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FCMV

Foresite Capital Management V Portfolio holdings

AUM $271M
1-Year Est. Return 309.87%
This Fund
S&P 500
This Quarter Est. Return
+64.27%
1 Year Est. Return
+309.87%
3 Year Est. Return
+356.88%
5 Year Est. Return
+250.56%
10 Year Est. Return
AUM
$164M
AUM Growth
+$55.7M
Cap. Flow
+$14M
Cap. Flow %
8.55%
Top 10 Hldgs %
100%
Holding
7
New
1
Increased
Reduced
Closed

Top Buys

Rank Stock Value
1
NTRA icon
Natera
NTRA
+$14M

Top Sells

No sells this quarter

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
ALMS
1
Alumis Inc
ALMS
$3.65B
$56.4M 34.31%
5,779,348
CGON icon
2
CG Oncology
CGON
$6.34B
$41.7M 25.36%
1,004,050
IRON icon
3
Disc Medicine
IRON
$2.91B
$23.7M 14.45%
299,069
NTRA icon
4
Natera
NTRA
$38.9B
$15.4M 9.39%
+67,356
New +$14M
LYEL icon
5
Lyell Immunopharma
LYEL
$326M
$14.7M 8.93%
477,078
HIMS icon
6
Hims & Hers Health
HIMS
$7.6B
$8.87M 5.39%
273,151
MAZE
7
Maze Therapeutics
MAZE
$1.56B
$3.58M 2.17%
86,291

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Foresite Capital Management V's Q4 2025 Portfolio in Review

As of Q4 2025, Foresite Capital Management V held 7 positions worth $164M, up 51% from $109M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Foresite Capital Management V deployed $14M of net new capital in Q4 2025, opening 1 new position. Its largest new stake was Natera: 67,356 shares worth $15.4M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

  • Foresite Capital Management V's largest Q4 2025 buy was Natera: 67,356 shares worth $15.4M.
  • Foresite Capital Management V's ten largest holdings make up 100% of its $164M portfolio in Q4 2025.
  • Foresite Capital Management V opened 1 new position and closed 0 in Q4 2025.
  • Foresite Capital Management V's portfolio value rose 51% quarter-over-quarter to $164M.

Based on Foresite Capital Management V's 13F filing for Q4 2025, filed 17 Feb 2026.