Jane Street
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Jane Street’s Direxion Daily Pharmaceutical & Medical Bull 3X ETF PILL Stock Holding History

Jane Street’s Portfolio PILL Stock Details PILL Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-97,434
Closed -$786K – 12081
2025
Q3 		$786K Buy
+97,434
New +$660K ﹤0.01% 6844
2024
Q4 		– Sell
-47,966
Closed -$393K – 10271
2024
Q3 		$393K Buy
+47,966
New +$361K ﹤0.01% 7593
2024
Q1 		– Sell
-11,682
Closed -$90.5K – 9877
2023
Q4 		$90.5K Buy
+11,682
New +$70.3K ﹤0.01% 8620
2022
Q1 		– Sell
-26,747
Closed -$425K – 10866
2021
Q4 		$425K Buy
+26,747
New +$467K ﹤0.01% 7553
2020
Q2 		– Sell
-27,027
Closed -$267K – 7457
2020
Q1 		$267K Buy
27,027
+16,902
+167% +$349K ﹤0.01% 4333
2019
Q4 		$256K Buy
+10,125
New +$173K ﹤0.01% 4469
2019
Q1 		– Sell
-11,640
Closed -$248K – 5475
2018
Q4 		$248K Sell
11,640
-10,204
-47% -$287K ﹤0.01% 4273
2018
Q3 		$809K Sell
21,844
-3,395
-13% -$117K ﹤0.01% 3030
2018
Q2 		$729K Sell
25,239
-6,700
-21% -$171K ﹤0.01% 3152
2018
Q1 		$754K Buy
31,939
+19,301
+153% +$552K ﹤0.01% 3000
2017
Q4 		$344K Buy
+12,638
New +$332K ﹤0.01% 3612

Other funds holding PILL

Simplex Trading
Simplex Trading Chicago, Illinois $149B AUM 62.07% 1-Year Est. Return
FC
Financial Consulate Hunt Valley, Maryland $899M AUM 20.23% 1-Year Est. Return
TRCT
Tower Research Capital (TRC) New York $3.85B AUM 32.11% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return

Jane Street's PILL Position: Q4 2025 in Review

Jane Street sold out of Direxion Daily Pharmaceutical & Medical Bull 3X ETF (PILL) in Q4 2025, closing a stake of 97,434 shares — an estimated $786K sold.

Jane Street first reported a position in PILL in Q4 2017 and held it in 11 quarters. The position peaked at $809K in Q3 2018. 4 funds tracked by Wall St. Rank hold PILL as of Q4 2025.

  • Jane Street reported no remaining Direxion Daily Pharmaceutical & Medical Bull 3X ETF position as of Q4 2025 after selling out during the quarter.
  • Jane Street sold 97,434 Direxion Daily Pharmaceutical & Medical Bull 3X ETF shares in Q4 2025, an estimated $786K.
  • Jane Street first reported a position in Direxion Daily Pharmaceutical & Medical Bull 3X ETF in Q4 2017 and held it in 11 quarters.
  • Jane Street's Direxion Daily Pharmaceutical & Medical Bull 3X ETF position peaked at $809K in Q3 2018.
  • 4 funds tracked by Wall St. Rank held Direxion Daily Pharmaceutical & Medical Bull 3X ETF as of Q4 2025.

Based on Jane Street's 13F filing for Q4 2025, filed 12 Feb 2026.