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BWLSA

Blue Water Life Science Advisors Portfolio holdings

AUM $125M
1-Year Est. Return 91.82%
This Fund
S&P 500
This Quarter Est. Return
+32.15%
1 Year Est. Return
+91.82%
3 Year Est. Return
+242.79%
5 Year Est. Return
+115.88%
10 Year Est. Return
–
AUM
$159M
AUM Growth
+$49.7M
Cap. Flow
+$17.9M
Cap. Flow %
11.24%
Top 10 Hldgs %
100%
Holding
9
New
2
Increased
2
Reduced
2
Closed
–

Top Buys

Rank Stock Value
1
TWST icon
Twist Bioscience
TWST
+$11.9M
2
GRAL
GRAIL Inc
GRAL
+$8.55M
3
QTRX icon
Quanterix
QTRX
+$7.05M
4
TEM
Tempus AI
TEM
+$1.1M

Top Sells

Rank Stock Value
1
ADPT icon
Adaptive Biotechnologies
ADPT
+$6.2M
2
GH icon
Guardant Health
GH
+$4.53M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
GH icon
1
Guardant Health
GH
$19B
$36.3M 22.76%
355,047
-50,600
-12% -$4.53M
NTRA icon
2
Natera
NTRA
$36.1B
$32.4M 20.34%
141,494
– –
ADPT icon
3
Adaptive Biotechnologies
ADPT
$3.6B
$28.7M 17.99%
1,765,145
-380,000
-18% -$6.2M
PSNL icon
4
Personalis
PSNL
$1.27B
$13.3M 8.37%
1,676,300
– –
QTRX icon
5
Quanterix
QTRX
$164M
$13.3M 8.35%
2,092,147
+1,134,400
+118% +$7.05M
TWST icon
6
Twist Bioscience
TWST
$5.51B
$12.1M 7.63%
+383,000
New +$11.9M
CDNA icon
7
CareDx
CDNA
$1.85B
$9.61M 6.03%
510,000
– –
GRAL
8
GRAIL Inc
GRAL
$2.76B
$8.47M 5.32%
+99,000
New +$8.55M
TEM
9
Tempus AI
TEM
$7.72B
$5.1M 3.2%
86,412
+14,000
+19% +$1.1M

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Blue Water Life Science Advisors's Q4 2025 Portfolio in Review

As of Q4 2025, Blue Water Life Science Advisors held 9 positions worth $159M, up 45% from $110M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Blue Water Life Science Advisors deployed $17.9M of net new capital in Q4 2025, opening 2 new positions and adding to 2 existing holdings. Its largest new stake was Twist Bioscience: 383,000 shares worth $12.1M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

On the sell side, the largest reduction was Adaptive Biotechnologies, an estimated $6.2M trimmed.

  • Blue Water Life Science Advisors's largest Q4 2025 buy was Twist Bioscience: 383,000 shares worth $12.1M.
  • Blue Water Life Science Advisors added most to Quanterix in Q4 2025, an estimated $7.05M increase.
  • Blue Water Life Science Advisors's biggest Q4 2025 reduction was Adaptive Biotechnologies, cutting an estimated $6.2M.
  • Blue Water Life Science Advisors's ten largest holdings make up 100% of its $159M portfolio in Q4 2025.
  • Blue Water Life Science Advisors opened 2 new positions and closed 0 in Q4 2025.
  • Blue Water Life Science Advisors's portfolio value rose 45% quarter-over-quarter to $159M.

Based on Blue Water Life Science Advisors's 13F filing for Q4 2025, filed 17 Feb 2026.