Jane Street’s Ironwood Pharmaceuticals IRWD Stock Holding History

Jane Street’s Portfolio IRWD Stock Details IRWD Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$87K	Buy	+24,800	New	+$102K	﹤0.01%	10714
2022 Q3	–	Sell	-13,300	Closed	-$153K	–	10051
2022 Q2	$153K	Sell	13,300 -900	-6%	-$10.6K	﹤0.01%	8398
2022 Q1	$179K	Sell	14,200 -9,900	-41%	-$113K	﹤0.01%	9103
2021 Q4	$281K	Sell	24,100 -17,000	-41%	-$209K	﹤0.01%	8297
2021 Q3	$537K	Sell	41,100 -3,400	-8%	-$43.9K	﹤0.01%	7149
2021 Q2	$573K	Sell	44,500 -21,200	-32%	-$243K	﹤0.01%	6985
2021 Q1	$735K	Buy	+65,700	New	+$694K	﹤0.01%	6065
2020 Q4	–	Sell	-27,000	Closed	-$243K	–	7781
2020 Q3	$243K	Buy	+27,000	New	+$268K	﹤0.01%	6173

Other funds holding IRWD

Armistice Capital New York $5.62B AUM 36.06% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

SCM

Sarissa Capital Management Greenwich, Connecticut $158M AUM 103.7% 1-Year Est. Return

Bank of America Charlotte, North Carolina $1.37T AUM 24.88% 1-Year Est. Return

Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return

AQR Capital Management Greenwich, Connecticut $218B AUM 29.41% 1-Year Est. Return

State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

Acadian Asset Management Boston, Massachusetts $70.5B AUM 36% 1-Year Est. Return

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Jane Street's IRWD Position: Q1 2026 in Review

Jane Street reduced its Ironwood Pharmaceuticals (IRWD) stake by 78% in Q1 2026, selling an estimated $9.01M and leaving 622,247 shares worth $2.18M. The position accounts for ﹤0.01% of the portfolio, ranked #4916.

Jane Street first reported a position in IRWD in Q2 2014 and has held it in 35 quarters since. The position peaked at $20.3M in Q1 2023. 226 funds tracked by Wall St. Rank hold IRWD as of Q1 2026.

Jane Street held 622,247 shares of Ironwood Pharmaceuticals worth $2.18M as of Q1 2026.
Jane Street sold 2,197,315 Ironwood Pharmaceuticals shares in Q1 2026, an estimated $9.01M.
Ironwood Pharmaceuticals made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #4916 holding.
Jane Street first reported a position in Ironwood Pharmaceuticals in Q2 2014 and has held it in 35 quarters since.
Jane Street's Ironwood Pharmaceuticals position peaked at $20.3M in Q1 2023.
226 funds tracked by Wall St. Rank held Ironwood Pharmaceuticals as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.