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David Shaw’s Twist Bioscience TWST Stock Holding History

David Shaw’s Portfolio TWST Stock Details TWST Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2022
Q4 		– Sell
-20,000
Closed -$705K – 5136
2022
Q3 		$705K Hold
20,000
– – ﹤0.01% 3831
2022
Q2 		$699K Buy
+20,000
New +$708K ﹤0.01% 3858

Other funds holding TWST

BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Artisan Partners
Artisan Partners Milwaukee, Wisconsin $63.1B AUM 35.51% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
AIM
ARK Investment Management St. Petersburg, Florida $15.4B AUM 50.29% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
EIG
EdgePoint Investment Group Toronto, Ontario, Canada $13.2B AUM 32.43% 1-Year Est. Return
William Blair Investment Management
William Blair Investment Management Chicago, Illinois $33.3B AUM 44.76% 1-Year Est. Return

David Shaw's TWST Position: Q2 2026 in Review

David Shaw increased its Twist Bioscience (TWST) stake by 2,442% in Q2 2026, buying an estimated $74.1M and bringing the position to 1,185,605 shares worth $122M. The position accounts for 0.06% of the portfolio, ranked #376.

David Shaw first reported a position in TWST in Q4 2018 and has held it in 23 quarters since. 334 funds tracked by Wall St. Rank hold TWST as of Q2 2026.

  • David Shaw held 1,185,605 shares of Twist Bioscience worth $122M as of Q2 2026.
  • David Shaw bought 1,138,961 Twist Bioscience shares in Q2 2026, an estimated $74.1M.
  • Twist Bioscience made up 0.06% of David Shaw's portfolio in Q2 2026, its #376 holding.
  • David Shaw first reported a position in Twist Bioscience in Q4 2018 and has held it in 23 quarters since.
  • 334 funds tracked by Wall St. Rank held Twist Bioscience as of Q2 2026.

Based on D.E. Shaw & Co's 13F filing for Q2 2026, filed 14 Aug 2026.