
$14.5M 0.13%
1,955,944
– –
PRQR icon
44
ProQR Therapeutics
PRQR
$330M
$14.4M 0.13%
988,299
– –
ACHN
45
DELISTED
Achillion Pharmaceuticals
ACHN
$13.8M 0.13%
2,000,000
+476,261
+31% +$3.88M
LRMR icon
46
Larimar Therapeutics
LRMR
$434M
$12.5M 0.12%
32,529
+8,556
+36% +$3.86M
BLUE
47
DELISTED
bluebird bio
BLUE
$12.1M 0.11%
10,893
-772
-7% -$1.41M
RARE icon
48
Ultragenyx Pharmaceutical
RARE
$2.55B
$11.9M 0.11%
123,894
– –
MTEM
49
DELISTED
Molecular Templates, Inc.
MTEM
$11.9M 0.11%
17,730
– –
LJPC
50
DELISTED
La Jolla Pharmaceutical Company
LJPC
$11.4M 0.11%
412,008
– –
1
2
3 4 5

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Julian Baker's Q3 2015 Portfolio in Review

As of Q3 2015, Julian Baker held 139 positions worth $10.8B, down 5.1% from $11.4B the previous quarter. Its ten largest holdings account for 77% of the portfolio.

Julian Baker withdrew a net $347M in Q3 2015, closing 6 positions and reducing 8 holdings. Its most notable exit was Xoma, an estimated $57M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 78% of assets, up from 78% a quarter earlier, followed by Technology.

Against the trend, Julian Baker opened a new position in MEDIVATION, INC. worth $28M.

  • Julian Baker's largest Q3 2015 buy was MEDIVATION, INC.: 659,752 shares worth $28M.
  • Julian Baker added most to Incyte in Q3 2015, an estimated $517M increase.
  • Julian Baker's biggest Q3 2015 reduction was Alder Biopharmaceuticals, cutting an estimated $16.1M.
  • Julian Baker fully exited Xoma in Q3 2015, selling an estimated $57M.
  • Julian Baker's ten largest holdings make up 77% of its $10.8B portfolio in Q3 2015.
  • Julian Baker opened 12 new positions and closed 6 in Q3 2015.
  • Julian Baker's portfolio value fell 5.1% quarter-over-quarter to $10.8B.

Based on Baker Bros. Advisors's 13F filing for Q3 2015, filed 16 Nov 2015.