Jane Street
SLNO

Jane Street’s Soleno Therapeutics SLNO Stock Holding History

Jane Street’s Portfolio SLNO Stock Details SLNO Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$2.43M Buy
72,500
+36,300
+100% +$1.42M ﹤0.01% 4721
2025
Q4 		$1.68M Sell
36,200
-127,600
-78% -$7M ﹤0.01% 5156
2025
Q3 		$11.1M Buy
163,800
+79,400
+94% +$5.89M ﹤0.01% 2294
2025
Q2 		$7.07M Sell
84,400
-44,400
-34% -$3.32M ﹤0.01% 2564
2025
Q1 		$9.2M Sell
128,800
-15,400
-11% -$750K ﹤0.01% 2105
2024
Q4 		$6.48M Buy
144,200
+90,100
+167% +$4.67M ﹤0.01% 2343
2024
Q3 		$2.73M Buy
54,100
+44,800
+482% +$2.14M ﹤0.01% 3891
2024
Q2 		$379K Buy
+9,300
New +$394K ﹤0.01% 7444
2024
Q1 		– Sell
-10,800
Closed -$435K – 10006
2023
Q4 		$435K Buy
+10,800
New +$307K ﹤0.01% 7000

Other funds holding SLNO

Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
NCM
Nantahala Capital Management New Canaan, Connecticut $2.72B AUM 121.58% 1-Year Est. Return
PCH
Polar Capital Holdings London, United Kingdom $28.2B AUM 115.26% 1-Year Est. Return
KCM
Khrom Capital Management Miami Beach, Florida $1.09B AUM 14.82% 1-Year Est. Return

Jane Street's SLNO Position: Q1 2026 in Review

Jane Street reduced its Soleno Therapeutics (SLNO) stake by 92% in Q1 2026, selling an estimated $5.13M and leaving 11,002 shares worth $368K. The position accounts for ﹤0.01% of the portfolio, ranked #8761.

Jane Street first reported a position in SLNO in Q1 2015 and has held it in 13 quarters since. The position peaked at $6.56M in Q4 2025. 225 funds tracked by Wall St. Rank hold SLNO as of Q1 2026.

  • Jane Street held 11,002 shares of Soleno Therapeutics worth $368K as of Q1 2026.
  • Jane Street sold 130,738 Soleno Therapeutics shares in Q1 2026, an estimated $5.13M.
  • Soleno Therapeutics made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #8761 holding.
  • Jane Street first reported a position in Soleno Therapeutics in Q1 2015 and has held it in 13 quarters since.
  • Jane Street's Soleno Therapeutics position peaked at $6.56M in Q4 2025.
  • 225 funds tracked by Wall St. Rank held Soleno Therapeutics as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.