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Checkpoint Capital Portfolio holdings

AUM $390M
1-Year Est. Return 96.52%
This Fund
S&P 500
This Quarter Est. Return
+39.94%
1 Year Est. Return
+96.52%
3 Year Est. Return
–
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$390M
AUM Growth
+$111M
Cap. Flow
+$14.4M
Cap. Flow %
3.7%
Top 10 Hldgs %
100%
Holding
8
New
–
Increased
3
Reduced
3
Closed
2

Top Buys

Rank Stock Value
1
RVMD icon
Revolution Medicines
RVMD
+$21.6M
2
CYTK icon
Cytokinetics
CYTK
+$21.2M
3
TRVI icon
Trevi Therapeutics
TRVI
+$364K

Top Sells

Rank Stock Value
1
ARGX icon
argenx
ARGX
+$17.9M
2
RYTM icon
Rhythm Pharmaceuticals
RYTM
+$3.73M
3
IRON icon
Disc Medicine
IRON
+$3.2M
4
SEPN
Septerna Inc
SEPN
+$2.41M
5
CRNX
Crinetics Pharmaceuticals
CRNX
+$1.46M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
RYTM icon
1
Rhythm Pharmaceuticals
RYTM
$6.79B
$132M 33.79%
1,186,000
-41,200
-3% -$3.73M
ARGX icon
2
argenx
ARGX
$60B
$122M 31.25%
131,283
-21,717
-14% -$17.9M
RVMD icon
3
Revolution Medicines
RVMD
$43.9B
$76.9M 19.72%
410,353
+147,814
+56% +$21.6M
CYTK icon
4
Cytokinetics
CYTK
$8.99B
$40.5M 10.38%
475,000
+295,000
+164% +$21.2M
IRON icon
5
Disc Medicine
IRON
$2.5B
$17.6M 4.51%
240,125
-46,536
-16% -$3.2M
TRVI icon
6
Trevi Therapeutics
TRVI
$2.05B
$1.4M 0.36%
75,000
+25,000
+50% +$364K
CRNX
7
DELISTED
Crinetics Pharmaceuticals
CRNX
– –
-40,230
Closed -$1.46M
SEPN
8
Septerna Inc
SEPN
$1.76B
– –
-100,300
Closed -$2.41M

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Checkpoint Capital's Q2 2026 Portfolio in Review

As of Q2 2026, Checkpoint Capital held 8 positions worth $390M, up 40% from $279M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Checkpoint Capital deployed $14.4M of net new capital in Q2 2026, adding to 3 existing holdings.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

On the sell side, the largest reduction was argenx, an estimated $17.9M trimmed.

  • Checkpoint Capital added most to Revolution Medicines in Q2 2026, an estimated $21.6M increase.
  • Checkpoint Capital's biggest Q2 2026 reduction was argenx, cutting an estimated $17.9M.
  • Checkpoint Capital fully exited Septerna Inc in Q2 2026, selling an estimated $2.41M.
  • Checkpoint Capital's ten largest holdings make up 100% of its $390M portfolio in Q2 2026.
  • Checkpoint Capital opened 0 new positions and closed 2 in Q2 2026.
  • Checkpoint Capital's portfolio value rose 40% quarter-over-quarter to $390M.

Based on Checkpoint Capital's 13F filing for Q2 2026, filed 14 Aug 2026.