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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+1.74%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$7.1B
AUM Growth
+$59.7M
Cap. Flow
-$1.53B
Cap. Flow %
-21.52%
Top 10 Hldgs %
75.68%
Holding
101
New
15
Increased
16
Reduced
17
Closed
6

Top Buys

Rank Stock Value
1
BMRN icon
BioMarin Pharmaceuticals
BMRN
+$78.6M
2
SGEN
Seagen Inc. Common Stock
SGEN
+$57.7M
3
ANAC
ANACOR PHARMACEUTICALS INC COM
ANAC
+$22.5M
4
DYAX
DYAX CORPORATION
DYAX
+$15.4M
5
QCOR
QUESTCOR PHARMA INC
QCOR
+$13.6M

Top Sells

Rank Stock Value
1
VPHM
VIROPHARMA INC
VPHM
+$220M
2
GILD icon
Gilead Sciences
GILD
+$48M
3
PCYC
PHARMACYCLICS INC
PCYC
+$35.3M
4
ARIA
Ariad Pharmaceuticals Inc
ARIA
+$24.5M
5
AEGR
Aegerion Pharmaceuticals
AEGR
+$24.5M

Sector Composition

Rank Sector Weight
1 Healthcare 50.41%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
AVNR
26
DELISTED
AVANIR PHARMACEUTICALS, INC CL A
AVNR
$18.2M 0.26%
5,428,591
+1,000,000
+23% +$4.13M
DYAX
27
DELISTED
DYAX CORPORATION
DYAX
$15.3M 0.22%
+2,026,537
New +$15.4M
ACGN
28
DELISTED
Aceragen Inc
ACGN
$14.7M 0.21%
23,345
-19,823
-46% -$6.61M
SGYP
29
DELISTED
Synergy Pharmaceuticals, Inc Common Stock
SGYP
$14.7M 0.21%
2,644,787
– –
INSM icon
30
Insmed
INSM
$27.5B
$13.5M 0.19%
796,378
-149,425
-16% -$2.29M
STML
31
DELISTED
Stemline Therapeutics, Inc.
STML
$13.2M 0.19%
675,042
-125,358
-16% -$3.35M
KYTH
32
DELISTED
KYTHERA BIOPHARMACEUTICALS, INC COM
KYTH
$11.7M 0.16%
313,191
+48,191
+18% +$2M
IONS icon
33
Ionis Pharmaceuticals
IONS
$9.93B
$9.84M 0.14%
247,036
– –
ZGNX
34
DELISTED
Zogenix, Inc.
ZGNX
$9.46M 0.13%
343,875
+93,750
+37% +$2.1M
PRTA icon
35
Prothena Corp
PRTA
$485M
$8.94M 0.13%
336,918
-32,732
-9% -$821K
MTEM
36
DELISTED
Molecular Templates, Inc.
MTEM
$8.65M 0.12%
11,227
– –
TGTX icon
37
TG Therapeutics
TGTX
$8.31B
$8.58M 0.12%
2,199,656
+1,599,656
+267% +$6.46M
QLTI
38
DELISTED
QLT Inc
QLTI
$8.55M 0.12%
1,535,863
– –
WINT
39
DELISTED
Windtree Therapeutics Inc
WINT
$8.37M 0.12%
265,616
+157,143
+145% +$4.91M
ARRY
40
DELISTED
Array Biopharma Inc
ARRY
$7.51M 0.11%
1,500,000
– –
AMBI
41
DELISTED
Ambit Biosciences Corp
AMBI
$7.21M 0.1%
747,954
-8
-0% -$107
OMER icon
42
Omeros
OMER
$1.39B
$6.87M 0.1%
608,404
– –
NVAX icon
43
Novavax
NVAX
$1.47B
$6.59M 0.09%
64,346
-21,500
-25% -$1.52M
IRWD icon
44
Ironwood Pharmaceuticals
IRWD
$709M
$6.34M 0.09%
652,115
+101,490
+18% +$911K
OSIR
45
DELISTED
Osiris Therapeutics, Inc. Common Stock
OSIR
$6.04M 0.09%
375,282
– –
XNPT
46
DELISTED
XENOPORT, INC.
XNPT
$5.95M 0.08%
1,034,112
– –
SGMO
47
DELISTED
SANGAMO THERAPEUTICS INC
SGMO
$5.89M 0.08%
424,308
+247,601
+140% +$2.85M
PTLA
48
DELISTED
Portola Pharmaceuticals, Inc.
PTLA
$5.78M 0.08%
224,434
-75,477
-25% -$1.83M
AERI
49
DELISTED
Aerie Pharmaceuticals
AERI
$5.39M 0.08%
+300,000
New +$3.91M
XNCR icon
50
Xencor
XNCR
$2.07B
$5.03M 0.07%
+550,000
New +$4.72M
1
2
3 4

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Julian Baker's Q4 2013 Portfolio in Review

As of Q4 2013, Julian Baker held 101 positions worth $7.1B, up 0.85% from $7.04B the previous quarter. Its ten largest holdings account for 76% of the portfolio.

Julian Baker withdrew a net $1.53B in Q4 2013, closing 6 positions and reducing 17 holdings. Its most notable exit was VIROPHARMA INC, an estimated $220M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 50% of assets, up from 48% a quarter earlier.

Against the trend, Julian Baker opened a new position in DYAX CORPORATION worth $15.3M.

  • Julian Baker's largest Q4 2013 buy was DYAX CORPORATION: 2,026,537 shares worth $15.3M.
  • Julian Baker added most to BioMarin Pharmaceuticals in Q4 2013, an estimated $78.6M increase.
  • Julian Baker's biggest Q4 2013 reduction was Gilead Sciences, cutting an estimated $48M.
  • Julian Baker fully exited VIROPHARMA INC in Q4 2013, selling an estimated $220M.
  • Julian Baker's ten largest holdings make up 76% of its $7.1B portfolio in Q4 2013.
  • Julian Baker opened 15 new positions and closed 6 in Q4 2013.
  • Julian Baker's portfolio value rose 0.85% quarter-over-quarter to $7.1B.

Based on Baker Bros. Advisors's 13F filing for Q4 2013, filed 14 Feb 2014.