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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+1.53%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+829.83%
AUM
$64.8B
AUM Growth
-$1.23B
Cap. Flow
+$395M
Cap. Flow %
0.61%
Top 10 Hldgs %
28.4%
Holding
1,116
New
212
Increased
277
Reduced
389
Closed
160

Top Buys

Rank Stock Value
1
RVMD icon
Revolution Medicines
RVMD
+$330M
2
CTRA
Coterra Energy
CTRA
+$214M
3
BSX icon
Boston Scientific
BSX
+$204M
4
RBA icon
RB Global
RBA
+$183M
5
CVX icon
Chevron
CVX
+$131M

Top Sells

Rank Stock Value
1
RNAM
Avidity Biosciences
RNAM
+$190M
2
RPRX icon
Royalty Pharma
RPRX
+$187M
3
DOV icon
Dover
DOV
+$178M
4
BA icon
Boeing
BA
+$168M
5
DVN icon
Devon Energy
DVN
+$155M

Sector Composition

Rank Sector Weight
1 Technology 27.24%
2 Healthcare 15.45%
3 Financials 12.46%
4 Industrials 9.23%
5 Communication Services 8.79%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ANTX icon
801
AN2 Therapeutics
ANTX
$177M
$3.42M 0.01%
+1,000,000
New +$2.06M
URI icon
802
United Rentals
URI
$71.1B
$3.37M 0.01%
4,621
-45,550
-91% -$38.3M
HELP
803
Cybin Inc
HELP
$472M
$3.36M 0.01%
700,000
– –
EVTL icon
804
Vertical Aerospace
EVTL
$176M
$3.31M 0.01%
1,500,000
+489,899
+49% +$2.23M
ATRA icon
805
Atara Biotherapeutics
ATRA
$71.2M
$3.31M 0.01%
+700,000
New +$4.27M
NJR icon
806
New Jersey Resources
NJR
$6.06B
$3.3M 0.01%
+60,000
New +$3.1M
PGEN icon
807
Precigen
PGEN
$1.93B
$3.27M 0.01%
846,000
– –
TRIP icon
808
TripAdvisor
TRIP
$1.59B
$3.2M ﹤0.01%
+300,000
New +$3.49M
HSIC icon
809
Henry Schein
HSIC
$9.74B
$3.12M ﹤0.01%
+42,300
New +$3.27M
PVLA
810
Palvella Therapeutics
PVLA
$1.98B
$3.12M ﹤0.01%
+25,000
New +$2.61M
NWS icon
811
News Corp Class B
NWS
$16.4B
$3.11M ﹤0.01%
109,034
-2,400
-2% -$67.7K
FULC icon
812
Fulcrum Therapeutics
FULC
$248M
$3.07M ﹤0.01%
400,000
-1,300,000
-76% -$12.1M
HLX icon
813
Helix Energy Solutions
HLX
$1.46B
$2.97M ﹤0.01%
300,000
-1,000,000
-77% -$8.51M
CNC icon
814
Centene
CNC
$31.3B
$2.95M ﹤0.01%
+90,039
New +$3.69M
CLDT
815
Chatham Lodging
CLDT
$630M
$2.78M ﹤0.01%
352,973
-471,749
-57% -$3.51M
TROW icon
816
T. Rowe Price
TROW
$25B
$2.63M ﹤0.01%
29,201
-86,829
-75% -$8.41M
CNTX icon
817
Context Therapeutics
CNTX
$56.4M
$2.62M ﹤0.01%
+1,000,000
New +$2.34M
FR icon
818
First Industrial Realty Trust
FR
$8.88B
$2.6M ﹤0.01%
45,000
-178,703
-80% -$10.6M
KRRO icon
819
Korro Bio
KRRO
$153M
$2.59M ﹤0.01%
+228,400
New +$2.51M
SRZN icon
820
Surrozen
SRZN
$229M
$2.58M ﹤0.01%
88,653
– –
CEPV
821
Cantor Equity Partners V
CEPV
$332M
$2.52M ﹤0.01%
250,000
– –
PSKY
822
Paramount Skydance Corp
PSKY
$9.19B
$2.5M ﹤0.01%
277,271
-3,300
-1% -$36.1K
NBP
823
NovaBridge Biosciences American Depositary Shares
NBP
$205M
$2.46M ﹤0.01%
1,000,000
– –
SIRI icon
824
SiriusXM
SIRI
$10B
$2.46M ﹤0.01%
106,402
-100,000
-48% -$2.15M
RNA
825
Atrium Therapeutics
RNA
$197M
$2.45M ﹤0.01%
+183,580
New +$2.58M
31 32
33
34 35

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Adage Capital Partners's Q1 2026 Portfolio in Review

As of Q1 2026, Adage Capital Partners held 1,116 positions worth $64.8B, down 1.9% from $66.1B the previous quarter. Its ten largest holdings account for 28% of the portfolio.

Adage Capital Partners's Q1 2026 filing shows 212 new, 277 increased, 389 reduced and 160 closed positions. Its largest new stake was Takeda Pharmaceutical: 6,424,984 shares worth $119M. The largest sale was Avidity Biosciences, an estimated $190M.

By sector, the portfolio is most concentrated in Technology at 27% of assets, down from 29% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q1 2026 buy was Takeda Pharmaceutical: 6,424,984 shares worth $119M.
  • Adage Capital Partners added most to Revolution Medicines in Q1 2026, an estimated $330M increase.
  • Adage Capital Partners's biggest Q1 2026 reduction was Royalty Pharma, cutting an estimated $187M.
  • Adage Capital Partners fully exited Avidity Biosciences in Q1 2026, selling an estimated $190M.
  • Adage Capital Partners's ten largest holdings make up 28% of its $64.8B portfolio in Q1 2026.
  • Adage Capital Partners opened 212 new positions and closed 160 in Q1 2026.
  • Adage Capital Partners's portfolio value fell 1.9% quarter-over-quarter to $64.8B.

Based on Adage Capital Partners's 13F filing for Q1 2026, filed 15 May 2026.