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GeneDx Holdings
WGS

286 hedge funds and large institutions have $4.03B invested in GeneDx Holdings in 2025 Q4 according to their latest regulatory filings, with 59 funds opening new positions, 92 increasing their positions, 101 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

55% more first-time investments, than exits

New positions opened: 59 | Existing positions closed: 38

24% more capital invested

Capital invested by funds: $3.24B → $4.03B (+$784M)

9% more funds holding in top 10

Funds holding in top 10: 11 → 12 (+1)

7% more funds holding

Funds holding: 268 → 286 (+18)

2.42% more ownership

Funds ownership: 104.79% → 107.22% (+2.4%)

6% less call options, than puts

Call options by funds: $102M | Put options by funds: $108M

9% less repeat investments, than reductions

Existing positions increased: 92 | Existing positions reduced: 101

Holders
286
Holders Change
+18
Holders Change %
+6.72%
% of All Funds
3.48%
Holding in Top 10
12
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+9.09%
% of All Funds
0.15%
New
59
Increased
92
Reduced
101
Closed
38
Calls
$102M
Puts
$108M
Net Calls
-$5.95M
Net Calls Change
+$36.2M

Top Buyers

1
Westfield Capital Management
Westfield Capital Management
Massachusetts
+$65.1M
2
Franklin Resources
Franklin Resources
California
+$56.5M
3
Fidelity Investments
Fidelity Investments
Massachusetts
+$45.2M
4
Invesco
Invesco
Georgia
+$40.1M
5
UBS AM
UBS AM
Illinois
+$31.2M

Top Sellers

1
William Blair Investment Management
William Blair Investment Management
Illinois
-$56.4M
2
PCM
Pentwater Capital Management
Florida
-$51.5M
3
Jennison Associates
Jennison Associates
New York
-$40.7M
4
Macquarie Group
Macquarie Group
Australia
-$29M
5
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
-$18.4M
Name Holding Trade Value Shares
Change 		Change in
Stake
PIP
51
Palisades Investment Partners
California
$11.3M +$332K +2,421 +3%
Principal Financial Group
52
Principal Financial Group
Iowa
$10.7M +$3.07M +22,339 +37%
VOYA Investment Management
53
VOYA Investment Management
Georgia
$10.4M -$5.16M -37,615 -32%
RA
54
Royce & Associates
New York
$9.86M -$3.76M -27,416 -27%
Qube Research & Technologies (QRT)
55
Qube Research & Technologies (QRT)
United Kingdom
$9.81M +$7.93M +57,809 +328%
Russell Investments Group
56
Russell Investments Group
United Kingdom
$9.74M -$556K -4,052 -5%
CM
57
Castleark Management
Illinois
$9.63M +$306K +2,230 +3%
Ensign Peak Advisors
58
Ensign Peak Advisors
Utah
$9.5M -$820K -5,974 -8%
FCM
59
Farallon Capital Management
California
$9.1M +$8.92M +65,000 +1,300%
AI
60
Axiom Investors
Connecticut
$8.96M +$9.45M +68,855 New
Norges Bank
61
Norges Bank
Norway
$8.84M +$9.33M +68,000 New
Millennium Management
62
Millennium Management
New York
$8.58M +$1.95M +14,217 +27%
SG Americas Securities
63
SG Americas Securities
New York
$8.22M +$7.84M +57,090 +937%
TI
64
Trexquant Investment
Connecticut
$8.09M +$3.8M +27,720 +80%
First Trust Advisors
65
First Trust Advisors
Illinois
$8.07M -$282K -2,051 -3%
SAM
66
Silvercrest Asset Management
New York
$8.05M +$16.6K +121 +0.2%
Impax Asset Management Group
67
Impax Asset Management Group
United Kingdom
$7.8M +$1.37M +10,000 +20%
Polen Capital Management
68
Polen Capital Management
Florida
$7.79M -$1.14M -8,308 -12%
LAI
69
Legal Advantage Investments
California
$7.76M -$137K -1,000 -2%
BNP Paribas Asset Management
70
BNP Paribas Asset Management
France
$7.6M +$8M +58,271 +31,161%
RCM
71
RA Capital Management
Massachusetts
$7.55M – – –
Renaissance Technologies
72
Renaissance Technologies
New York
$7.45M +$7.87M +57,316 New
PCM
73
Portolan Capital Management
Massachusetts
$7.25M +$1.61M +11,728 +27%
RG
74
Renaissance Group
Kentucky
$7.17M +$7.56M +55,103 New
AAP
75
Ardsley Advisory Partners
Connecticut
$7.15M -$686K -5,000 -8%
1 2
3
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WGS Hedge Fund Activity: Q4 2025 in Review

286 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in GeneDx Holdings (WGS) for Q4 2025, worth a combined $4.03B — up 24% from $3.24B a quarter earlier.

Buyers outnumbered sellers: 59 funds opened new WGS positions and 38 closed out — a net gain of 21 holders — while 92 added to existing stakes and 101 trimmed.

The largest buyer was Westfield Capital Management, adding an estimated $65.1M. The largest seller was William Blair Investment Management, cutting an estimated $56.4M.

  • 286 institutional investors held GeneDx Holdings (WGS) as of Q4 2025, up from 268 in Q3 2025.
  • Funds reported $4.03B of GeneDx Holdings stock for Q4 2025, up 24% quarter-over-quarter.
  • 59 funds opened new GeneDx Holdings positions in Q4 2025 and 38 closed out, a net change of +21 holders.
  • The largest GeneDx Holdings buyer in Q4 2025 was Westfield Capital Management, an estimated $65.1M added.
  • The largest GeneDx Holdings seller in Q4 2025 was William Blair Investment Management, an estimated $56.4M sold.

Based on aggregated 13F filings for Q4 2025.