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FCMI

Foresite Capital Management II Portfolio holdings

AUM $29.2M
1-Year Est. Return 44.84%
This Fund
S&P 500
This Quarter Est. Return
+27.84%
1 Year Est. Return
+44.84%
3 Year Est. Return
-66.21%
5 Year Est. Return
-36.36%
10 Year Est. Return
AUM
$286M
AUM Growth
+$39.5M
Cap. Flow
-$15.3M
Cap. Flow %
-5.33%
Top 10 Hldgs %
99.99%
Holding
15
New
3
Increased
2
Reduced
3
Closed
4

Top Buys

Rank Stock Value
1
INSM icon
Insmed
INSM
+$6.46M
2
DNLI icon
Denali Therapeutics
DNLI
+$4.49M
3
QURE icon
uniQure
QURE
+$1.66M
4
EPZM
Epizyme, Inc
EPZM
+$218K

Sector Composition

Rank Sector Weight
1 Healthcare 22.75%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
AIMT
1
DELISTED
Aimmune Therapeutics
AIMT
$117M 40.96%
3,100,146
-720,316
-19% -$23.2M
AERI
2
DELISTED
Aerie Pharmaceuticals
AERI
$99.9M 34.92%
1,672,714
EPZM
3
DELISTED
Epizyme, Inc
EPZM
$19.6M 6.83%
1,558,108
+15,000
+1% +$218K
INSM icon
4
Insmed
INSM
$23B
$16.2M 5.65%
518,645
+218,645
+73% +$6.46M
ALDR
5
DELISTED
Alder Biopharmaceuticals
ALDR
$12M 4.18%
1,043,832
XLRN
6
DELISTED
Acceleron Pharma
XLRN
$10.4M 3.63%
244,756
DNLI icon
7
Denali Therapeutics
DNLI
$3.76B
$3.91M 1.37%
+250,000
New +$4.49M
JUNO
8
DELISTED
Juno Therapeutics, Inc.
JUNO
$3.88M 1.36%
85,000
-5,000
-6% -$249K
QURE icon
9
uniQure
QURE
$2.68B
$2.14M 0.75%
+109,350
New +$1.66M
LOXO
10
DELISTED
Loxo Oncology, Inc
LOXO
$1M 0.35%
11,900
-2,400
-17% -$200K
ALDR
11
CALL
DELISTED
Alder Biopharmaceuticals
ALDR
$40K 0.01%
+24,000
New +$268K
LRMR icon
12
Larimar Therapeutics
LRMR
$396M
-2,565
Closed -$108K
JNCE
13
DELISTED
Jounce Therapeutics, Inc. Common Stock
JNCE
-119,912
Closed -$1.87M
DERM
14
DELISTED
Dermira, Inc.
DERM
-58,624
Closed -$1.58M
OREX
15
DELISTED
Orexigen Therapeutics, Inc.
OREX
-523,132
Closed -$1.11M

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Foresite Capital Management II's Q4 2017 Portfolio in Review

As of Q4 2017, Foresite Capital Management II held 15 positions worth $286M, up 16% from $247M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Foresite Capital Management II withdrew a net $15.3M in Q4 2017, closing 4 positions and reducing 3 holdings. Its most notable exit was Jounce Therapeutics, Inc. Common Stock, an estimated $1.87M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 23% of assets, down from 26% a quarter earlier.

Against the trend, Foresite Capital Management II opened a new position in Denali Therapeutics worth $3.91M.

  • Foresite Capital Management II's largest Q4 2017 buy was Denali Therapeutics: 250,000 shares worth $3.91M.
  • Foresite Capital Management II added most to Insmed in Q4 2017, an estimated $6.46M increase.
  • Foresite Capital Management II's biggest Q4 2017 reduction was Aimmune Therapeutics, cutting an estimated $23.2M.
  • Foresite Capital Management II fully exited Jounce Therapeutics, Inc. Common Stock in Q4 2017, selling an estimated $1.87M.
  • Foresite Capital Management II's ten largest holdings make up 100% of its $286M portfolio in Q4 2017.
  • Foresite Capital Management II opened 3 new positions and closed 4 in Q4 2017.
  • Foresite Capital Management II's portfolio value rose 16% quarter-over-quarter to $286M.

Based on Foresite Capital Management II's 13F filing for Q4 2017, filed 13 Feb 2018.