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Vor Biopharma
VOR

55 hedge funds and large institutions have $332M invested in Vor Biopharma in 2025 Q4 according to their latest regulatory filings, with 28 funds opening new positions, 19 increasing their positions, 2 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

850% more repeat investments, than reductions

Existing positions increased: 19 | Existing positions reduced: 2

242.42% more ownership

Funds ownership: 2.97% → 245.39% (+242%)

180% more first-time investments, than exits

New positions opened: 28 | Existing positions closed: 10

173% more call options, than puts

Call options by funds: $16.2M | Put options by funds: $5.93M

81% more capital invested

Capital invested by funds: $183M → $332M (+$149M)

49% more funds holding

Funds holding: 37 → 55 (+18)

33% more funds holding in top 10

Funds holding in top 10: 3 → 4 (+1)

Holders
55
Holders Change
+18
Holders Change %
+48.65%
% of All Funds
0.67%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
28
Increased
19
Reduced
2
Closed
10
Calls
$16.2M
Puts
$5.93M
Net Calls
+$10.3M
Net Calls Change
-$293M

Top Buyers

Rank Fund Capital Flow
1
RCM
RA Capital Management
Massachusetts
+$63.7M
2
FIS
FCPM III Services
Netherlands
+$60.3M
3
FLSM
Frazier Life Sciences Management
California
+$47.4M
4
Fidelity Investments
Fidelity Investments
Massachusetts
+$42.6M
5
PBA
Paradigm Biocapital Advisors
New York
+$32.6M

Top Sellers

Rank Fund Capital Flow
1
ACM
Ariose Capital Management
Hong Kong
-$5.37M
2
TCM
Tang Capital Management
California
-$2.44M
3
WP
Woodline Partners
California
-$1.33M
4
PCMH
Polymer Capital Management (HK)
Hong Kong
-$1.04M
5
Renaissance Technologies
Renaissance Technologies
New York
-$711K
Name Holding Trade Value Shares
Change 		Change in
Stake
MCM
51
MAI Capital Management
Ohio
$524 – – –
AF
52
Allworth Financial
California
$40 – – –
SS
53
SBI Securities
Japan
$39 – – –
Wells Fargo
54
Wells Fargo
California
$13 – – –
ACM
55
Ariose Capital Management
Hong Kong
– -$5.37M -110,173 Closed
TCM
56
Tang Capital Management
California
– -$2.44M -50,000 Closed
WP
57
Woodline Partners
California
– -$1.33M -27,363 Closed
PCMH
58
Polymer Capital Management (HK)
Hong Kong
– -$1.04M -21,248 Closed
Renaissance Technologies
59
Renaissance Technologies
New York
– -$711K -14,600 Closed
VF
60
Virtu Financial
New York
– -$395K -8,104 Closed
BCM
61
Bridgeway Capital Management
Texas
– -$305K -6,250 Closed
SRL
62
Scientech Research LLC
New Jersey
– -$297K -6,097 Closed
TOCUITCONY
63
Trustees of Columbia University in the City of New York
New York
– -$224K -4,595 Closed
CIAM
64
Caitong International Asset Management
Hong Kong
– -$5.36K -110 Closed
Royal Bank of Canada
65
Royal Bank of Canada
Ontario, Canada
– +$93 +5 +250%
1 2
3

VOR Hedge Fund Activity: Q4 2025 in Review

55 of the 8,244 institutional investors tracked by Wall St. Rank reported a position in Vor Biopharma (VOR) for Q4 2025, worth a combined $332M — up 81% from $183M a quarter earlier.

Buyers outnumbered sellers: 28 funds opened new VOR positions and 10 closed out — a net gain of 18 holders — while 19 added to existing stakes and 2 trimmed.

The largest buyer was RA Capital Management, adding an estimated $63.7M. The largest seller was Ariose Capital Management, exiting entirely with an estimated $5.37M sold.

  • 55 institutional investors held Vor Biopharma (VOR) as of Q4 2025, up from 37 in Q3 2025.
  • Funds reported $332M of Vor Biopharma stock for Q4 2025, up 81% quarter-over-quarter.
  • 28 funds opened new Vor Biopharma positions in Q4 2025 and 10 closed out, a net change of +18 holders.
  • The largest Vor Biopharma buyer in Q4 2025 was RA Capital Management, an estimated $63.7M added.
  • The largest Vor Biopharma seller in Q4 2025 was Ariose Capital Management, an estimated $5.37M sold.

Based on aggregated 13F filings for Q4 2025.