ASND icon

Ascendis Pharma

199.59 USD
+2.35
1.19%
At close Updated Sep 17, 4:00 PM EDT
Pre-market
After hours
199.59
0.00
0%
1 day
1.19%
5 days
0.68%
1 month
2.84%
3 months
15.44%
6 months
18.21%
Year to date
44.63%
1 year
36.16%
5 years
36.98%
10 years
899.95%
 

About: Ascendis Pharma AS is a biopharmaceutical company that applies its TransCon technology platform to make a meaningful difference for patients. The firm's product pipeline includes Endocrinology and Oncology which includes TransCon PTH, TransCon CNP, and others. It operates in North America, Europe, and Rest of the world and derives the majority of its revenue from North America.

Employees: 1,017

0
Funds holding %
of 7,463 funds
0
Analysts bullish %
of 10 analysts

Fund manager confidence

Based on 2025 Q2 regulatory disclosures by fund managers ($100M+ AUM)

210% more call options, than puts

Call options by funds: $39.2M | Put options by funds: $12.6M

14% more funds holding in top 10

Funds holding in top 10: 14 [Q1] → 16 (+2) [Q2]

10% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 40

7% more capital invested

Capital invested by funds: $10.1B [Q1] → $10.9B (+$708M) [Q2]

1% more funds holding

Funds holding: 241 [Q1] → 244 (+3) [Q2]

2% less repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 85

4.51% less ownership

Funds ownership: 107.4% [Q1] → 102.88% (-4.51%) [Q2]

Research analyst outlook

10 Wall Street Analysts provided 1 year price targets over the past 3 months

Low target
$203
2% upside
Avg. target
$254
27% upside
High target
$307
54% upside

10 analyst ratings

10  positive
100%
neutral
0%
negative
0%
B of A Securities
Tazeen Ahmad
$230
Buy
Maintained
2 Sep 2025
JP Morgan
Jessica Fye
$260
Overweight
Maintained
19 Aug 2025
Citigroup
David Lebowitz
$290
Buy
Maintained
8 Aug 2025
RBC Capital
Luca Issi
$230
Outperform
Maintained
8 Aug 2025
Wedbush
Yun Zhong
$220
Outperform
Maintained
8 Aug 2025

