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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
Cap. Flow
+$25.5M
Cap. Flow %
10.17%
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1

Top Buys

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$15.6M
2
MSFT icon
Microsoft
MSFT
+$700K
3
NVDA icon
NVIDIA
NVDA
+$665K
4
AAPL icon
Apple
AAPL
+$653K
5
AMZN icon
Amazon
AMZN
+$403K

Top Sells

Rank Stock Value
1
BIOA
BioAge Labs
BIOA
+$428K

Sector Composition

Rank Sector Weight
1 Technology 1.55%
2 Financials 0.62%
3 Consumer Discretionary 0.47%
4 Communication Services 0.44%
5 Healthcare 0.42%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
TSN icon
401
Tyson Foods
TSN
$19.6B
$3.41K ﹤0.01%
+61
New +$3.51K
CF icon
402
CF Industries
CF
$18.2B
$3.4K ﹤0.01%
+37
New +$3.15K
ZBRA icon
403
Zebra Technologies
ZBRA
$17.9B
$3.39K ﹤0.01%
+11
New +$2.99K
ROL icon
404
Rollins
ROL
$17.6B
$3.38K ﹤0.01%
+60
New +$3.37K
EVRG icon
405
Evergy
EVRG
$19.2B
$3.38K ﹤0.01%
+49
New +$3.29K
APTV icon
406
Aptiv
APTV
$10.1B
$3.34K ﹤0.01%
+49
New +$3.03K
BAX icon
407
Baxter International
BAX
$13.9B
$3.33K ﹤0.01%
+110
New +$3.33K
LNT icon
408
Alliant Energy
LNT
$18.2B
$3.33K ﹤0.01%
+55
New +$3.37K
DECK icon
409
Deckers Outdoor
DECK
$12.4B
$3.3K ﹤0.01%
+32
New +$3.54K
WST icon
410
West Pharmaceutical
WST
$24.8B
$3.28K ﹤0.01%
+15
New +$3.21K
MOH icon
411
Molina Healthcare
MOH
$10.8B
$3.28K ﹤0.01%
+11
New +$3.45K
LYB icon
412
LyondellBasell Industries
LYB
$20.3B
$3.24K ﹤0.01%
+56
New +$3.26K
LVS icon
413
Las Vegas Sands
LVS
$29.6B
$3.22K ﹤0.01%
+74
New +$2.88K
DPZ icon
414
Domino's
DPZ
$11.7B
$3.15K ﹤0.01%
+7
New +$3.29K
TER icon
415
Teradyne
TER
$63B
$3.15K ﹤0.01%
+35
New +$2.8K
TXT icon
416
Textron
TXT
$15.3B
$3.13K ﹤0.01%
+39
New +$2.82K
HOLX
417
DELISTED
Hologic
HOLX
$3.13K ﹤0.01%
+48
New +$2.88K
CLX icon
418
Clorox
CLX
$12.8B
$3.12K ﹤0.01%
+26
New +$3.47K
KIM icon
419
Kimco Realty
KIM
$16.2B
$3.07K ﹤0.01%
+146
New +$3.03K
COO icon
420
Cooper Companies
COO
$15B
$3.06K ﹤0.01%
+43
New +$3.29K
EG icon
421
Everest Group
EG
$13.9B
$3.06K ﹤0.01%
+9
New +$3.1K
OMC icon
422
Omnicom Group
OMC
$23.5B
$3.02K ﹤0.01%
+42
New +$3.1K
AVY icon
423
Avery Dennison
AVY
$13.7B
$2.98K ﹤0.01%
+17
New +$2.98K
MAS icon
424
Masco
MAS
$14.7B
$2.9K ﹤0.01%
+45
New +$2.83K
ALGN icon
425
Align Technology
ALGN
$12.4B
$2.84K ﹤0.01%
+15
New +$2.65K
15 16
17
18 19

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ACM
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MCM
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MIA
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SP
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SWC
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VIS
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Howard Hughes Medical Institute's Q2 2025 Portfolio in Review

As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.

Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.

By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.

On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.

  • Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
  • Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
  • Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
  • Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
  • Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
  • Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.

Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.