D.E. Shaw & Co’s Prothena Corp PRTA Stock Holding History

D.E. Shaw & Co’s Portfolio PRTA Stock Details PRTA Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2024 Q3	–	Sell	-11,100	Closed	-$229K	–	4800
2024 Q2	$229K	Buy	+11,100	New	+$240K	﹤0.01%	4024
2022 Q3	–	Sell	-13,400	Closed	-$364K	–	5457
2022 Q2	$364K	Hold	13,400	–	–	﹤0.01%	4275
2022 Q1	$490K	Hold	13,400	–	–	﹤0.01%	4381
2021 Q4	$662K	Sell	13,400 -18,600	-58%	-$1.03M	﹤0.01%	4232
2021 Q3	$2.28M	Buy	+32,000	New	+$1.99M	﹤0.01%	2915
2019 Q1	–	Sell	-46,000	Closed	-$474K	–	3859
2018 Q4	$474K	Buy	+46,000	New	+$547K	﹤0.01%	3119
2016 Q1	–	Sell	-20,000	Closed	-$1.36M	–	3705
2015 Q4	$1.36M	Buy	+20,000	New	+$1.21M	﹤0.01%	2438

Other funds holding PRTA

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

RCMNY

Rubric Capital Management (New York) New York $10.9B AUM 70.31% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Acadian Asset Management Boston, Massachusetts $84.2B AUM 55.88% 1-Year Est. Return

Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM

ACM

ADAR1 Capital Management Austin, Texas $2.19B AUM 374.99% 1-Year Est. Return

Two Sigma Investments New York $138B AUM 41.87% 1-Year Est. Return

PAI

Palo Alto Investors Palo Alto, California $724M AUM 96.91% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

D.E. Shaw & Co's PRTA Position: Q2 2026 in Review

D.E. Shaw & Co reduced its Prothena Corp (PRTA) stake by 8.6% in Q2 2026, selling an estimated $1.5M and leaving 1,611,457 shares worth $15.8M. The position accounts for 0.01% of the portfolio, ranked #1465.

D.E. Shaw & Co first reported a position in PRTA in Q2 2014 and has held it in 35 quarters since. The position peaked at $17.1M in Q1 2026. 188 funds tracked by Wall St. Rank hold PRTA as of Q2 2026.

D.E. Shaw & Co held 1,611,457 shares of Prothena Corp worth $15.8M as of Q2 2026.
D.E. Shaw & Co sold 151,890 Prothena Corp shares in Q2 2026, an estimated $1.5M.
Prothena Corp made up 0.01% of D.E. Shaw & Co's portfolio in Q2 2026, its #1465 holding.
D.E. Shaw & Co first reported a position in Prothena Corp in Q2 2014 and has held it in 35 quarters since.
D.E. Shaw & Co's Prothena Corp position peaked at $17.1M in Q1 2026.
188 funds tracked by Wall St. Rank held Prothena Corp as of Q2 2026.

Based on D.E. Shaw & Co's 13F filing for Q2 2026, filed 14 Aug 2026.