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HHMI
Howard Hughes Medical Institute Portfolio holdings
AUM
$416M
1-Year Est. Return
13.82%
This Fund
S&P 500
This Quarter
Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
(+24%)
Cap. Flow
+$25.5M
Cap. Flow
% of AUM
10.17%
Top 10 Holdings %
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$15.6M |
| 2 |
Microsoft
MSFT
|
+$700K |
| 3 |
NVIDIA
NVDA
|
+$665K |
| 4 |
Apple
AAPL
|
+$653K |
| 5 |
Amazon
AMZN
|
+$403K |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
BIOA
BioAge Labs
BIOA
|
+$428K |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 1.55% |
| 2 | Financials | 0.62% |
| 3 | Consumer Discretionary | 0.47% |
| 4 | Communication Services | 0.44% |
| 5 | Healthcare | 0.42% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
26
UnitedHealth
UNH
$364B
| $61.8K | 0.02% |
+198
| New | +$75.7K |
|
27
Palantir
PLTR
$411B
| $60.1K | 0.02% |
+441
| New | +$51.7K |
|
28
Cisco
CSCO
$488B
| $59.7K | 0.02% |
+860
| New | +$52.9K |
|
29
GE Aerospace
GE
$379B
| $59.5K | 0.02% |
+231
| New | +$50.7K |
|
30
Coca-Cola
KO
$373B
| $59.1K | 0.02% |
+836
| New | +$59.6K |
|
31
IBM
IBM
$222B
| $58.7K | 0.02% |
+199
| New | +$51.3K |
|
32
Wells Fargo
WFC
$269B
| $57K | 0.02% |
+711
| New | +$51.3K |
|
33
Salesforce
CRM
$158B
| $56.2K | 0.02% |
+206
| New | +$55.1K |
|
34
Chevron
CVX
$386B
| $51.7K | 0.02% |
+361
| New | +$50.9K |
|
35
Abbott
ABT
$192B
| $50.9K | 0.02% |
+374
| New | +$49.3K |
|
36
Advanced Micro Devices
AMD
$788B
| $49.7K | 0.02% |
+350
| New | +$38.1K |
|
37
Walt Disney
DIS
$178B
| $48.4K | 0.02% |
+390
| New | +$40.5K |
|
38
Linde
LIN
$221B
| $47.9K | 0.02% |
+102
| New | +$46.6K |
|
39
Goldman Sachs
GS
$302B
| $47.4K | 0.02% |
+67
| New | +$38.8K |
|
40
Intuit
INTU
$91.6B
| $47.3K | 0.02% |
+60
| New | +$40.6K |
|
41
ServiceNow
NOW
$129B
| $45.2K | 0.02% |
+220
| New | +$41.5K |
|
42
AT&T
T
$166B
| $45.1K | 0.02% |
+1,557
| New | +$42.9K |
|
43
McDonald's
MCD
$195B
| $45K | 0.02% |
+154
| New | +$47.5K |
|
44
Merck
MRK
$328B
| $43.2K | 0.02% |
+546
| New | +$43.4K |
|
45
Uber
UBER
$154B
| $42.1K | 0.02% |
+451
| New | +$37.1K |
|
46
RTX Corp
RTX
$300B
| $41.9K | 0.02% |
+287
| New | +$38.2K |
|
47
Intuitive Surgical
ISRG
$142B
| $41.8K | 0.02% |
+77
| New | +$40.3K |
|
48
Texas Instruments
TXN
$253B
| $40.7K | 0.02% |
+196
| New | +$34.8K |
|
49
Booking.com
BKNG
$159B
| $40.5K | 0.02% |
+175
| New | +$35.8K |
|
50
Accenture
ACN
$110B
| $40.4K | 0.02% |
+135
| New | +$41.1K |
|
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Howard Hughes Medical Institute's Q2 2025 Portfolio in Review
As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.
Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.
By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.
On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.
- Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
- Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
- Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
- Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
- Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
- Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.
Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.