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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+12.83%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$63.1B
AUM Growth
+$3.79B
Cap. Flow
-$1.12B
Cap. Flow %
-1.77%
Top 10 Hldgs %
32.11%
Holding
999
New
156
Increased
303
Reduced
370
Closed
127

Top Buys

Rank Stock Value
1
CVX icon
Chevron
CVX
+$509M
2
RPRX icon
Royalty Pharma
RPRX
+$216M
3
JNJ icon
Johnson & Johnson
JNJ
+$159M
4
PG icon
Procter & Gamble
PG
+$134M
5
LBRDK icon
Liberty Broadband Class C
LBRDK
+$133M

Top Sells

Rank Stock Value
1
HES
Hess
HES
+$1.35B
2
INSM icon
Insmed
INSM
+$197M
3
HUBB icon
Hubbell
HUBB
+$191M
4
ARGX icon
argenx
ARGX
+$164M
5
SLNO
Soleno Therapeutics
SLNO
+$161M

Sector Composition

Rank Sector Weight
1 Technology 30.31%
2 Healthcare 13.97%
3 Financials 11.89%
4 Consumer Discretionary 9.55%
5 Communication Services 9.08%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
AIT icon
826
Applied Industrial Technologies
AIT
$13.3B
$1.37M ﹤0.01%
+5,256
New +$1.38M
ALGS icon
827
Aligos Therapeutics
ALGS
$34.1M
$1.37M ﹤0.01%
140,000
– –
APLT
828
DELISTED
Applied Therapeutics
APLT
$1.34M ﹤0.01%
2,211,629
+1,000,000
+83% +$471K
IMUX icon
829
Immunic
IMUX
$198M
$1.23M ﹤0.01%
139,860
– –
PCH
830
DELISTED
PotlatchDeltic
PCH
$1.22M ﹤0.01%
30,000
-385,000
-93% -$16M
ATI icon
831
ATI
ATI
$30.5B
$1.22M ﹤0.01%
+15,000
New +$1.22M
SRZN icon
832
Surrozen
SRZN
$251M
$1.14M ﹤0.01%
88,653
– –
SITE icon
833
SiteOne Landscape Supply
SITE
$4.3B
$1.13M ﹤0.01%
+8,773
New +$1.19M
CHE icon
834
Chemed
CHE
$7.18B
$1.12M ﹤0.01%
2,500
-2,000
-44% -$906K
PKG icon
835
Packaging Corp of America
PKG
$22.5B
$959K ﹤0.01%
4,400
-137,400
-97% -$28.3M
RAL
836
Ralliant Corp
RAL
$7.3B
$837K ﹤0.01%
19,151
-183,356
-91% -$8.15M
PUMP icon
837
ProPetro Holding
PUMP
$1.34B
$786K ﹤0.01%
150,000
-75,000
-33% -$398K
PDYN icon
838
Palladyne AI
PDYN
$278M
$716K ﹤0.01%
83,333
– –
RGEN icon
839
Repligen
RGEN
$9B
$668K ﹤0.01%
+5,000
New +$607K
TENX icon
840
Tenax Therapeutics
TENX
$498M
$634K ﹤0.01%
83,333
– –
TRAW icon
841
Traws Pharma
TRAW
$8.21M
$611K ﹤0.01%
330,000
– –
LZM.WS icon
842
Lifezone Metals Ltd Warrants
LZM.WS
$27.4M
$588K ﹤0.01%
933,579
-298,218
-24% -$129K
IMA
843
ImageneBio Inc
IMA
$64M
$543K ﹤0.01%
66,666
-1
-0% -$13
EPSN icon
844
Epsilon Energy
EPSN
$170M
$513K ﹤0.01%
101,835
-720,210
-88% -$4.37M
IFRX icon
845
InflaRx
IFRX
$253M
$444K ﹤0.01%
331,113
– –
OMC icon
846
Omnicom Group
OMC
$22.6B
$434K ﹤0.01%
+5,327
New +$402K
BGLWW
847
Blue Gold Ltd Warrant
BGLWW
$518K
$400K ﹤0.01%
875,000
-25,000
-3% -$11.5K
VERU icon
848
Veru
VERU
$37.1M
$380K ﹤0.01%
100,000
– –
LBRT icon
849
Liberty Energy
LBRT
$3.27B
$370K ﹤0.01%
30,000
-10,000
-25% -$116K
NUAI
850
New Era Energy & Digital Inc
NUAI
$523M
$368K ﹤0.01%
200,000
-500,000
-71% -$277K
32 33
34
35 36

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Adage Capital Partners's Q3 2025 Portfolio in Review

As of Q3 2025, Adage Capital Partners held 999 positions worth $63.1B, up 6.4% from $59.3B the previous quarter. Its ten largest holdings account for 32% of the portfolio.

Adage Capital Partners's Q3 2025 filing shows 156 new, 303 increased, 370 reduced and 127 closed positions. Its largest new stake was Chevron: 3,284,841 shares worth $510M. The largest sale was Hess, an estimated $1.35B.

By sector, the portfolio is most concentrated in Technology at 30% of assets, up from 29% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q3 2025 buy was Chevron: 3,284,841 shares worth $510M.
  • Adage Capital Partners added most to Royalty Pharma in Q3 2025, an estimated $216M increase.
  • Adage Capital Partners's biggest Q3 2025 reduction was Insmed, cutting an estimated $197M.
  • Adage Capital Partners fully exited Hess in Q3 2025, selling an estimated $1.35B.
  • Adage Capital Partners's ten largest holdings make up 32% of its $63.1B portfolio in Q3 2025.
  • Adage Capital Partners opened 156 new positions and closed 127 in Q3 2025.
  • Adage Capital Partners's portfolio value rose 6.4% quarter-over-quarter to $63.1B.

Based on Adage Capital Partners's 13F filing for Q3 2025, filed 14 Nov 2025.