We are live on ! Find out more
TSVT

2seventy bio
TSVT

Delisted

TSVT was delisted on the 13th of May, 2025.

Back to rankings

133 hedge funds and large institutions have $544M invested in 2seventy bio in 2022 Q1 according to their latest regulatory filings, with 35 funds opening new positions, 35 increasing their positions, 31 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more funds holding in top 10

Funds holding in top 10: 1 → 3 (+2)

30% more first-time investments, than exits

New positions opened: 35 | Existing positions closed: 27

13% more capital invested

Capital invested by funds: $479M → $544M (+$64.6M)

13% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 31

5% more funds holding

Funds holding: 127 → 133 (+6)

Holders
133
Holders Change
+6
Holders Change %
+4.72%
% of All Funds
2.1%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.05%
New
35
Increased
35
Reduced
31
Closed
27
Calls
$395K
Puts
–
Net Calls
+$395K
Net Calls Change
-$226K

Top Buyers

Rank Fund Capital Flow
1
EC
EcoR1 Capital
California
+$26.8M
2
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
+$20.9M
3
BBA
Baker Bros. Advisors
New York
+$20.9M
4
RI
RTW Investments
New York
+$20.9M
5
AC
Armistice Capital
New York
+$19.4M

Top Sellers

Rank Fund Capital Flow
1
Vanguard Group
Vanguard Group
Pennsylvania
-$8.14M
2
Goldman Sachs
Goldman Sachs
New York
-$6.64M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
-$4.68M
4
PAMS
Pictet Asset Management (Switzerland)
Switzerland
-$1.99M
5
Principal Financial Group
Principal Financial Group
Iowa
-$1.98M
Name Holding Trade Value Shares
Change 		Change in
Stake
PAMS
126
Pictet Asset Management (Switzerland)
Switzerland
– -$1.99M -77,698 Closed
Principal Financial Group
127
Principal Financial Group
Iowa
– -$1.98M -77,240 Closed
MP
128
Mangrove Partners
Connecticut
– -$1.32M -51,601 Closed
Toronto Dominion Bank
129
Toronto Dominion Bank
Ontario, Canada
– -$1.22M -47,543 Closed
PP
130
PDT Partners
New York
– -$911K -35,543 Closed
N
131
Natixis
France
– -$851K -33,199 Closed
QOP
132
Quinn Opportunity Partners
Virginia
– -$794K -30,985 Closed
Walleye Capital
133
Walleye Capital
New York
– -$592K -23,110 Closed
PI
134
Putnam Investments
Massachusetts
– -$503K -19,646 Closed
Canada Pension Plan Investment Board
135
Canada Pension Plan Investment Board
Ontario, Canada
– -$411K -16,039 Closed
Manulife (Manufacturers Life Insurance)
136
Manulife (Manufacturers Life Insurance)
Ontario, Canada
– -$303 -11,831 Closed
Connor, Clark & Lunn Investment Management (CC&L)
137
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
– -$284K -11,071 Closed
SG Americas Securities
138
SG Americas Securities
New York
– -$281K -10,946 Closed
BJL
139
Brighton Jones LLC
Washington
– -$232K -9,042 Closed
VOYA Investment Management
140
VOYA Investment Management
Georgia
– -$225K -8,761 Closed
Squarepoint
141
Squarepoint
New York
– -$209K -8,165 Closed
EVM
142
Eaton Vance Management
Massachusetts
– -$4K -166 Closed
TWA
143
TCI Wealth Advisors
Arizona
– -$3K -135 Closed
AWM
144
Avior Wealth Management
Nebraska
– -$2K -100 Closed
CLOS
145
Compagnie Lombard Odier SCmA
Switzerland
– -$2K -76 Closed
QCG
146
Quadrant Capital Group
Ohio
– -$237 -14 -52%
HR
147
Howe & Rusling
New York
– -$34 -2 -17%
PA
148
Parallel Advisors
California
– +$237 +14 New
GRP
149
Global Retirement Partners
California
– +$254 +15 New
2 3 4 5
6

TSVT Hedge Fund Activity: Q1 2022 in Review

133 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in 2seventy bio (TSVT) for Q1 2022, worth a combined $544M — up 13% from $479M a quarter earlier.

Buyers outnumbered sellers: 35 funds opened new TSVT positions and 27 closed out — a net gain of 8 holders — while 35 added to existing stakes and 31 trimmed.

The largest buyer was EcoR1 Capital, adding an estimated $26.8M. The largest seller was Vanguard Group, cutting an estimated $8.14M.

  • 133 institutional investors held 2seventy bio (TSVT) as of Q1 2022, up from 127 in Q4 2021.
  • Funds reported $544M of 2seventy bio stock for Q1 2022, up 13% quarter-over-quarter.
  • 35 funds opened new 2seventy bio positions in Q1 2022 and 27 closed out, a net change of +8 holders.
  • The largest 2seventy bio buyer in Q1 2022 was EcoR1 Capital, an estimated $26.8M added.
  • The largest 2seventy bio seller in Q1 2022 was Vanguard Group, an estimated $8.14M sold.

Based on aggregated 13F filings for Q1 2022.