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TSVT

2seventy bio
TSVT

Delisted

TSVT was delisted on the 13th of May, 2025.

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133 hedge funds and large institutions have $544M invested in 2seventy bio in 2022 Q1 according to their latest regulatory filings, with 35 funds opening new positions, 35 increasing their positions, 31 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more funds holding in top 10

Funds holding in top 10: 1 → 3 (+2)

30% more first-time investments, than exits

New positions opened: 35 | Existing positions closed: 27

13% more capital invested

Capital invested by funds: $479M → $544M (+$64.6M)

13% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 31

5% more funds holding

Funds holding: 127 → 133 (+6)

Holders
133
Holders Change
+6
Holders Change %
+4.72%
% of All Funds
2.1%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.05%
New
35
Increased
35
Reduced
31
Closed
27
Calls
$395K
Puts
–
Net Calls
+$395K
Net Calls Change
-$226K

Top Buyers

Rank Fund Capital Flow
1
EC
EcoR1 Capital
California
+$26.8M
2
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
+$20.9M
3
BBA
Baker Bros. Advisors
New York
+$20.9M
4
RI
RTW Investments
New York
+$20.9M
5
AC
Armistice Capital
New York
+$19.4M

Top Sellers

Rank Fund Capital Flow
1
Vanguard Group
Vanguard Group
Pennsylvania
-$8.14M
2
Goldman Sachs
Goldman Sachs
New York
-$6.64M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
-$4.68M
4
PAMS
Pictet Asset Management (Switzerland)
Switzerland
-$1.99M
5
Principal Financial Group
Principal Financial Group
Iowa
-$1.98M
Name Holding Trade Value Shares
Change 		Change in
Stake
IA
101
IFP Advisors
Florida
$7K +$2.58K +152 New
HPC
102
HM Payson & Co
Maine
$6K – – –
Baillie Gifford & Co
103
Baillie Gifford & Co
United Kingdom
$5K – – –
DHGWA
104
Dixon Hughes Goodman Wealth Advisors
North Carolina
$5K +$5.09K +300 New
HCM
105
Highlander Capital Management
New Jersey
$4K – – –
DZ Bank
106
DZ Bank
Germany
$3.98K – – –
FFA
107
Freedman Financial Associates
Massachusetts
$3K – – –
Fidelity Investments
108
Fidelity Investments
Massachusetts
$3K +$3.14K +185 +6,167%
CCA
109
Column Capital Advisors
Indiana
$2K – – –
SPIA
110
Steward Partners Investment Advisory
New York
$2K – – –
M&T Bank
111
M&T Bank
New York
$2K +$1.83K +108 New
PFS
112
Prospera Financial Services
Texas
$2K +$2.39K +141 New
BFEC
113
Benjamin F. Edwards & Company
Missouri
$1K – – –
HWM
114
HighMark Wealth Management
Minnesota
$1K – – –
LWCFA
115
Loring Wolcott & Coolidge Fiduciary Advisors
Massachusetts
$1K – – –
Northwestern Mutual Wealth Management
116
Northwestern Mutual Wealth Management
Wisconsin
$1K – – –
PFBT
117
Parkside Financial Bank & Trust
Missouri
$1K – – –
IC
118
Ikarian Capital
Texas
$1K +$102 +6 +6%
BC
119
Bartlett & Co
Ohio
$1K +$560 +33 New
AIL
120
AGF Investments LLC
Ontario, Canada
$1K +$594 +35 New
BCWM
121
Bartlett & Co Wealth Management
Ohio
$563 +$560 +33 New
FFA
122
Fairfield Financial Advisors
Massachusetts
$341 +$339 +20 New
APA
123
American Portfolios Advisors
New York
$290 – – –
LSA
124
Leonteq Securities AG
Switzerland
$17 – – –
Macquarie Group
125
Macquarie Group
Australia
$7 – – –
2 3 4
5
6

TSVT Hedge Fund Activity: Q1 2022 in Review

133 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in 2seventy bio (TSVT) for Q1 2022, worth a combined $544M — up 13% from $479M a quarter earlier.

Buyers outnumbered sellers: 35 funds opened new TSVT positions and 27 closed out — a net gain of 8 holders — while 35 added to existing stakes and 31 trimmed.

The largest buyer was EcoR1 Capital, adding an estimated $26.8M. The largest seller was Vanguard Group, cutting an estimated $8.14M.

  • 133 institutional investors held 2seventy bio (TSVT) as of Q1 2022, up from 127 in Q4 2021.
  • Funds reported $544M of 2seventy bio stock for Q1 2022, up 13% quarter-over-quarter.
  • 35 funds opened new 2seventy bio positions in Q1 2022 and 27 closed out, a net change of +8 holders.
  • The largest 2seventy bio buyer in Q1 2022 was EcoR1 Capital, an estimated $26.8M added.
  • The largest 2seventy bio seller in Q1 2022 was Vanguard Group, an estimated $8.14M sold.

Based on aggregated 13F filings for Q1 2022.