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10x Genomics
TXG

317 hedge funds and large institutions have $1.44B invested in 10x Genomics in 2025 Q3 according to their latest regulatory filings, with 66 funds opening new positions, 98 increasing their positions, 91 reducing their positions, and 42 closing their positions.

New
Increased
Maintained
Reduced
Closed

113% more call options, than puts

Call options by funds: $5.96M | Put options by funds: $2.8M

100% more funds holding in top 10

Funds holding in top 10: 1 → 2 (+1)

57% more first-time investments, than exits

New positions opened: 66 | Existing positions closed: 42

7% more funds holding

Funds holding: 297 → 317 (+20)

8% more repeat investments, than reductions

Existing positions increased: 98 | Existing positions reduced: 91

1% more capital invested

Capital invested by funds: $1.42B → $1.44B (+$16.6M)

2.94% less ownership

Funds ownership: 110.37% → 107.43% (-2.9%)

Holders
317
Holders Change
+20
Holders Change %
+6.73%
% of All Funds
4.16%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
66
Increased
98
Reduced
91
Closed
42
Calls
$5.96M
Puts
$2.8M
Net Calls
+$3.16M
Net Calls Change
+$1.32M

Top Buyers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
+$33.3M
2
Wellington Management Group
Wellington Management Group
Massachusetts
+$31.2M
3
Goldman Sachs
Goldman Sachs
New York
+$27M
4
QCM
Quantinno Capital Management
New York
+$16.4M
5
Royal Bank of Canada
Royal Bank of Canada
Ontario, Canada
+$16M

Top Sellers

Rank Fund Capital Flow
1
AIM
ARK Investment Management
Florida
-$26.1M
2
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
-$22.1M
3
AQR Capital Management
AQR Capital Management
Connecticut
-$18.4M
4
BWLSA
Blue Water Life Science Advisors
California
-$12.7M
5
JF
Jump Financial
Illinois
-$12.5M
Name Holding Trade Value Shares
Change 		Change in
Stake
RTL
276
Red Tortoise LLC
Georgia
$2.54K – – –
EWP
277
Elevation Wealth Partners
California
$2.5K +$2.79K +214 New
CAL
278
Capital Advisors Ltd
Ohio
$2K – – –
PS
279
Principal Securities
Iowa
$1.87K -$1.25K -96 -38%
SS
280
Sunbelt Securities
Texas
$1.78K +$1.98K +152 New
TPCW
281
TD Private Client Wealth
New York
$1.73K +$1.93K +148 New
CWM
282
Copia Wealth Management
Oregon
$1.64K +$1.82K +140 New
SPIA
283
Steward Partners Investment Advisory
New York
$1.63K +$509 +39 +39%
Mitsubishi UFJ Asset Management
284
Mitsubishi UFJ Asset Management
Japan
$1.45K – – –
JFGIW
285
Johnson Financial Group Inc (Wisconsin)
Wisconsin
$1.39K +$1.55K +119 New
RA
286
Rise Advisors
New York
$1.33K – – –
BGAI
287
Bruce G. Allen Investments
Colorado
$1.32K – – –
WANY
288
Wealthspire Advisors (New York)
New York
$1.17K +$1.3K +100 New
SAM
289
Smartleaf Asset Management
Massachusetts
$1.09K +$1.25K +96 New
BFS
290
Bare Financial Services
Pennsylvania
$1.09K – – –
MCM
291
MAI Capital Management
Ohio
$1.02K -$5.37K -412 -83%
BTI
292
Blue Trust Inc
Georgia
$935 -$62.8K -4,814 -98%
ASN
293
Advisory Services Network
Georgia
$912 +$1.02K +78 New
BIA
294
Bell Investment Advisors
California
$877 – – –
RWM
295
Rialto Wealth Management
New York
$702 – – –
TFM
296
TFC Financial Management
Massachusetts
$655 – – –
DJSG
297
D.J. St. Germain
Massachusetts
$608 – – –
ADL
298
Asset Dedication LLC
California
$597 – – –
GWSG
299
GPS Wealth Strategies Group
Colorado
$585 – – –
NEWAS
300
N.E.W. Advisory Services
Wisconsin
$585 – – –
10 11
12
13 14

TXG Hedge Fund Activity: Q3 2025 in Review

317 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in 10x Genomics (TXG) for Q3 2025, worth a combined $1.44B — up 1.2% from $1.42B a quarter earlier.

Buyers outnumbered sellers: 66 funds opened new TXG positions and 42 closed out — a net gain of 24 holders — while 98 added to existing stakes and 91 trimmed.

The largest buyer was Millennium Management, adding an estimated $33.3M. The largest seller was ARK Investment Management, cutting an estimated $26.1M.

  • 317 institutional investors held 10x Genomics (TXG) as of Q3 2025, up from 297 in Q2 2025.
  • Funds reported $1.44B of 10x Genomics stock for Q3 2025, up 1.2% quarter-over-quarter.
  • 66 funds opened new 10x Genomics positions in Q3 2025 and 42 closed out, a net change of +24 holders.
  • The largest 10x Genomics buyer in Q3 2025 was Millennium Management, an estimated $33.3M added.
  • The largest 10x Genomics seller in Q3 2025 was ARK Investment Management, an estimated $26.1M sold.

Based on aggregated 13F filings for Q3 2025.