Financial journalist opinion

Neutral
GlobeNewsWire
15 days ago
Ascendis to Share Latest Endocrinology Rare Disease Data in 3 Oral Presentations at ASBMR 2025
COPENHAGEN, Denmark, Sept. 02, 2025 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced three oral presentations of its latest achondroplasia and hypoparathyroidism data at ASBMR 2025, the annual meeting of the American Society for Bone & Mineral Research being held in Seattle from September 5-8, 2025.
Ascendis to Share Latest Endocrinology Rare Disease Data in 3 Oral Presentations at ASBMR 2025
Neutral
GlobeNewsWire
20 days ago
Ascendis Pharma to Participate in the 2025 Wells Fargo Healthcare Conference
COPENHAGEN, Denmark, Aug. 28, 2025 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced that company executives will participate in a fireside chat at the 2025 Wells Fargo Healthcare Conference on Wednesday, September 3, 2025, at 8:00 a.m. Eastern Time / 5:00 a.m. Pacific Time in Boston, Massachusetts.
Ascendis Pharma to Participate in the 2025 Wells Fargo Healthcare Conference
Neutral
Seeking Alpha
1 month ago
Ascendis Pharma A/S (ASND) Q2 2025 Earnings Call Transcript
Ascendis Pharma A/S (ASND) Q2 2025 Earnings Conference Call August 7, 2025 4:30 PM ET Company Participants Jan Moller Mikkelsen - President, CEO, Member of Executive Board & Executive Director Jay Donovan Wu - Executive VP & President of Ascendis US Scott T. Smith - CFO, Executive VP & Member of Executive Board Conference Call Participants Alexander Thompson - Stifel, Nicolaus & Company, Incorporated, Research Division David Neil Lebowitz - Citigroup Inc., Research Division Derek Christian Archila - Wells Fargo Securities, LLC, Research Division Dingding Shi - Jefferies LLC, Research Division Eliana Rachel Merle - UBS Investment Bank, Research Division Gavin Clark-Gartner - Evercore ISI Institutional Equities, Research Division Jessica Macomber Fye - JPMorgan Chase & Co, Research Division Joori Park - Leerink Partners LLC, Research Division Leland James Gershell - Oppenheimer & Co. Inc., Research Division Luca Issi - RBC Capital Markets, Research Division Maxwell Nathan Skor - Morgan Stanley, Research Division Paul Choi - Goldman Sachs Group, Inc., Research Division Tazeen Ahmad - BofA Securities, Research Division Yaron Benjamin Werber - TD Cowen, Research Division Yun Zhong - Wedbush Securities Inc., Research Division Operator Good day, and thank you for standing by.
Ascendis Pharma A/S (ASND) Q2 2025 Earnings Call Transcript
Neutral
GlobeNewsWire
1 month ago
Ascendis Pharma Reports Second Quarter 2025 Financial Results
– Q2 2025 revenue of €103.0 million for YORVIPATH ® and €50.7 million for SKYTROFA ® – TransCon ® CNP (navepegritide) NDA under Priority Review for the treatment of children with achondroplasia with PDUFA date of November 30, 2025 – SKYTROFA ® (lonapegsomatropin-tcgd) approved in the U.S. for treatment of adults with growth hormone deficiency; first of many planned label expansions  – Week 26 Interim Results for COACH trial highlight the unique portfolio of once-weekly TransCon CNP and once-weekly TransCon hGH, with complementary modes of action, to potentially further transform the treatment landscape for growth disorders and physical functioning –Conference call today at 4:30 pm ET COPENHAGEN, Aug. 07, 2025 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced financial results for the second quarter ended June 30, 2025, and provided a business update. “With the robust global uptake of YORVIPATH and with TransCon CNP under U.S. FDA priority review, Ascendis is on the verge of bringing our third high-value medicine to patients and substantially transforming our financial profile,” said Jan Mikkelsen, Ascendis Pharma's President and Chief Executive Officer.
Ascendis Pharma Reports Second Quarter 2025 Financial Results
Neutral
GlobeNewsWire
1 month ago
Ascendis Pharma to Report Second Quarter 2025 Financial Results and Provide Business Update on August 7, 2025
COPENHAGEN, Denmark, July 31, 2025 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced it will report second quarter 2025 financial results and provide a business update on Thursday, August 7, 2025, after the close of the U.S. financial markets. Ascendis Pharma will also host a conference call and live webcast on August 7, 2025, at 4:30 p.m.
Ascendis Pharma to Report Second Quarter 2025 Financial Results and Provide Business Update on August 7, 2025
Neutral
GlobeNewsWire
1 month ago
FDA Approves SKYTROFA® (Lonapegsomatropin-tcgd) for the Once-Weekly Treatment of Adults with Growth Hormone Deficiency
