D.E. Shaw & Co
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D.E. Shaw & Co’s Prothena Corp PRTA Stock Holding History

D.E. Shaw & Co’s Portfolio PRTA Stock Details PRTA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2024
Q3 		– Sell
-11,100
Closed -$229K – 4800
2024
Q2 		$229K Buy
+11,100
New +$240K ﹤0.01% 4024
2022
Q3 		– Sell
-13,400
Closed -$364K – 5457
2022
Q2 		$364K Hold
13,400
– – ﹤0.01% 4275
2022
Q1 		$490K Hold
13,400
– – ﹤0.01% 4381
2021
Q4 		$662K Sell
13,400
-18,600
-58% -$1.03M ﹤0.01% 4232
2021
Q3 		$2.28M Buy
+32,000
New +$1.99M ﹤0.01% 2915
2019
Q1 		– Sell
-46,000
Closed -$474K – 3859
2018
Q4 		$474K Buy
+46,000
New +$547K ﹤0.01% 3119
2016
Q1 		– Sell
-20,000
Closed -$1.36M – 3705
2015
Q4 		$1.36M Buy
+20,000
New +$1.21M ﹤0.01% 2438

Other funds holding PRTA

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
RCMNY
Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
ACM
ADAR1 Capital Management Austin, Texas $1.7B AUM 340.85% 1-Year Est. Return
Acadian Asset Management
Acadian Asset Management Boston, Massachusetts $70.5B AUM 36% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
PAI
Palo Alto Investors Palo Alto, California $654M AUM 77.8% 1-Year Est. Return
Two Sigma Investments
Two Sigma Investments New York $124B AUM 33.93% 1-Year Est. Return

D.E. Shaw & Co's PRTA Position: Q1 2026 in Review

D.E. Shaw & Co increased its Prothena Corp (PRTA) stake by 4.9% in Q1 2026, buying an estimated $751K and bringing the position to 1,763,347 shares worth $17.1M. The position accounts for 0.01% of the portfolio, ranked #1252.

D.E. Shaw & Co first reported a position in PRTA in Q2 2014 and has held it in 34 quarters since. 185 funds tracked by Wall St. Rank hold PRTA as of Q1 2026.

  • D.E. Shaw & Co held 1,763,347 shares of Prothena Corp worth $17.1M as of Q1 2026.
  • D.E. Shaw & Co bought 81,978 Prothena Corp shares in Q1 2026, an estimated $751K.
  • Prothena Corp made up 0.01% of D.E. Shaw & Co's portfolio in Q1 2026, its #1252 holding.
  • D.E. Shaw & Co first reported a position in Prothena Corp in Q2 2014 and has held it in 34 quarters since.
  • 185 funds tracked by Wall St. Rank held Prothena Corp as of Q1 2026.

Based on D.E. Shaw & Co's 13F filing for Q1 2026, filed 15 May 2026.