|
26
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$707M
|
-$72.9M
|
4
|
1.21%
|
Reduced
|
|
|
27
|
ARK Investment Management
St. Petersburg,
Florida
|
$667M
|
+$11.4M
|
5
|
5.1%
|
Increased
|
|
|
28
|
Bank of New York Mellon
New York
|
$662M
|
-$38.3M
|
58
|
0.15%
|
Reduced
|
|
|
29
|
RA Capital Management
Boston,
Massachusetts
|
$569M
|
+$55.5M
|
6
|
11.2%
|
Increased
|
|
|
30
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$506M
|
-$5.98M
|
2
|
11.29%
|
Reduced
|
|
|
31
|
|
$487M
|
-$48.5M
|
41
|
0.13%
|
Reduced
|
|
|
32
|
|
$469M
|
-$121M
|
20
|
0.1%
|
Reduced
|
|
|
33
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$468M
|
-$11.7M
|
24
|
1.25%
|
Reduced
|
|
|
34
|
Renaissance Technologies
New York
|
$435M
|
+$42.9M
|
62
|
0.74%
|
Increased
|
|
|
35
|
ClearBridge Investments
New York
|
$424M
|
-$19.4M
|
3
|
0.41%
|
Reduced
|
|
|
36
|
Barclays
London,
United Kingdom
|
$422M
|
+$107M
|
56
|
0.26%
|
Increased
|
|
|
37
|
Redmile Group
San Francisco,
California
|
$409M
|
-$76.2M
|
11
|
19.44%
|
Reduced
|
|
|
38
|
Citadel Advisors
Miami,
Florida
|
$396M
|
+$38.1M
|
62
|
0.08%
|
Increased
|
|
|
39
|
Adage Capital Partners
Boston,
Massachusetts
|
$391M
|
+$31.9M
|
20
|
0.89%
|
Increased
|
|
|
40
|
Wells Fargo
San Francisco,
California
|
$380M
|
-$6.14M
|
89
|
0.11%
|
Reduced
|
|
|
41
|
Ameriprise
Minneapolis,
Minnesota
|
$377M
|
+$75.3M
|
30
|
0.12%
|
Increased
|
|
|
42
|
Pictet Asset Management
Carouge,
Switzerland
|
$370M
|
+$400M
|
16
|
0.46%
|
New
|
|
|
43
|
AllianceBernstein
Nashville,
Tennessee
|
$365M
|
-$33.6M
|
40
|
0.16%
|
Reduced
|
|
|
44
|
Perceptive Advisors
New York
|
$364M
|
+$3.85M
|
8
|
12.13%
|
Increased
|
|
|
45
|
Sumitomo Mitsui Trust Group
Minato-Ku, Tokyo,
Japan
|
$358M
|
+$8.61M
|
7
|
0.29%
|
Increased
|
|
|
46
|
Kayne Anderson Rudnick Investment Management
Los Angeles,
California
|
$344M
|
+$13.2M
|
4
|
0.98%
|
Increased
|
|
|
47
|
Principal Financial Group
Des Moines,
Iowa
|
$335M
|
+$20.7M
|
33
|
0.24%
|
Increased
|
|
|
48
|
UBS Group
Zurich,
Switzerland
|
$334M
|
+$28M
|
81
|
0.12%
|
Increased
|
|
|
49
|
|
$322M
|
-$35.2M
|
10
|
35.6%
|
Reduced
|
|
|
50
|
Allspring Global Investments
Charlotte,
North Carolina
|
$317M
|
-$10.6M
|
28
|
0.56%
|
Reduced
|
|