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APM

Avidity Partners Management Portfolio holdings

AUM $624M Turnover 44.83%
1-Year Est. Return 250.2%
This Fund
S&P 500
This Quarter Est. Return
+25.49%
1 Year Est. Return
+250.2%
3 Year Est. Return
+491.63%
5 Year Est. Return
+985.37%
10 Year Est. Return
–
AUM
$4.62B
AUM Growth
-$303M
Cap. Flow
-$726M
Cap. Flow %
-15.73%
Top 10 Hldgs %
43.33%
Holding
116
New
19
Increased
32
Reduced
19
Closed
31
Avg Time Held Equity + Options
0.8 years
Top 10 Avg Time Held Equity + Options
0.2 years
Top 20 Avg Time Held Equity + Options
0.4 years
Avg Time Held Equity only
0.8 years
Top 10 Avg Time Held Equity only
0.2 years
Top 20 Avg Time Held Equity only
0.4 years

Sector Composition

Rank Sector Weight
1 Healthcare 92.28%
2 Miscellaneous 7.3%
3 Financials 0.42%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow Held Since
ALT icon
26
Altimmune
ALT
$428M
$65.6M 1.42%
3,990,000
+1,306,000
+49% +$14.7M
2021 Q3
5 quarters
RVMD icon
27
Revolution Medicines
RVMD
$38.1B
$59M 1.28%
2,475,000
+153,800
+7% +$3.27M
2022 Q2
2 quarters
KRTX icon
28
DELISTED
Karuna Therapeutics, Inc. Common Stock
KRTX
$58.8M 1.27%
299,000
-132,800
-31% -$28.5M
2022 Q2
2 quarters
ARWR icon
29
Arrowhead Research
ARWR
$7.9B
$55.8M 1.21%
1,375,000
+119,626
+10% +$3.96M
2021 Q2
6 quarters
AXSM icon
30
Axsome Therapeutics
AXSM
$8.23B
$51.7M 1.12%
670,000
-868,600
-56% -$51.9M
2022 Q3
1 quarter
VRTX icon
31
Vertex Pharmaceuticals
VRTX
$127B
$49.7M 1.08%
172,000
-340,800
-66% -$104M
2020 Q4
8 quarters
LEGN icon
32
Legend Biotech
LEGN
$3.59B
$48.4M 1.05%
+970,000
New +$47M
2022 Q4
0 quarters
KZR icon
33
DELISTED
Kezar Life Sciences
KZR
$47.7M 1.03%
678,240
+136,800
+25% +$10.1M
2021 Q3
5 quarters
PLRX icon
34
Pliant Therapeutics
PLRX
$55.7M
$43.3M 0.94%
2,240,400
+259,300
+13% +$5.42M
2022 Q3
1 quarter
VTYX icon
35
DELISTED
Ventyx Biosciences
VTYX
$42.1M 0.91%
+1,285,000
New +$38.1M
2022 Q4
0 quarters
ICLR icon
36
Icon
ICLR
$13.1B
$41.8M 0.9%
+215,000
New +$42.6M
2022 Q4
0 quarters
DGX icon
37
Quest Diagnostics
DGX
$25.9B
$40.4M 0.87%
+258,000
New +$37.1M
2022 Q4
0 quarters
BIO icon
38
Bio-Rad Laboratories Class A
BIO
$9.46B
$38.8M 0.84%
92,200
-52,600
-36% -$21.2M
2022 Q3
1 quarter
BLU
39
DELISTED
BELLUS Health Inc.
BLU
$37.8M 0.82%
4,599,998
+253,298
+6% +$2.36M
2020 Q4
8 quarters
THC icon
40
Tenet Healthcare
THC
$21.5B
$35M 0.76%
+717,300
New +$33.2M
2022 Q4
0 quarters
KPTI icon
41
Karyopharm Therapeutics
KPTI
$8.85M
$32.8M 0.71%
+642,261
New +$44.5M
2022 Q4
0 quarters
BNTX icon
42
BioNTech
BNTX
$22B
$32.4M 0.7%
+215,400
New +$33.1M
2022 Q4
0 quarters
VERV icon
43
DELISTED
Verve Therapeutics
VERV
$30.3M 0.66%
1,565,000
+522,294
+50% +$13.8M
2022 Q3
1 quarter
RCKT icon
44
Rocket Pharmaceuticals
RCKT
$239M
$29.9M 0.65%
+1,527,087
New +$28.1M
2022 Q4
0 quarters
ITCI icon
45
DELISTED
Intra-Cellular Therapies Inc.
ITCI
$26.7M 0.58%
504,000
-898,500
-64% -$45M
2022 Q2
2 quarters
ARQT icon
46
Arcutis Biotherapeutics
ARQT
$3.62B
$26M 0.56%
1,755,000
+960,500
+121% +$16.8M
2022 Q3
1 quarter
RXDX
47
DELISTED
Prometheus Biosciences, Inc. Common Stock
RXDX
$22.4M 0.49%
+204,000
New +$13.2M
2022 Q4
0 quarters
NTLA icon
48
Intellia Therapeutics
NTLA
$1.6B
$22.3M 0.48%
638,200
-360,900
-36% -$17.2M
2022 Q1
3 quarters
VIR icon
49
Vir Biotechnology
VIR
$1.69B
$21.5M 0.47%
+850,000
New +$20.8M
2022 Q4
0 quarters
PHAT icon
50
Phathom Pharmaceuticals
PHAT
$560M
$21.3M 0.46%
1,900,000
-6,800
-0.4% -$70.1K
2021 Q4
4 quarters

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Avidity Partners Management's Q4 2022 Portfolio in Review

As of Q4 2022, Avidity Partners Management held 116 positions worth $4.62B, down 6.2% from $4.92B the previous quarter. Its ten largest holdings account for 43% of the portfolio.

Avidity Partners Management withdrew a net $726M in Q4 2022, closing 31 positions and reducing 19 holdings. Its most notable exit was Biogen, an estimated $160M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 92% of assets, up from 91% a quarter earlier, followed by Miscellaneous and Financials.

Against the trend, Avidity Partners Management opened a new position in Universal Health Services worth $116M.

  • Avidity Partners Management's largest Q4 2022 buy was Universal Health Services: 825,600 shares worth $116M.
  • Avidity Partners Management added most to Surgery Partners in Q4 2022, an estimated $75.3M increase.
  • Avidity Partners Management's biggest Q4 2022 reduction was Eli Lilly, cutting an estimated $280M.
  • Avidity Partners Management fully exited Biogen in Q4 2022, selling an estimated $160M.
  • Avidity Partners Management's ten largest holdings make up 43% of its $4.62B portfolio in Q4 2022.
  • Avidity Partners Management opened 19 new positions and closed 31 in Q4 2022.
  • Avidity Partners Management's portfolio value fell 6.2% quarter-over-quarter to $4.62B.

Based on Avidity Partners Management's 13F filing for Q4 2022, filed 14 Feb 2023.