First of many planned label expansions supporting Vision 2030 goal to become the leading endocrinology rare disease company On track to initiate basket trial for ISS, SHOX deficiency, Turner syndrome, and SGA*, as well as combination therapy trials in achondroplasia and hypochondroplasia, in Q4 2025 COPENHAGEN, Denmark, July 28, 2025 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced that the U.S. Food & Drug Administration (FDA) has approved SKYTROFA® (lonapegsomatropin-tcgd; developed as TransCon hGH) for the replacement of endogenous growth hormone in adults with growth hormone deficiency (GHD), a rare disorder resulting from decreased or total loss of growth hormone production. Lonapegsomatropin (approved by the FDA in 2021 for the treatment of pediatric GHD) is a prodrug of somatropin (human growth hormone, or hGH) administered once weekly, providing sustained release of active, unmodified somatropin.
FDA Approves SKYTROFA® (Lonapegsomatropin-tcgd) for the Once-Weekly Treatment of Adults with Growth Hormone Deficiency
Positive
Zacks Investment Research
2 months ago
Wall Street Analysts Believe Ascendis Pharma (ASND) Could Rally 29.83%: Here's is How to Trade
The average of price targets set by Wall Street analysts indicates a potential upside of 29.8% in Ascendis Pharma (ASND). While the effectiveness of this highly sought-after metric is questionable, the positive trend in earnings estimate revisions might translate into an upside in the stock.
Wall Street Analysts Believe Ascendis Pharma (ASND) Could Rally 29.83%: Here's is How to Trade
Neutral
GlobeNewsWire
2 months ago
New 3-Year Phase 3 Data Confirmed Sustained Response to TransCon® PTH (Palopegteriparatide) Therapy in Adults with Hypoparathyroidism, Including Improvements in Biochemistries, Kidney Function, and Quality of Life
COPENHAGEN, Denmark, July 14, 2025 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced new data from Week 156 of its Phase 3 PaTHway Trial confirming that long-term treatment with TransCon PTH (palopegteriparatide) continued to provide a durable response in adults with hypoparathyroidism regardless of its cause (post-surgical, autoimmune, genetic, or idiopathic), including improvements in biochemistries, kidney function, and quality of life. Results were shared over the weekend in an oral presentation by Aliya Khan, M.D.
New 3-Year Phase 3 Data Confirmed Sustained Response to TransCon® PTH (Palopegteriparatide) Therapy in Adults with Hypoparathyroidism, Including Improvements in Biochemistries, Kidney Function, and Quality of Life
Neutral
GlobeNewsWire
2 months ago
Ascendis to Share Its Latest Endocrinology Rare Disease Data at ENDO 2025
COPENHAGEN, Denmark, July 07, 2025 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced two oral presentations at ENDO 2025, the annual meeting of the Endocrine Society being held July 12-15, 2025, in San Francisco. Dr. Aliya Khan will present new data from Week 156 of the Company's Phase 3 PaTHway Trial demonstrating the safety and efficacy of long-term treatment with TransCon® PTH (palopegteriparatide) in adults with hypoparathyroidism – including maintenance of serum and urine biochemistries within normal levels and sustained improvement in renal function. Dr. Carlos Bacino will present additional safety and tolerability data from Week 52 of the Company's pivotal ApproaCH Trial of once-weekly TransCon® CNP (navepegritide) in children with achondroplasia.
Ascendis to Share Its Latest Endocrinology Rare Disease Data at ENDO 2025
Neutral
GlobeNewsWire
3 months ago
TransCon® hGH Boosted Treatment Benefits of TransCon® CNP in Children with Achondroplasia at Week 26 Interim Analysis of the Phase 2 COACH Trial
- For the TransCon CNP treatment-naïve cohort, combination treatment resulted in mean annualized growth velocity (AGV) of 9.14 cm/year, with an improvement in mean ACH height Z-score of +0.53 over 26 weeks - For the TransCon CNP-treated cohort, combination treatment resulted in mean AGV of 8.25 cm/year, with an improvement in mean ACH height Z-score of +0.44 over 26 weeks - The combination of TransCon hGH and TransCon CNP demonstrated accelerated improvement in body proportionality at Week 26, aligning with the increase in linear growth - Safety and tolerability data consistent with those observed for TransCon hGH and TransCon CNP monotherapies; combination treatment was generally well tolerated, with generally mild treatment-emergent adverse events (TEAEs) - Ascendis to host conference call today at 8:00 am ET COPENHAGEN, Denmark, June 09, 2025 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced Week 26 interim analysis results from its ongoing COACH Trial, the first clinical trial to evaluate combination treatment with once-weekly investigational TransCon CNP (navepegritide) and once-weekly TransCon hGH (lonapegsomatropin) in children with achondroplasia. Results demonstrated that TransCon hGH boosted treatment benefits of TransCon CNP, resulting in significant growth and proportionality improvements in children with achondroplasia after 26 weeks of combination treatment, with a safety and tolerability profile consistent with those observed for TransCon hGH and TransCon CNP monotherapies.
TransCon® hGH Boosted Treatment Benefits of TransCon® CNP in Children with Achondroplasia at Week 26 Interim Analysis of the Phase 2 COACH Trial
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