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TSVT

2seventy bio
TSVT

Delisted

TSVT was delisted on the 13th of May, 2025.

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141 hedge funds and large institutions have $317M invested in 2seventy bio in 2022 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 40 increasing their positions, 32 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

148% more call options, than puts

Call options by funds: $500K | Put options by funds: $202K

58% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 19

25% more repeat investments, than reductions

Existing positions increased: 40 | Existing positions reduced: 32

6% more funds holding

Funds holding: 133 → 141 (+8)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

34% less capital invested

Capital invested by funds: $478M → $317M (-$161M)

Holders
141
Holders Change
+8
Holders Change %
+6.02%
% of All Funds
2.27%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
30
Increased
40
Reduced
32
Closed
19
Calls
$500K
Puts
$202K
Net Calls
+$298K
Net Calls Change
-$1.41M

Top Buyers

Rank Fund Capital Flow
1
CC
Casdin Capital
New York
+$17.4M
2
ECM
ExodusPoint Capital Management
New York
+$9.34M
3
Millennium Management
Millennium Management
New York
+$8.45M
4
BlackRock
BlackRock
New York
+$5.99M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$3.27M

Top Sellers

Rank Fund Capital Flow
1
AC
Armistice Capital
New York
-$18.4M
2
RI
RTW Investments
New York
-$17.9M
3
EC
EcoR1 Capital
California
-$16.9M
4
SC
Sessa Capital
New York
-$4.45M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
-$4.1M
Name Holding Trade Value Shares
Change 		Change in
Stake
SAM
101
Shell Asset Management
Netherlands
$43K -$7.91K -561 -11%
AIP
102
Ameritas Investment Partners
Nebraska
$32K – – –
Osaic Holdings
103
Osaic Holdings
Arizona
$31.2K -$607 -43 -1%
Wells Fargo
104
Wells Fargo
California
$27.5K -$30.7K -2,174 -43%
Public Employees Retirement Association of Colorado
105
Public Employees Retirement Association of Colorado
Colorado
$27K – – –
Zurich Cantonal Bank
106
Zurich Cantonal Bank
Switzerland
$23.3K – – –
MLICM
107
Metropolitan Life Insurance Company (MetLife)
New York
$22.5K – – –
Nisa Investment Advisors
108
Nisa Investment Advisors
Missouri
$14K -$663 -47 -3%
TRCT
109
Tower Research Capital (TRC)
New York
$10K -$119K -8,428 -89%
PNC Financial Services Group
110
PNC Financial Services Group
Pennsylvania
$6.13K – – –
CSS
111
Cubist Systematic Strategies
Connecticut
$3.86K -$343K -24,297 -98%
CUAMC
112
China Universal Asset Management Company
China
$3.62K +$5.45K +386 New
HCM
113
Highlander Capital Management
New Jersey
$3K – – –
Baillie Gifford & Co
114
Baillie Gifford & Co
United Kingdom
$2.68K – – –
US Bancorp
115
US Bancorp
Minnesota
$2.51K -$1.19K -84 -24%
ASN
116
Advisory Services Network
Georgia
$2.15K +$3.23K +229 New
HPC
117
HM Payson & Co
Maine
$1.87K -$1.88K -133 -40%
CCA
118
Column Capital Advisors
Indiana
$1.31K – – –
PP
119
PFS Partners
New Jersey
$1.06K +$1.59K +113 New
Daiwa Securities Group
120
Daiwa Securities Group
Japan
$1K +$2.14K +152 New
SPIA
121
Steward Partners Investment Advisory
New York
$993 – – –
MCC
122
Money Concepts Capital
Florida
$834 +$1.25K +89 New
HWM
123
HighMark Wealth Management
Minnesota
$712 – – –
BC
124
Barrett & Company
Rhode Island
$618 – – –
Northwestern Mutual Wealth Management
125
Northwestern Mutual Wealth Management
Wisconsin
$543 – – –
3 4
5
6 7

TSVT Hedge Fund Activity: Q4 2022 in Review

141 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in 2seventy bio (TSVT) for Q4 2022, worth a combined $317M — down 34% from $478M a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new TSVT positions and 19 closed out — a net gain of 11 holders — while 40 added to existing stakes and 32 trimmed.

The largest buyer was Casdin Capital, adding an estimated $17.4M. The largest seller was Armistice Capital, exiting entirely with an estimated $18.4M sold.

  • 141 institutional investors held 2seventy bio (TSVT) as of Q4 2022, up from 133 in Q3 2022.
  • Funds reported $317M of 2seventy bio stock for Q4 2022, down 34% quarter-over-quarter.
  • 30 funds opened new 2seventy bio positions in Q4 2022 and 19 closed out, a net change of +11 holders.
  • The largest 2seventy bio buyer in Q4 2022 was Casdin Capital, an estimated $17.4M added.
  • The largest 2seventy bio seller in Q4 2022 was Armistice Capital, an estimated $18.4M sold.

Based on aggregated 13F filings for Q4 2022.