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HHMI
Howard Hughes Medical Institute Portfolio holdings
AUM
$416M
1-Year Est. Return
13.82%
This Fund
S&P 500
This Quarter
Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
(+24%)
Cap. Flow
+$25.5M
Cap. Flow
% of AUM
10.17%
Top 10 Holdings %
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$15.6M |
| 2 |
Microsoft
MSFT
|
+$700K |
| 3 |
NVIDIA
NVDA
|
+$665K |
| 4 |
Apple
AAPL
|
+$653K |
| 5 |
Amazon
AMZN
|
+$403K |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
BIOA
BioAge Labs
BIOA
|
+$428K |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 1.55% |
| 2 | Financials | 0.62% |
| 3 | Consumer Discretionary | 0.47% |
| 4 | Communication Services | 0.44% |
| 5 | Healthcare | 0.42% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
226
Ametek
AME
$59.3B
| $8.87K | ﹤0.01% |
+49
| New | +$8.43K |
|
227
CBRE Group
CBRE
$42.7B
| $8.83K | ﹤0.01% |
+63
| New | +$7.97K |
|
228
Take-Two Interactive
TTWO
$45.4B
| $8.74K | ﹤0.01% |
+36
| New | +$8.11K |
|
229
Cardinal Health
CAH
$54.5B
| $8.74K | ﹤0.01% |
+52
| New | +$7.72K |
|
230
Corning
GLW
$144B
| $8.73K | ﹤0.01% |
+166
| New | +$7.77K |
|
231
Kenvue
KVUE
$36.5B
| $8.66K | ﹤0.01% |
+414
| New | +$9.42K |
|
232
Xcel Energy
XEL
$49.1B
| $8.44K | ﹤0.01% |
+124
| New | +$8.6K |
|
233
Otis Worldwide
OTIS
$28.2B
| $8.42K | ﹤0.01% |
+85
| New | +$8.21K |
|
234
Cognizant
CTSH
$26.2B
| $8.27K | ﹤0.01% |
+106
| New | +$8.12K |
|
235
Dell
DELL
$313B
| $8.21K | ﹤0.01% |
+67
| New | +$6.85K |
|
236
Targa Resources
TRGP
$57.6B
| $8.18K | ﹤0.01% |
+47
| New | +$7.89K |
|
237
Charter Communications
CHTR
$17.9B
| $8.18K | ﹤0.01% |
+20
| New | +$7.66K |
|
|
HES
238
DELISTED
Hess
HES
| $8.17K | ﹤0.01% |
+59
| New | +$7.97K |
|
239
Baker Hughes
BKR
$63.8B
| $8.17K | ﹤0.01% |
+213
| New | +$8.04K |
|
240
Prudential Financial
PRU
$42.3B
| $8.16K | ﹤0.01% |
+76
| New | +$7.87K |
|
241
Microchip Technology
MCHP
$43.1B
| $8.16K | ﹤0.01% |
+116
| New | +$6.38K |
|
|
EA
242
DELISTED
Electronic Arts
EA
| $8.14K | ﹤0.01% |
+51
| New | +$7.54K |
|
243
ResMed
RMD
$32.8B
| $8K | ﹤0.01% |
+31
| New | +$7.39K |
|
244
Rockwell Automation
ROK
$50.1B
| $7.97K | ﹤0.01% |
+24
| New | +$6.84K |
|
245
Nasdaq
NDAQ
$53.5B
| $7.96K | ﹤0.01% |
+89
| New | +$7.11K |
|
246
Sysco
SYY
$40.5B
| $7.95K | ﹤0.01% |
+105
| New | +$7.62K |
|
247
Hartford Financial Services
HIG
$37.7B
| $7.87K | ﹤0.01% |
+62
| New | +$7.71K |
|
248
D.R. Horton
DHI
$40.8B
| $7.86K | ﹤0.01% |
+61
| New | +$7.51K |
|
249
eBay
EBAY
$45.5B
| $7.67K | ﹤0.01% |
+103
| New | +$7.3K |
|
250
Entergy
ETR
$50.3B
| $7.65K | ﹤0.01% |
+92
| New | +$7.6K |
|
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Howard Hughes Medical Institute's Q2 2025 Portfolio in Review
As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.
Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.
By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.
On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.
- Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
- Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
- Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
- Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
- Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
- Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.
Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.