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HHMI
Howard Hughes Medical Institute Portfolio holdings
AUM
$416M
1-Year Est. Return
13.82%
This Fund
S&P 500
This Quarter
Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
(+24%)
Cap. Flow
+$25.5M
Cap. Flow
% of AUM
10.17%
Top 10 Holdings %
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$15.6M |
| 2 |
Microsoft
MSFT
|
+$700K |
| 3 |
NVIDIA
NVDA
|
+$665K |
| 4 |
Apple
AAPL
|
+$653K |
| 5 |
Amazon
AMZN
|
+$403K |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
BIOA
BioAge Labs
BIOA
|
+$428K |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 1.55% |
| 2 | Financials | 0.62% |
| 3 | Consumer Discretionary | 0.47% |
| 4 | Communication Services | 0.44% |
| 5 | Healthcare | 0.42% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
301
United Airlines
UAL
$40.6B
| $5.65K | ﹤0.01% |
+71
| New | +$5.23K |
|
302
Synchrony
SYF
$25.8B
| $5.61K | ﹤0.01% |
+84
| New | +$4.7K |
|
303
Ameren
AEE
$30.1B
| $5.57K | ﹤0.01% |
+58
| New | +$5.63K |
|
304
Lennar Class A
LEN
$20.5B
| $5.53K | ﹤0.01% |
+50
| New | +$5.42K |
|
305
Warner Bros
WBD
$69.3B
| $5.51K | ﹤0.01% |
+481
| New | +$4.49K |
|
306
Diamondback Energy
FANG
$56.2B
| $5.5K | ﹤0.01% |
+40
| New | +$5.54K |
|
307
Darden Restaurants
DRI
$25.9B
| $5.45K | ﹤0.01% |
+25
| New | +$5.19K |
|
308
Archer Daniels Midland
ADM
$38.4B
| $5.44K | ﹤0.01% |
+103
| New | +$5.01K |
|
309
GoDaddy
GDDY
$11.6B
| $5.4K | ﹤0.01% |
+30
| New | +$5.38K |
|
310
SBA Communications
SBAC
$19.4B
| $5.4K | ﹤0.01% |
+23
| New | +$5.26K |
|
|
PPL
311
PPL Corp
PPL
$26.7B
| $5.39K | ﹤0.01% |
+159
| New | +$5.53K |
|
312
Dollar General
DG
$26.4B
| $5.38K | ﹤0.01% |
+47
| New | +$4.67K |
|
313
Constellation Brands
STZ
$22.9B
| $5.37K | ﹤0.01% |
+33
| New | +$5.92K |
|
314
Veralto
VLTO
$23.6B
| $5.35K | ﹤0.01% |
+53
| New | +$5.11K |
|
315
Tyler Technologies
TYL
$13B
| $5.34K | ﹤0.01% |
+9
| New | +$5.1K |
|
316
Northern Trust
NTRS
$35B
| $5.33K | ﹤0.01% |
+42
| New | +$4.29K |
|
317
Dover
DOV
$28B
| $5.31K | ﹤0.01% |
+29
| New | +$5.05K |
|
318
Super Micro Computer
SMCI
$24.3B
| $5.29K | ﹤0.01% |
+108
| New | +$4.16K |
|
319
International Paper
IP
$21.8B
| $5.29K | ﹤0.01% |
+113
| New | +$5.34K |
|
320
Huntington Bancshares
HBAN
$36.1B
| $5.26K | ﹤0.01% |
+314
| New | +$4.74K |
|
|
EXE
321
Expand Energy Corp
EXE
$22.3B
| $5.26K | ﹤0.01% |
+45
| New | +$5.02K |
|
322
Atmos Energy
ATO
$28.7B
| $5.24K | ﹤0.01% |
+34
| New | +$5.28K |
|
323
CenterPoint Energy
CNP
$26.7B
| $5.14K | ﹤0.01% |
+140
| New | +$5.19K |
|
324
Hershey
HSY
$37B
| $5.14K | ﹤0.01% |
+31
| New | +$5.11K |
|
325
Cboe Global Markets
CBOE
$30.4B
| $5.13K | ﹤0.01% |
+22
| New | +$4.9K |
|
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Howard Hughes Medical Institute's Q2 2025 Portfolio in Review
As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.
Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.
By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.
On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.
- Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
- Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
- Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
- Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
- Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
- Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.
Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.