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GeneDx Holdings
WGS

286 hedge funds and large institutions have $4.03B invested in GeneDx Holdings in 2025 Q4 according to their latest regulatory filings, with 59 funds opening new positions, 92 increasing their positions, 101 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

55% more first-time investments, than exits

New positions opened: 59 | Existing positions closed: 38

24% more capital invested

Capital invested by funds: $3.24B → $4.03B (+$784M)

9% more funds holding in top 10

Funds holding in top 10: 11 → 12 (+1)

7% more funds holding

Funds holding: 268 → 286 (+18)

2.42% more ownership

Funds ownership: 104.79% → 107.22% (+2.4%)

6% less call options, than puts

Call options by funds: $102M | Put options by funds: $108M

9% less repeat investments, than reductions

Existing positions increased: 92 | Existing positions reduced: 101

Holders
286
Holders Change
+18
Holders Change %
+6.72%
% of All Funds
3.48%
Holding in Top 10
12
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+9.09%
% of All Funds
0.15%
New
59
Increased
92
Reduced
101
Closed
38
Calls
$102M
Puts
$108M
Net Calls
-$5.95M
Net Calls Change
+$36.2M

Top Buyers

1
Westfield Capital Management
Westfield Capital Management
Massachusetts
+$65.1M
2
Franklin Resources
Franklin Resources
California
+$56.5M
3
Fidelity Investments
Fidelity Investments
Massachusetts
+$45.2M
4
Invesco
Invesco
Georgia
+$40.1M
5
UBS AM
UBS AM
Illinois
+$31.2M

Top Sellers

1
William Blair Investment Management
William Blair Investment Management
Illinois
-$56.4M
2
PCM
Pentwater Capital Management
Florida
-$51.5M
3
Jennison Associates
Jennison Associates
New York
-$40.7M
4
Macquarie Group
Macquarie Group
Australia
-$29M
5
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
-$18.4M
Name Holding Trade Value Shares
Change 		Change in
Stake
MAM
101
Morse Asset Management
Connecticut
$3.28M -$306K -2,226 -8%
Two Sigma Investments
102
Two Sigma Investments
New York
$3.25M -$14.5M -105,459 -81%
Mirae Asset Global ETFs Holdings
103
Mirae Asset Global ETFs Holdings
Hong Kong
$3.25M -$47.8K -348 -1%
AQR Capital Management
104
AQR Capital Management
Connecticut
$3.21M -$558K -4,068 -14%
Manulife (Manufacturers Life Insurance)
105
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$3.21M +$398K +2,903 +13%
EI
106
EAM Investors
California
$3.15M +$770K +5,611 +30%
RhumbLine Advisers
107
RhumbLine Advisers
Massachusetts
$3.08M -$539K -3,925 -14%
AI
108
Alphabet Inc
California
$2.95M – – –
National Bank of Canada
109
National Bank of Canada
Quebec, Canada
$2.86M – – –
SCM
110
Steadfast Capital Management
New York
$2.86M +$3.02M +22,000 New
Royal Bank of Canada
111
Royal Bank of Canada
Ontario, Canada
$2.74M -$461K -3,360 -14%
MCP
112
Meridiem Capital Partners
Texas
$2.71M +$2.86M +20,807 New
Legal & General Group
113
Legal & General Group
United Kingdom
$2.64M +$211K +1,535 +8%
California State Teachers Retirement System (CalSTRS)
114
California State Teachers Retirement System (CalSTRS)
California
$2.48M -$261K -1,899 -9%
Squarepoint
115
Squarepoint
New York
$2.48M -$8.07M -58,809 -76%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
116
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$2.41M -$9.88M -72,000 -80%
Envestnet Asset Management
117
Envestnet Asset Management
Illinois
$2.36M +$110K +798 +5%
HA
118
Huntleigh Advisors
Missouri
$2.34M +$60.8K +443 +3%
CP
119
CenterBook Partners
Connecticut
$2.33M +$2.46M +17,893 New
SSA
120
Schonfeld Strategic Advisors
New York
$2.25M +$592K +4,311 +33%
VAS
121
Vestmark Advisory Solutions
Massachusetts
$2.22M -$35.7K -260 -2%
Deutsche Bank
122
Deutsche Bank
Germany
$2.15M +$66.2K +482 +3%
QT
123
Quantbot Technologies
New York
$2.07M +$2.18M +15,918 New
MMEA
124
Main Management ETF Advisors
California
$2.04M +$22K +160 +1%
D.E. Shaw & Co
125
D.E. Shaw & Co
New York
$2.03M +$2.14M +15,603 New
3 4
5
6 7

WGS Hedge Fund Activity: Q4 2025 in Review

286 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in GeneDx Holdings (WGS) for Q4 2025, worth a combined $4.03B — up 24% from $3.24B a quarter earlier.

Buyers outnumbered sellers: 59 funds opened new WGS positions and 38 closed out — a net gain of 21 holders — while 92 added to existing stakes and 101 trimmed.

The largest buyer was Westfield Capital Management, adding an estimated $65.1M. The largest seller was William Blair Investment Management, cutting an estimated $56.4M.

  • 286 institutional investors held GeneDx Holdings (WGS) as of Q4 2025, up from 268 in Q3 2025.
  • Funds reported $4.03B of GeneDx Holdings stock for Q4 2025, up 24% quarter-over-quarter.
  • 59 funds opened new GeneDx Holdings positions in Q4 2025 and 38 closed out, a net change of +21 holders.
  • The largest GeneDx Holdings buyer in Q4 2025 was Westfield Capital Management, an estimated $65.1M added.
  • The largest GeneDx Holdings seller in Q4 2025 was William Blair Investment Management, an estimated $56.4M sold.

Based on aggregated 13F filings for Q4 2025.