D.E. Shaw & Co
THRD

D.E. Shaw & Co’s Third Harmonic Bio THRD Stock Holding History

D.E. Shaw & Co’s Portfolio THRD Stock Details THRD Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-1,250,680
Closed -$6.79M – 4929
2025
Q2 		$6.79M Buy
1,250,680
+677,346
+118% +$3.38M ﹤0.01% 1795
2025
Q1 		$1.99M Buy
573,334
+562,334
+5,112% +$2.73M ﹤0.01% 2599
2024
Q4 		$113K Sell
11,000
-2,967
-21% -$37K ﹤0.01% 4158
2024
Q3 		$189K Buy
+13,967
New +$173K ﹤0.01% 4173
2024
Q2 		– Sell
-28,974
Closed -$274K – 4838
2024
Q1 		$274K Buy
28,974
+2,213
+8% +$21.5K ﹤0.01% 3778
2023
Q4 		$294K Buy
+26,761
New +$212K ﹤0.01% 3751

Other funds holding THRD

Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $481B AUM 30.42% 1-Year Est. Return
CF
Cantor Fitzgerald New York $6.78B AUM 29.01% 1-Year Est. Return
RhumbLine Advisers
RhumbLine Advisers Boston, Massachusetts $117B AUM 29.66% 1-Year Est. Return
MIM
MetLife Investment Management Whippany, New Jersey $19.6B AUM 32.64% 1-Year Est. Return
JC
JBF Capital Aspen, Colorado $676M AUM 24.74% 1-Year Est. Return
Russell Investments Group
Russell Investments Group London, United Kingdom $93.1B AUM 28.26% 1-Year Est. Return
AB
Amalgamated Bank New York $13.1B AUM 29.66% 1-Year Est. Return
GI
GAMMA Investing Foster City, California $2.69B AUM 42.78% 1-Year Est. Return
Optiver Holding
Optiver Holding Amsterdam, Netherlands $289B AUM 33.63% 1-Year Est. Return
N
Nuveen Charlotte, North Carolina $369B AUM 31.66% 1-Year Est. Return

D.E. Shaw & Co's THRD Position: Q3 2025 in Review

D.E. Shaw & Co sold out of Third Harmonic Bio (THRD) in Q3 2025, closing a stake of 1,250,680 shares — an estimated $6.79M sold.

D.E. Shaw & Co first reported a position in THRD in Q4 2023 and held it in 6 quarters. The position peaked at $6.79M in Q2 2025. 18 funds tracked by Wall St. Rank hold THRD as of Q3 2025.

  • D.E. Shaw & Co reported no remaining Third Harmonic Bio position as of Q3 2025 after selling out during the quarter.
  • D.E. Shaw & Co sold 1,250,680 Third Harmonic Bio shares in Q3 2025, an estimated $6.79M.
  • D.E. Shaw & Co first reported a position in Third Harmonic Bio in Q4 2023 and held it in 6 quarters.
  • D.E. Shaw & Co's Third Harmonic Bio position peaked at $6.79M in Q2 2025.
  • 18 funds tracked by Wall St. Rank held Third Harmonic Bio as of Q3 2025.

Based on D.E. Shaw & Co's 13F filing for Q3 2025, filed 14 Nov 2025.