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HHMI
Howard Hughes Medical Institute Portfolio holdings
AUM
$416M
1-Year Est. Return
13.82%
This Fund
S&P 500
This Quarter
Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
(+24%)
Cap. Flow
+$25.5M
Cap. Flow
% of AUM
10.17%
Top 10 Holdings %
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$15.6M |
| 2 |
Microsoft
MSFT
|
+$700K |
| 3 |
NVIDIA
NVDA
|
+$665K |
| 4 |
Apple
AAPL
|
+$653K |
| 5 |
Amazon
AMZN
|
+$403K |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
BIOA
BioAge Labs
BIOA
|
+$428K |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 1.55% |
| 2 | Financials | 0.62% |
| 3 | Consumer Discretionary | 0.47% |
| 4 | Communication Services | 0.44% |
| 5 | Healthcare | 0.42% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
276
Nucor
NUE
$61.9B
| $6.48K | ﹤0.01% |
+50
| New | +$5.84K |
|
277
Gartner
IT
$11.3B
| $6.47K | ﹤0.01% |
+16
| New | +$6.7K |
|
278
Iron Mountain
IRM
$37B
| $6.46K | ﹤0.01% |
+63
| New | +$5.94K |
|
279
Willis Towers Watson
WTW
$31.6B
| $6.44K | ﹤0.01% |
+21
| New | +$6.51K |
|
280
Humana
HUM
$46.7B
| $6.36K | ﹤0.01% |
+26
| New | +$6.48K |
|
281
Carnival Corporation Ltd
CCL
$37.9B
| $6.36K | ﹤0.01% |
+226
| New | +$4.84K |
|
|
ANSS
282
DELISTED
Ansys
ANSS
| $6.32K | ﹤0.01% |
+18
| New | +$5.89K |
|
283
DuPont de Nemours
DD
$19.5B
| $6.17K | ﹤0.01% |
+72
| New | +$5.99K |
|
284
General Mills
GIS
$20.4B
| $6.17K | ﹤0.01% |
+119
| New | +$6.57K |
|
285
Occidental Petroleum
OXY
$58.5B
| $6.13K | ﹤0.01% |
+146
| New | +$6.1K |
|
286
AvalonBay Communities
AVB
$25.7B
| $6.11K | ﹤0.01% |
+30
| New | +$6.13K |
|
287
Broadridge
BR
$19.3B
| $6.08K | ﹤0.01% |
+25
| New | +$5.94K |
|
288
Tractor Supply
TSCO
$19B
| $6.07K | ﹤0.01% |
+115
| New | +$5.88K |
|
289
Keysight
KEYS
$60.6B
| $6.06K | ﹤0.01% |
+37
| New | +$5.64K |
|
290
Raymond James Financial
RJF
$34.9B
| $5.98K | ﹤0.01% |
+39
| New | +$5.58K |
|
291
Ventas
VTR
$45.7B
| $5.94K | ﹤0.01% |
+94
| New | +$6.14K |
|
|
FITB
292
Fifth Third Bancorp
FITB
$52.6B
| $5.92K | ﹤0.01% |
+144
| New | +$5.4K |
|
293
American Water Works
AWK
$26.8B
| $5.84K | ﹤0.01% |
+42
| New | +$6.02K |
|
294
DTE Energy
DTE
$28.9B
| $5.83K | ﹤0.01% |
+44
| New | +$5.92K |
|
295
Centene
CNC
$33.1B
| $5.81K | ﹤0.01% |
+107
| New | +$6.28K |
|
296
Hewlett Packard
HPE
$77.8B
| $5.79K | ﹤0.01% |
+283
| New | +$4.74K |
|
297
lululemon athletica
LULU
$13.7B
| $5.7K | ﹤0.01% |
+24
| New | +$6.61K |
|
298
PPG Industries
PPG
$25.5B
| $5.69K | ﹤0.01% |
+50
| New | +$5.41K |
|
299
IQVIA
IQV
$39.8B
| $5.67K | ﹤0.01% |
+36
| New | +$5.42K |
|
300
Brown & Brown
BRO
$23.8B
| $5.65K | ﹤0.01% |
+51
| New | +$5.73K |
|
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Howard Hughes Medical Institute's Q2 2025 Portfolio in Review
As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.
Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.
By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.
On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.
- Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
- Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
- Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
- Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
- Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
- Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.
Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.