|
26
|
Bank of New York Mellon
New York
|
$681M
|
-$19.5M
|
60
|
0.15%
|
Reduced
|
|
|
27
|
EcoR1 Capital
San Francisco,
California
|
$676M
|
-$13.6M
|
10
|
21.75%
|
Reduced
|
|
|
28
|
|
$635M
|
+$118M
|
23
|
0.14%
|
Increased
|
|
|
29
|
Artisan Partners
Milwaukee,
Wisconsin
|
$627M
|
+$53.1M
|
4
|
1.03%
|
Increased
|
|
|
30
|
|
$612M
|
-$11M
|
36
|
0.17%
|
Reduced
|
|
|
31
|
Capital International Investors
Los Angeles,
California
|
$595M
|
+$112M
|
8
|
0.15%
|
Increased
|
|
|
32
|
Millennium Management
New York
|
$575M
|
+$54.9M
|
69
|
0.33%
|
Increased
|
|
|
33
|
American Century Companies
Kansas City,
Missouri
|
$571M
|
+$110M
|
23
|
0.45%
|
Increased
|
|
|
34
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$526M
|
-$23.9M
|
31
|
1.32%
|
Reduced
|
|
|
35
|
Kohlberg Kravis Roberts & Co
New York
|
$515M
|
$0
|
1
|
15.5%
|
Maintained
|
|
|
36
|
Redmile Group
San Francisco,
California
|
$503M
|
+$74.8M
|
13
|
21.81%
|
Increased
|
|
|
37
|
Renaissance Technologies
New York
|
$496M
|
-$30.9M
|
73
|
0.66%
|
Reduced
|
|
|
38
|
|
$460M
|
+$29M
|
9
|
37.92%
|
Increased
|
|
|
39
|
Point72 Asset Management
Stamford,
Connecticut
|
$458M
|
+$102M
|
32
|
1.42%
|
Increased
|
|
|
40
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$458M
|
+$153M
|
18
|
0.57%
|
Increased
|
|
|
41
|
Veritas Asset Management
London,
United Kingdom
|
$452M
|
-$265M
|
1
|
3.34%
|
Reduced
|
|
|
42
|
AllianceBernstein
Nashville,
Tennessee
|
$452M
|
+$68.3M
|
37
|
0.19%
|
Increased
|
|
|
43
|
Marshall Wace
London,
United Kingdom
|
$417M
|
+$89.6M
|
25
|
0.89%
|
Increased
|
|
|
44
|
ClearBridge Investments
New York
|
$393M
|
+$6.81M
|
3
|
0.38%
|
Increased
|
|
|
45
|
Citadel Advisors
Miami,
Florida
|
$388M
|
+$49.7M
|
66
|
0.09%
|
Increased
|
|
|
46
|
Sumitomo Mitsui Trust Group
Minato-Ku, Tokyo,
Japan
|
$376M
|
-$48.8K
|
7
|
0.28%
|
Reduced
|
|
|
47
|
Wells Fargo
San Francisco,
California
|
$365M
|
+$36.8M
|
96
|
0.11%
|
Increased
|
|
|
48
|
Nuveen
Charlotte,
North Carolina
|
$344M
|
+$34.6M
|
37
|
0.13%
|
Increased
|
|
|
49
|
Ameriprise
Minneapolis,
Minnesota
|
$342M
|
-$10.4M
|
29
|
0.11%
|
Reduced
|
|
|
50
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$338M
|
-$23.1M
|
47
|
0.19%
|
Reduced
|
|