D.E. Shaw & Co Portfolio holdings
D. E. Shaw & Co., L.P., founded in 1988 by David E. Shaw, a former Columbia University computer science professor, is a New York City-based global investment management firm renowned for pioneering quantitative investing, managing over $70 billion in assets as of late 2024. Starting with $28 million from Paloma Partners and private investors, the firm employs sophisticated mathematical models and proprietary algorithms—initially developed by a team of scientists and programmers—to exploit market anomalies across public and private markets, including equities, fixed income, and alternatives. Headquartered above a Greenwich Village bookstore in its early days, it now boasts over 2,500 employees across offices in North America, Europe, and Asia, led by a seven-member Executive Committee since Shaw stepped back in 2001 to focus on D. E. Shaw Research. Despite setbacks like the 1998 Russia debt crisis and the 2008 financial downturn, the firm has maintained a reputation for analytical rigor, risk management, and innovation, balancing its computational roots with discretionary strategies.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Microsoft
MSFT
|
+$1.9B |
| 2 |
Broadcom
AVGO
|
+$1.07B |
| 3 |
NVIDIA
NVDA
|
+$908M |
| 4 |
Meta Platforms (Facebook)
META
|
+$861M |
| 5 |
Intuitive Surgical
ISRG
|
+$666M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$1.68B |
| 2 |
Apple
AAPL
|
+$1.31B |
| 3 |
State Street Financial Select Sector SPDR ETF
XLF
|
+$789M |
| 4 |
GE Aerospace
GE
|
+$653M |
| 5 |
Applovin
APP
|
+$634M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 19.25% |
| 2 | Consumer Discretionary | 7.51% |
| 3 | Financials | 7.11% |
| 4 | Healthcare | 6.95% |
| 5 | Industrials | 6.31% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
|
AGEN
3801
Agenus
AGEN
$267M
| $440K | ﹤0.01% |
+114,329
| New | +$572K |
|
3802
ProShares Ultra VIX Short-Term Futures ETF
UVXY
$233M
| $439K | ﹤0.01% |
8,409
-729
| -8% | -$50.7K |
|
3803
PUT
ATI
ATI
$25.5B
| $439K | ﹤0.01% |
+5,400
| New | +$438K |
|
|
VZLA
3804
Vizsla Silver
VZLA
$1.12B
| $438K | ﹤0.01% |
101,400
-180,042
| -64% | -$624K |
|
3805
IES Holdings
IESC
$10.9B
| $437K | ﹤0.01% |
1,100
| – | – |
|
3806
Revolution Medicines Inc Warrant
RVMDW
$97.8M
| $436K | ﹤0.01% |
1,454,895
| – | – |
|
3807
Global X DAX Germany ETF
DAX
$225M
| $435K | ﹤0.01% |
9,712
+1,023
| +12% | +$45.7K |
|
3808
iShares MSCI Australia ETF
EWA
$1.39B
| $434K | ﹤0.01% |
16,084
-45,871
| -74% | -$1.22M |
|
3809
PUT
Range Resources
RRC
$8.86B
| $433K | ﹤0.01% |
+11,500
| New | +$411K |
|
3810
CALL
American International
AIG
$42.6B
| $432K | ﹤0.01% |
+5,500
| New | +$440K |
|
3811
Plains GP Holdings
PAGP
$5.17B
| $430K | ﹤0.01% |
23,600
| – | – |
|
|
SA
3812
CALL
Seabridge Gold
SA
$2.72B
| $430K | ﹤0.01% |
17,800
+5,600
| +46% | +$96.9K |
|
3813
iShares US Healthcare Providers ETF
IHF
$1.24B
| $429K | ﹤0.01% |
+8,695
| New | +$397K |
|
3814
PUT
AutoZone
AZO
$50.7B
| $429K | ﹤0.01% |
+100
| New | +$401K |
|
3815
PUT
Procept Biorobotics
PRCT
$1.02B
| $428K | ﹤0.01% |
+12,000
| New | +$548K |
|
|
JHG
3816
DELISTED
Janus Henderson
JHG
| $428K | ﹤0.01% |
9,622
-249,570
| -96% | -$10.8M |
|
3817
Great Southern Bancorp
GSBC
$880M
| $427K | ﹤0.01% |
6,966
+567
| +9% | +$34.6K |
|
3818
CALL
DaVita
DVA
$15.4B
| $425K | ﹤0.01% |
3,200
| – | – |
|
3819
Rackspace Technology
RXT
$960M
| $425K | ﹤0.01% |
301,351
-351,694
| -54% | -$471K |
|
|
AOMR
3820
Angel Oak Mortgage REIT
AOMR
$223M
| $425K | ﹤0.01% |
45,313
+10,721
| +31% | +$103K |
|
3821
Codexis
CDXS
$137M
| $424K | ﹤0.01% |
+173,805
| New | +$474K |
|
3822
Lakeland Industries
LAKE
$108M
| $422K | ﹤0.01% |
+28,516
| New | +$415K |
|
3823
MGP Ingredients
MGPI
$402M
| $422K | ﹤0.01% |
17,432
-6,948
| -28% | -$201K |
|
3824
Global X Data Center & Digital Infrastructure ETF
DTCR
$2.1B
| $421K | ﹤0.01% |
+20,555
| New | +$394K |
|
3825
Cytek Biosciences
CTKB
$584M
| $420K | ﹤0.01% |
+121,022
| New | +$454K |
|
Similar funds
D.E. Shaw & Co's Q3 2025 Portfolio in Review
As of Q3 2025, D.E. Shaw & Co held 5,023 positions worth $177B, up 26% from $141B the previous quarter. Its ten largest holdings account for 13% of the portfolio.
D.E. Shaw & Co deployed $15.2B of net new capital in Q3 2025, opening 714 new positions and adding to 1,743 existing holdings. Its largest new stake was iShares iBoxx $ Investment Grade Corporate Bond ETF: 3,319,000 shares worth $370M.
By sector, the portfolio is most concentrated in Technology at 19% of assets, up from 16% a quarter earlier, followed by Consumer Discretionary and Financials.
On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $1.68B trimmed.
- D.E. Shaw & Co's largest Q3 2025 buy was iShares iBoxx $ Investment Grade Corporate Bond ETF: 3,319,000 shares worth $370M.
- D.E. Shaw & Co added most to Microsoft in Q3 2025, an estimated $1.9B increase.
- D.E. Shaw & Co's biggest Q3 2025 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $1.68B.
- D.E. Shaw & Co fully exited Hess in Q3 2025, selling an estimated $527M.
- D.E. Shaw & Co's ten largest holdings make up 13% of its $177B portfolio in Q3 2025.
- D.E. Shaw & Co opened 714 new positions and closed 514 in Q3 2025.
- D.E. Shaw & Co's portfolio value rose 26% quarter-over-quarter to $177B.
Based on D.E. Shaw & Co's 13F filing for Q3 2025, filed 14 Nov 2025.