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TSVT

2seventy bio
TSVT

Delisted

TSVT was delisted on the 13th of May, 2025.

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133 hedge funds and large institutions have $478M invested in 2seventy bio in 2022 Q3 according to their latest regulatory filings, with 17 funds opening new positions, 37 increasing their positions, 36 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

309% more call options, than puts

Call options by funds: $2.26M | Put options by funds: $552K

10% more capital invested

Capital invested by funds: $436M → $478M (+$42.4M)

6% more first-time investments, than exits

New positions opened: 17 | Existing positions closed: 16

3% more repeat investments, than reductions

Existing positions increased: 37 | Existing positions reduced: 36

1% more funds holding

Funds holding: 132 → 133 (+1)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

Holders
133
Holders Change
+1
Holders Change %
+0.76%
% of All Funds
2.29%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
17
Increased
37
Reduced
36
Closed
16
Calls
$2.26M
Puts
$552K
Net Calls
+$1.71M
Net Calls Change
+$1.89M

Top Buyers

Rank Fund Capital Flow
1
O
OrbiMed
New York
+$15.5M
2
Goldman Sachs
Goldman Sachs
New York
+$10.7M
3
PVI
Pura Vida Investments
New York
+$4.82M
4
Wellington Management Group
Wellington Management Group
Massachusetts
+$4.55M
5
Millennium Management
Millennium Management
New York
+$3.47M

Top Sellers

Rank Fund Capital Flow
1
EC
EcoR1 Capital
California
-$17.1M
2
CCM
CAAS Capital Management
New York
-$6.99M
3
NM
Newtyn Management
New York
-$5.89M
4
AC
Armistice Capital
New York
-$4.99M
5
MAP
Madison Avenue Partners
New York
-$4.62M
Name Holding Trade Value Shares
Change 		Change in
Stake
O
101
OrbiMed
New York
$15.2K +$15.5M +1,041,300 New
PNC Financial Services Group
102
PNC Financial Services Group
Pennsylvania
$10K – – –
IA
103
IFP Advisors
Florida
$7K – – –
Macquarie Group
104
Macquarie Group
Australia
$6K -$1.34K -90 -21%
US Bancorp
105
US Bancorp
Minnesota
$5K -$4.72K -318 -47%
HPC
106
HM Payson & Co
Maine
$5K – – –
HCM
107
Highlander Capital Management
New Jersey
$5K +$1.99K +134 +58%
Baillie Gifford & Co
108
Baillie Gifford & Co
United Kingdom
$4K – – –
CCA
109
Column Capital Advisors
Indiana
$2K – – –
SPIA
110
Steward Partners Investment Advisory
New York
$2K – – –
Northwestern Mutual Wealth Management
111
Northwestern Mutual Wealth Management
Wisconsin
$1K -$89 -6 -9%
Russell Investments Group
112
Russell Investments Group
United Kingdom
$1K – – –
TC
113
Truvestments Capital
Florida
$1K – – –
WFA
114
Wipfli Financial Advisors
Wisconsin
$1K +$980 +66 New
LC
115
Lindbrook Capital
California
$1K +$1.38K +93 New
BC
116
Barrett & Company
Rhode Island
$618 +$980 +66 New
BCWM
117
Bartlett & Co Wealth Management
Ohio
$480 – – –
FFA
118
Fairfield Financial Advisors
Massachusetts
$291 – – –
APA
119
American Portfolios Advisors
New York
$247 – – –
LSA
120
Leonteq Securities AG
Switzerland
$15 – – –
6CM
121
683 Capital Management
New York
– -$2.77M -210,000 Closed
CH
122
CVI Holdings
Delaware
– -$1.7M -128,839 Closed
Qube Research & Technologies (QRT)
123
Qube Research & Technologies (QRT)
United Kingdom
– -$1.03M -77,759 Closed
CCM
124
Camber Capital Management
Massachusetts
– -$642K -48,600 Closed
QC
125
Quantedge Capital
Singapore
– -$197K -14,900 Closed
2 3 4
5
6

TSVT Hedge Fund Activity: Q3 2022 in Review

133 of the 5,805 institutional investors tracked by Wall St. Rank reported a position in 2seventy bio (TSVT) for Q3 2022, worth a combined $478M — up 9.7% from $436M a quarter earlier.

Buyers outnumbered sellers: 17 funds opened new TSVT positions and 16 closed out — a net gain of 1 holder — while 37 added to existing stakes and 36 trimmed.

The largest buyer was OrbiMed, opening a new position worth an estimated $15.5M. The largest seller was EcoR1 Capital, cutting an estimated $17.1M.

  • 133 institutional investors held 2seventy bio (TSVT) as of Q3 2022, up from 132 in Q2 2022.
  • Funds reported $478M of 2seventy bio stock for Q3 2022, up 9.7% quarter-over-quarter.
  • 17 funds opened new 2seventy bio positions in Q3 2022 and 16 closed out, a net change of +1 holder.
  • The largest 2seventy bio buyer in Q3 2022 was OrbiMed, an estimated $15.5M added.
  • The largest 2seventy bio seller in Q3 2022 was EcoR1 Capital, an estimated $17.1M sold.

Based on aggregated 13F filings for Q3 2022.