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Column Group Portfolio holdings

AUM $101M
1-Year Est. Return 290.34%
This Fund
S&P 500
This Quarter Est. Return
+24.4%
1 Year Est. Return
+290.34%
3 Year Est. Return
+185.99%
5 Year Est. Return
+29.33%
10 Year Est. Return
AUM
$82.8M
AUM Growth
+$1.83M
Cap. Flow
+$5.38M
Cap. Flow %
6.5%
Top 10 Hldgs %
100%
Holding
5
New
Increased
1
Reduced
1
Closed

Top Buys

Rank Stock Value
1
SRZN icon
Surrozen
SRZN
+$5.69M

Top Sells

Rank Stock Value
1
RAPT
RAPT Therapeutics
RAPT
+$304K

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
SRZN icon
1
Surrozen
SRZN
$229M
$41.8M 50.54%
1,851,350
+351,577
+23% +$5.69M
ORIC icon
2
Oric Pharmaceuticals
ORIC
$1.25B
$29M 34.98%
3,540,777
TNYA icon
3
Tenaya Therapeutics
TNYA
$168M
$6.69M 8.08%
9,400,290
RAPT
4
DELISTED
RAPT Therapeutics
RAPT
$5.29M 6.39%
156,270
-9,805
-6% -$304K
RVMD icon
5
Revolution Medicines
RVMD
$40.2B
$3.66K ﹤0.01%
46

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Column Group's Q4 2025 Portfolio in Review

As of Q4 2025, Column Group held 5 positions worth $82.8M, up 2.3% from $81M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Column Group deployed $5.38M of net new capital in Q4 2025, adding to 1 existing holding.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

On the sell side, the largest reduction was RAPT Therapeutics, an estimated $304K trimmed.

  • Column Group added most to Surrozen in Q4 2025, an estimated $5.69M increase.
  • Column Group's biggest Q4 2025 reduction was RAPT Therapeutics, cutting an estimated $304K.
  • Column Group's ten largest holdings make up 100% of its $82.8M portfolio in Q4 2025.
  • Column Group opened 0 new positions and closed 0 in Q4 2025.
  • Column Group's portfolio value rose 2.3% quarter-over-quarter to $82.8M.

Based on Column Group's 13F filing for Q4 2025, filed 13 Feb 2026.