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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
Cap. Flow
+$25.5M
Cap. Flow %
10.17%
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
Closed
1

Top Buys

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$15.6M
2
MSFT icon
Microsoft
MSFT
+$700K
3
NVDA icon
NVIDIA
NVDA
+$665K
4
AAPL icon
Apple
AAPL
+$653K
5
AMZN icon
Amazon
AMZN
+$403K

Top Sells

Rank Stock Value
1
BIOA
BioAge Labs
BIOA
+$428K

Sector Composition

Rank Sector Weight
1 Technology 1.55%
2 Financials 0.62%
3 Consumer Discretionary 0.47%
4 Communication Services 0.44%
5 Healthcare 0.42%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
REGN icon
176
Regeneron Pharmaceuticals
REGN
$82.2B
$11.6K ﹤0.01%
+22
New +$12.3K
ALL icon
177
Allstate
ALL
$64.7B
$11.5K ﹤0.01%
+57
New +$11.4K
MPC icon
178
Marathon Petroleum
MPC
$97.8B
$11.3K ﹤0.01%
+68
New +$10.2K
AFL icon
179
Aflac
AFL
$60.5B
$11.2K ﹤0.01%
+106
New +$11.1K
AZO icon
180
AutoZone
AZO
$49.7B
$11.1K ﹤0.01%
+3
New +$11.1K
COR icon
181
Cencora
COR
$60B
$11.1K ﹤0.01%
+37
New +$10.7K
WDAY icon
182
Workday
WDAY
$43.3B
$11K ﹤0.01%
+46
New +$11.2K
CTVA icon
183
Corteva
CTVA
$50.4B
$11K ﹤0.01%
+148
New +$9.86K
AIG icon
184
American International
AIG
$39.8B
$11K ﹤0.01%
+128
New +$10.7K
OKE icon
185
Oneok
OKE
$58.3B
$10.9K ﹤0.01%
+134
New +$11.2K
O icon
186
Realty Income
O
$59.2B
$10.9K ﹤0.01%
+189
New +$10.7K
TEL icon
187
TE Connectivity
TEL
$62B
$10.8K ﹤0.01%
+64
New +$9.72K
PCAR icon
188
PACCAR
PCAR
$69B
$10.7K ﹤0.01%
+113
New +$10.4K
FDX icon
189
FedEx
FDX
$77.3B
$10.7K ﹤0.01%
+47
New +$10.3K
BDX icon
190
Becton Dickinson
BDX
$50B
$10.7K ﹤0.01%
+62
New +$11.4K
AMP icon
191
Ameriprise Financial
AMP
$49.9B
$10.7K ﹤0.01%
+20
New +$9.88K
PSX icon
192
Phillips 66
PSX
$90B
$10.6K ﹤0.01%
+89
New +$9.97K
SPG icon
193
Simon Property Group
SPG
$71.4B
$10.6K ﹤0.01%
+66
New +$10.4K
RSG icon
194
Republic Services
RSG
$65.6B
$10.6K ﹤0.01%
+43
New +$10.6K
GM icon
195
General Motors
GM
$76.1B
$10.6K ﹤0.01%
+215
New +$10.2K
URI icon
196
United Rentals
URI
$70.3B
$10.5K ﹤0.01%
+14
New +$9.36K
FAST icon
197
Fastenal
FAST
$59.9B
$10.3K ﹤0.01%
+246
New +$9.98K
SRE icon
198
Sempra
SRE
$56.2B
$10.3K ﹤0.01%
+136
New +$10.1K
KR icon
199
Kroger
KR
$34.3B
$10.3K ﹤0.01%
+143
New +$9.88K
D icon
200
Dominion Energy
D
$59.8B
$10.2K ﹤0.01%
+181
New +$9.92K

Similar funds

Howard Hughes Medical Institute's Q2 2025 Portfolio in Review

As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.

Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.

By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.

On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.

  • Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
  • Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
  • Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
  • Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
  • Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
  • Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.

Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.