Ventyx Biosciences
VTYX
VTYX was delisted on the 3rd of March, 2026.
139 hedge funds and large institutions have $472M invested in Ventyx Biosciences in 2025 Q4 according to their latest regulatory filings, with 51 funds opening new positions, 30 increasing their positions, 41 reducing their positions, and 22 closing their positions.
246% more capital invested
Capital invested by funds: $136M → $472M (+$335M)
132% more first-time investments, than exits
New positions opened: 51 | Existing positions closed: 22
26% more funds holding
Funds holding: 110 → 139 (+29)
11.69% more ownership
Funds ownership: 61.5% → 73.19% (+12%)
27% less repeat investments, than reductions
Existing positions increased: 30 | Existing positions reduced: 41
73% less call options, than puts
Call options by funds: $6.55M | Put options by funds: $23.8M
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Morgan Stanley
New York
|
+$30.3M |
| 2 |
AAA
Affinity Asset Advisors
New York
|
+$19.1M |
| 3 |
BlackRock
New York
|
+$14.6M |
| 4 |
B
Braidwell
Stamford,
Connecticut
|
+$14.4M |
| 5 |
MB
MPM BioImpact
Boston,
Massachusetts
|
+$12.2M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Point72 Asset Management
Stamford,
Connecticut
|
-$16.1M |
| 2 |
SAM
Sectoral Asset Management
Montreal,
Quebec, Canada
|
-$7.55M |
| 3 |
Marshall Wace
London,
United Kingdom
|
-$7.2M |
| 4 |
VPC
Vestal Point Capital
New York
|
-$6.38M |
| 5 |
JP Morgan Chase
New York
|
-$5.55M |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
WP
151
Woodline Partners
San Francisco,
California
| – | -$143K | -45,826 | Closed |
|
|
PCM
152
Prelude Capital Management
New York
| – | -$65.9K | -21,200 | Closed |
|
|
SFI
153
Susquehanna Fundamental Investments
Bala Cynwyd,
Pennsylvania
| – | -$64.6K | -20,777 | Closed |
|
154
Jacobs Levy Equity Management
Florham Park,
New Jersey
| – | -$60.9K | -19,577 | Closed |
|
|
FIA
155
FNY Investment Advisers
New York
| – | -$15K | -5,000 | Closed |
|
|
RA
156
Rise Advisors
Rochester,
New York
| – | -$2.71K | -870 | Closed |
|
|
WANY
157
Wealthspire Advisors (New York)
New York
| – | -$2.63K | -844 | Closed |
|
|
EP
158
Essential Partners
Rancho Santa Fe,
California
| – | -$896 | -288 | Closed |
|
|
FFA
159
Farther Finance Advisors
San Francisco,
California
| – | -$311 | -100 | Closed |
|
160
Osaic Holdings
Scottsdale,
Arizona
| – | -$190 | -61 | Closed |
|
|
IA
161
IFP Advisors
Tampa,
Florida
| – | -$16 | -5 | Closed |
|
VTYX Hedge Fund Activity: Q4 2025 in Review
139 of the 8,226 institutional investors tracked by Wall St. Rank reported a position in Ventyx Biosciences (VTYX) for Q4 2025, worth a combined $472M — up 246% from $136M a quarter earlier.
Buyers outnumbered sellers: 51 funds opened new VTYX positions and 22 closed out — a net gain of 29 holders — while 30 added to existing stakes and 41 trimmed.
The largest buyer was Morgan Stanley, adding an estimated $30.3M. The largest seller was Point72 Asset Management, cutting an estimated $16.1M.
- 139 institutional investors held Ventyx Biosciences (VTYX) as of Q4 2025, up from 110 in Q3 2025.
- Funds reported $472M of Ventyx Biosciences stock for Q4 2025, up 246% quarter-over-quarter.
- 51 funds opened new Ventyx Biosciences positions in Q4 2025 and 22 closed out, a net change of +29 holders.
- The largest Ventyx Biosciences buyer in Q4 2025 was Morgan Stanley, an estimated $30.3M added.
- The largest Ventyx Biosciences seller in Q4 2025 was Point72 Asset Management, an estimated $16.1M sold.
Based on aggregated 13F filings for Q4 2025.