John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street Financial Select Sector SPDR ETF
XLF
|
+$474M |
| 2 |
State Street Consumer Staples Select Sector SPDR ETF
XLP
|
+$357M |
| 3 |
Accenture
ACN
|
+$246M |
| 4 |
Advanced Micro Devices
AMD
|
+$235M |
| 5 |
State Street SPDR Dow Jones Industrial Average ETF Trust
DIA
|
+$231M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Invesco QQQ Trust
QQQ
|
+$381M |
| 2 |
State Street Technology Select Sector SPDR ETF
XLK
|
+$375M |
| 3 |
iShares Expanded Tech-Software Sector ETF
IGV
|
+$348M |
| 4 |
Thermo Fisher Scientific
TMO
|
+$292M |
| 5 |
Snowflake
SNOW
|
+$258M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 16.18% |
| 2 | Financials | 15.54% |
| 3 | Industrials | 10.5% |
| 4 | Healthcare | 9.8% |
| 5 | Consumer Discretionary | 8.1% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
|
EONR
3401
EON Resources
EONR
$24.1M
| $94.9K | ﹤0.01% |
194,560
+165,709
| +574% | +$60.2K |
|
3402
AEye
LIDR
$56.3M
| $94.7K | ﹤0.01% |
+38,012
| New | +$91.1K |
|
|
LAC
3403
Lithium Americas
LAC
$1.13B
| $93.4K | ﹤0.01% |
16,357
-150,279
| -90% | -$475K |
|
3404
Spero Therapeutics
SPRO
$71M
| $92.9K | ﹤0.01% |
+49,399
| New | +$109K |
|
3405
inTEST
INTT
$145M
| $92.7K | ﹤0.01% |
11,867
-1,176
| -9% | -$8.63K |
|
|
KZR
3406
DELISTED
Kezar Life Sciences
KZR
| $92.4K | ﹤0.01% |
23,682
-1,201
| -5% | -$4.92K |
|
|
GXAI
3407
Gaxos.ai
GXAI
$11.6M
| $90.2K | ﹤0.01% |
+56,745
| New | +$84K |
|
3408
Imperial Petroleum
IMPP
$239M
| $89.9K | ﹤0.01% |
+18,803
| New | +$66.1K |
|
3409
Indonesia Energy Corp
INDO
$44.3M
| $89.7K | ﹤0.01% |
29,892
+4,550
| +18% | +$13.2K |
|
|
DDL
3410
Dingdong
DDL
$514M
| $89.4K | ﹤0.01% |
+43,200
| New | +$93.6K |
|
3411
BTCS Inc
BTCS
$73.7M
| $87.4K | ﹤0.01% |
18,100
-11,508
| -39% | -$52.7K |
|
3412
Protara Therapeutics
TARA
$229M
| $85.1K | ﹤0.01% |
19,558
+5,154
| +36% | +$16.7K |
|
3413
Castellum
CTM
$57.5M
| $84.5K | ﹤0.01% |
77,565
+44,569
| +135% | +$51.8K |
|
3414
AquaBounty Technologies
AQB
$6.74M
| $84.1K | ﹤0.01% |
+37,565
| New | +$37.1K |
|
|
TSE
3415
DELISTED
Trinseo
TSE
| $83.9K | ﹤0.01% |
35,714
-99,421
| -74% | -$259K |
|
|
INN
3416
Summit Hotel Properties
INN
$664M
| $80.2K | ﹤0.01% |
14,607
-33,840
| -70% | -$185K |
|
3417
Sensus Healthcare
SRTS
$56.3M
| $79.8K | ﹤0.01% |
25,407
-20,519
| -45% | -$80.5K |
|
3418
Ainos
AIMD
$10.2M
| $79.7K | ﹤0.01% |
+23,008
| New | +$74.7K |
|
|
INTZ
3419
Intrusion
INTZ
$15.5M
| $79.3K | ﹤0.01% |
49,584
-13,321
| -21% | -$25.2K |
|
|
DVS
3420
DELISTED
Dolly Varden Silver Corp
DVS
| $79.3K | ﹤0.01% |
+15,828
| New | +$60.9K |
|
3421
Hyliion Holdings
HYLN
$563M
| $79.1K | ﹤0.01% |
+40,165
| New | +$66.9K |
|
3422
Westrock Coffee
WEST
$816M
| $77.7K | ﹤0.01% |
+15,994
| New | +$96.2K |
|
3423
Mizuho Financial
MFG
$124B
| $77.5K | ﹤0.01% |
11,569
-23,800
| -67% | -$148K |
|
|
API
3424
Agora
API
$359M
| $76.4K | ﹤0.01% |
20,000
-30,587
| -60% | -$115K |
|
|
GBIO
3425
DELISTED
Generation Bio
GBIO
| $76.1K | ﹤0.01% |
12,442
+1,846
| +17% | +$9.56K |
|
Similar funds
John Overdeck's Q3 2025 Portfolio in Review
As of Q3 2025, John Overdeck held 4,027 positions worth $67.2B, up 19% from $56.5B the previous quarter. Its ten largest holdings account for 6.2% of the portfolio.
John Overdeck deployed $4.46B of net new capital in Q3 2025, opening 877 new positions and adding to 1,461 existing holdings. Its largest new stake was Berkshire Hathaway Class B: 379,096 shares worth $191M.
By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 17% a quarter earlier, followed by Financials and Industrials.
On the sell side, the largest reduction was Invesco QQQ Trust, an estimated $381M trimmed.
- John Overdeck's largest Q3 2025 buy was Berkshire Hathaway Class B: 379,096 shares worth $191M.
- John Overdeck added most to State Street Financial Select Sector SPDR ETF in Q3 2025, an estimated $474M increase.
- John Overdeck's biggest Q3 2025 reduction was Invesco QQQ Trust, cutting an estimated $381M.
- John Overdeck fully exited NextEra Energy, Inc. 6.926% Corporate Units in Q3 2025, selling an estimated $115M.
- John Overdeck's ten largest holdings make up 6.2% of its $67.2B portfolio in Q3 2025.
- John Overdeck opened 877 new positions and closed 399 in Q3 2025.
- John Overdeck's portfolio value rose 19% quarter-over-quarter to $67.2B.
Based on Two Sigma Investments's 13F filing for Q3 2025, filed 14 Nov 2025.