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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+12.83%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$63.1B
AUM Growth
+$3.79B
Cap. Flow
-$1.12B
Cap. Flow %
-1.77%
Top 10 Hldgs %
32.11%
Holding
999
New
156
Increased
303
Reduced
370
Closed
127

Top Buys

Rank Stock Value
1
CVX icon
Chevron
CVX
+$509M
2
RPRX icon
Royalty Pharma
RPRX
+$216M
3
JNJ icon
Johnson & Johnson
JNJ
+$159M
4
PG icon
Procter & Gamble
PG
+$134M
5
LBRDK icon
Liberty Broadband Class C
LBRDK
+$133M

Top Sells

Rank Stock Value
1
HES
Hess
HES
+$1.35B
2
INSM icon
Insmed
INSM
+$197M
3
HUBB icon
Hubbell
HUBB
+$191M
4
ARGX icon
argenx
ARGX
+$164M
5
SLNO
Soleno Therapeutics
SLNO
+$161M

Sector Composition

Rank Sector Weight
1 Technology 30.31%
2 Healthcare 13.97%
3 Financials 11.89%
4 Consumer Discretionary 9.55%
5 Communication Services 9.08%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MNPR icon
226
Monopar Therapeutics
MNPR
$805M
$53.8M 0.09%
659,195
+60,000
+10% +$2.68M
PSX icon
227
Phillips 66
PSX
$82.4B
$53.4M 0.08%
392,901
-5,300
-1% -$679K
ACAD icon
228
Acadia Pharmaceuticals
ACAD
$4.9B
$53M 0.08%
2,484,156
+1,880,356
+311% +$44.5M
APO icon
229
Apollo Global Management
APO
$73.7B
$52.4M 0.08%
393,400
+25,900
+7% +$3.67M
RNAM
230
DELISTED
Avidity Biosciences
RNAM
$52.3M 0.08%
1,200,000
-327,000
-21% -$13.2M
NXPI icon
231
NXP Semiconductors
NXPI
$58.4B
$52.3M 0.08%
229,508
+8,100
+4% +$1.82M
PYPL icon
232
PayPal
PYPL
$51.1B
$52.2M 0.08%
778,675
+17,900
+2% +$1.26M
NDAQ icon
233
Nasdaq
NDAQ
$52.9B
$52.1M 0.08%
589,347
+10,707
+2% +$992K
LHX icon
234
L3Harris
LHX
$53.9B
$52M 0.08%
170,159
-603
-0.4% -$165K
AZN icon
235
AstraZeneca
AZN
$250B
$51.6M 0.08%
336,472
+173,776
+107% +$26.3M
FCX icon
236
Freeport-McMoran
FCX
$95.5B
$51.3M 0.08%
1,307,100
-273,300
-17% -$11.9M
AXON
237
Axon Enterprise
AXON
$42.1B
$51.2M 0.08%
71,400
-5,300
-7% -$4.02M
IR icon
238
Ingersoll Rand
IR
$34.2B
$51M 0.08%
617,472
+247,980
+67% +$20.3M
SNDX icon
239
Syndax Pharmaceuticals
SNDX
$1.76B
$51M 0.08%
3,311,963
+1,879,523
+131% +$24.6M
CI icon
240
Cigna
CI
$72.7B
$50M 0.08%
173,602
-57,961
-25% -$17.1M
NUVL
241
DELISTED
Nuvalent
NUVL
$49.7M 0.08%
574,500
-3,000
-0.5% -$237K
FOX icon
242
Fox Class B
FOX
$23.2B
$49.3M 0.08%
860,065
+389,200
+83% +$20.5M
BBIO icon
243
BridgeBio Pharma
BBIO
$16.2B
$49.1M 0.08%
944,846
+643,485
+214% +$31.4M
ROK icon
244
Rockwell Automation
ROK
$49.2B
$48.6M 0.08%
139,018
-63,975
-32% -$22.1M
UAL icon
245
United Airlines
UAL
$41.9B
$48.2M 0.08%
499,737
+200,628
+67% +$19.3M
RGA icon
246
Reinsurance Group of America
RGA
$15.5B
$48M 0.08%
250,000
-100,000
-29% -$19.1M
CMG icon
247
Chipotle Mexican Grill
CMG
$42.7B
$47.8M 0.08%
1,220,650
-1,644,384
-57% -$74M
PTGX icon
248
Protagonist Therapeutics
PTGX
$9.4B
$47.7M 0.08%
718,202
-374,060
-34% -$21.3M
HAS icon
249
Hasbro
HAS
$12.9B
$47.1M 0.07%
621,272
+167,600
+37% +$13M
URI icon
250
United Rentals
URI
$72.4B
$46.9M 0.07%
49,169
-25,305
-34% -$22.5M
8 9
10
11 12

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Adage Capital Partners's Q3 2025 Portfolio in Review

As of Q3 2025, Adage Capital Partners held 999 positions worth $63.1B, up 6.4% from $59.3B the previous quarter. Its ten largest holdings account for 32% of the portfolio.

Adage Capital Partners's Q3 2025 filing shows 156 new, 303 increased, 370 reduced and 127 closed positions. Its largest new stake was Chevron: 3,284,841 shares worth $510M. The largest sale was Hess, an estimated $1.35B.

By sector, the portfolio is most concentrated in Technology at 30% of assets, up from 29% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q3 2025 buy was Chevron: 3,284,841 shares worth $510M.
  • Adage Capital Partners added most to Royalty Pharma in Q3 2025, an estimated $216M increase.
  • Adage Capital Partners's biggest Q3 2025 reduction was Insmed, cutting an estimated $197M.
  • Adage Capital Partners fully exited Hess in Q3 2025, selling an estimated $1.35B.
  • Adage Capital Partners's ten largest holdings make up 32% of its $63.1B portfolio in Q3 2025.
  • Adage Capital Partners opened 156 new positions and closed 127 in Q3 2025.
  • Adage Capital Partners's portfolio value rose 6.4% quarter-over-quarter to $63.1B.

Based on Adage Capital Partners's 13F filing for Q3 2025, filed 14 Nov 2025.