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TSVT

2seventy bio
TSVT

Delisted

TSVT was delisted on the 13th of May, 2025.

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141 hedge funds and large institutions have $317M invested in 2seventy bio in 2022 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 40 increasing their positions, 32 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

148% more call options, than puts

Call options by funds: $500K | Put options by funds: $202K

58% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 19

25% more repeat investments, than reductions

Existing positions increased: 40 | Existing positions reduced: 32

6% more funds holding

Funds holding: 133 → 141 (+8)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

34% less capital invested

Capital invested by funds: $478M → $317M (-$161M)

Holders
141
Holders Change
+8
Holders Change %
+6.02%
% of All Funds
2.27%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
30
Increased
40
Reduced
32
Closed
19
Calls
$500K
Puts
$202K
Net Calls
+$298K
Net Calls Change
-$1.41M

Top Buyers

Rank Fund Capital Flow
1
CC
Casdin Capital
New York
+$17.4M
2
ECM
ExodusPoint Capital Management
New York
+$9.34M
3
Millennium Management
Millennium Management
New York
+$8.45M
4
BlackRock
BlackRock
New York
+$5.99M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$3.27M

Top Sellers

Rank Fund Capital Flow
1
AC
Armistice Capital
New York
-$18.4M
2
RI
RTW Investments
New York
-$17.9M
3
EC
EcoR1 Capital
California
-$16.9M
4
SC
Sessa Capital
New York
-$4.45M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
-$4.1M
Name Holding Trade Value Shares
Change 		Change in
Stake
FRM
76
Fox Run Management
Connecticut
$138K +$208K +14,754 New
State Board of Administration of Florida Retirement System
77
State Board of Administration of Florida Retirement System
Florida
$134K – – –
Legal & General Group
78
Legal & General Group
United Kingdom
$132K +$9.04K +641 +5%
SG Americas Securities
79
SG Americas Securities
New York
$127K +$26.5K +1,881 +16%
Mariner
80
Mariner
Kansas
$121K +$182K +12,914 New
GAA
81
Green Alpha Advisors
Colorado
$117K -$1.57K -111 -0.9%
AGM
82
Alpine Global Management
New York
$112K +$168K +11,930 New
TI
83
Trexquant Investment
Connecticut
$111K +$167K +11,872 New
Lazard Asset Management
84
Lazard Asset Management
New York
$110K +$43.2K +3,063 +35%
EGM
85
Engineers Gate Manager
New York
$110K +$165K +11,713 New
Principal Financial Group
86
Principal Financial Group
Iowa
$102K +$8.66K +614 +6%
Teacher Retirement System of Texas
87
Teacher Retirement System of Texas
Texas
$101K -$13.4K -949 -8%
GF
88
Gabelli Funds
New York
$97.8K -$16.5K -1,167 -10%
Walleye Trading
89
Walleye Trading
New York
$96.7K +$146K +10,323 New
AQR Capital Management
90
AQR Capital Management
Connecticut
$95.4K +$152K +10,811 New
ASRS
91
Arizona State Retirement System
Arizona
$95.1K +$143K +10,152 New
GCP
92
GSA Capital Partners
United Kingdom
$95K +$144K +10,186 New
OCBCO
93
Oversea-Chinese Banking Corp (OCBC)
Singapore
$94K +$141K +10,011 New
PMEF
94
Point72 Middle East FZE
United Arab Emirates
$82.8K +$125K +8,832 New
PCM
95
Penserra Capital Management
California
$77K -$109K -7,762 -48%
Royal Bank of Canada
96
Royal Bank of Canada
Ontario, Canada
$58K +$24.4K +1,729 +39%
DA
97
Denali Advisors
California
$56.2K +$84.6K +6,000 New
EAM
98
Erste Asset Management
Austria
$44.8K – – –
Simplex Trading
99
Simplex Trading
Illinois
$44K -$16K -1,136 -19%
AB
100
Amalgamated Bank
New York
$44K – – –
2 3
4
5 6

TSVT Hedge Fund Activity: Q4 2022 in Review

141 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in 2seventy bio (TSVT) for Q4 2022, worth a combined $317M — down 34% from $478M a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new TSVT positions and 19 closed out — a net gain of 11 holders — while 40 added to existing stakes and 32 trimmed.

The largest buyer was Casdin Capital, adding an estimated $17.4M. The largest seller was Armistice Capital, exiting entirely with an estimated $18.4M sold.

  • 141 institutional investors held 2seventy bio (TSVT) as of Q4 2022, up from 133 in Q3 2022.
  • Funds reported $317M of 2seventy bio stock for Q4 2022, down 34% quarter-over-quarter.
  • 30 funds opened new 2seventy bio positions in Q4 2022 and 19 closed out, a net change of +11 holders.
  • The largest 2seventy bio buyer in Q4 2022 was Casdin Capital, an estimated $17.4M added.
  • The largest 2seventy bio seller in Q4 2022 was Armistice Capital, an estimated $18.4M sold.

Based on aggregated 13F filings for Q4 2022.