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Checkpoint Capital Portfolio holdings

AUM $279M
1-Year Est. Return 45.74%
This Fund
S&P 500
This Quarter Est. Return
-11.8%
1 Year Est. Return
+45.74%
3 Year Est. Return
–
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$279M
AUM Growth
-$41.4M
Cap. Flow
-$3.54M
Cap. Flow %
-1.27%
Top 10 Hldgs %
100%
Holding
10
New
3
Increased
3
Reduced
2
Closed
2

Top Buys

Rank Stock Value
1
RYTM icon
Rhythm Pharmaceuticals
RYTM
+$22.9M
2
ARGX icon
argenx
ARGX
+$8.61M
3
SEPN
Septerna Inc
SEPN
+$2.64M
4
CRNX icon
Crinetics Pharmaceuticals
CRNX
+$1.8M
5
CYTK icon
Cytokinetics
CYTK
+$837K

Top Sells

Rank Stock Value
1
CORT icon
Corcept Therapeutics
CORT
+$14M
2
IRON icon
Disc Medicine
IRON
+$11.5M
3
RVMD icon
Revolution Medicines
RVMD
+$10.9M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ARGX icon
1
argenx
ARGX
$54.1B
$112M 40.1%
153,000
+11,000
+8% +$8.61M
RYTM icon
2
Rhythm Pharmaceuticals
RYTM
$7.96B
$107M 38.3%
1,227,200
+235,000
+24% +$22.9M
RVMD icon
3
Revolution Medicines
RVMD
$44B
$25.5M 9.16%
262,539
-107,461
-29% -$10.9M
IRON icon
4
Disc Medicine
IRON
$2.97B
$18.3M 6.58%
286,661
-166,331
-37% -$11.5M
CYTK icon
5
Cytokinetics
CYTK
$10.4B
$11.9M 4.26%
180,000
+13,177
+8% +$837K
SEPN
6
Septerna Inc
SEPN
$1.75B
$2.41M 0.87%
+100,300
New +$2.64M
CRNX icon
7
Crinetics Pharmaceuticals
CRNX
$8.92B
$1.46M 0.52%
+40,230
New +$1.8M
TRVI icon
8
Trevi Therapeutics
TRVI
$2.64B
$597K 0.21%
+50,000
New +$560K
CORT icon
9
CALL
Corcept Therapeutics
CORT
$12B
– –
-128,300
Closed -$4.46M
CORT icon
10
Corcept Therapeutics
CORT
$12B
– –
-401,395
Closed -$14M

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Checkpoint Capital's Q1 2026 Portfolio in Review

As of Q1 2026, Checkpoint Capital held 10 positions worth $279M, down 13% from $320M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Checkpoint Capital's Q1 2026 filing shows 3 new, 3 increased, 2 reduced and 2 closed positions. Its largest new stake was Septerna Inc: 100,300 shares worth $2.41M. The largest sale was Corcept Therapeutics, an estimated $14M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 99% a quarter earlier.

  • Checkpoint Capital's largest Q1 2026 buy was Septerna Inc: 100,300 shares worth $2.41M.
  • Checkpoint Capital added most to Rhythm Pharmaceuticals in Q1 2026, an estimated $22.9M increase.
  • Checkpoint Capital's biggest Q1 2026 reduction was Disc Medicine, cutting an estimated $11.5M.
  • Checkpoint Capital fully exited Corcept Therapeutics in Q1 2026, selling an estimated $14M.
  • Checkpoint Capital's ten largest holdings make up 100% of its $279M portfolio in Q1 2026.
  • Checkpoint Capital opened 3 new positions and closed 2 in Q1 2026.
  • Checkpoint Capital's portfolio value fell 13% quarter-over-quarter to $279M.

Based on Checkpoint Capital's 13F filing for Q1 2026, filed 15 May 2026.