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TSVT

2seventy bio
TSVT

Delisted

TSVT was delisted on the 13th of May, 2025.

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141 hedge funds and large institutions have $317M invested in 2seventy bio in 2022 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 40 increasing their positions, 32 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

148% more call options, than puts

Call options by funds: $500K | Put options by funds: $202K

58% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 19

25% more repeat investments, than reductions

Existing positions increased: 40 | Existing positions reduced: 32

6% more funds holding

Funds holding: 133 → 141 (+8)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

34% less capital invested

Capital invested by funds: $478M → $317M (-$161M)

Holders
141
Holders Change
+8
Holders Change %
+6.02%
% of All Funds
2.27%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
30
Increased
40
Reduced
32
Closed
19
Calls
$500K
Puts
$202K
Net Calls
+$298K
Net Calls Change
-$1.41M

Top Buyers

Rank Fund Capital Flow
1
CC
Casdin Capital
New York
+$17.4M
2
ECM
ExodusPoint Capital Management
New York
+$9.34M
3
Millennium Management
Millennium Management
New York
+$8.45M
4
BlackRock
BlackRock
New York
+$5.99M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$3.27M

Top Sellers

Rank Fund Capital Flow
1
AC
Armistice Capital
New York
-$18.4M
2
RI
RTW Investments
New York
-$17.9M
3
EC
EcoR1 Capital
California
-$16.9M
4
SC
Sessa Capital
New York
-$4.45M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
-$4.1M
Name Holding Trade Value Shares
Change 		Change in
Stake
HWAM
51
Hennion & Walsh Asset Management
New Jersey
$322K +$48.3K +3,427 +11%
State of Wisconsin Investment Board
52
State of Wisconsin Investment Board
Wisconsin
$313K -$30.7K -2,174 -6%
Russell Investments Group
53
Russell Investments Group
United Kingdom
$304K +$456K +32,324 +34,757%
Invesco
54
Invesco
Georgia
$302K +$8.93K +633 +2%
LNWWM
55
Laird Norton Wetherby Wealth Management
California
$288K +$196K +13,893 +82%
Walleye Capital
56
Walleye Capital
New York
$287K +$206K +14,576 +91%
VOYA Investment Management
57
VOYA Investment Management
Georgia
$280K +$209K +14,818 +99%
Los Angeles Capital Management
58
Los Angeles Capital Management
California
$255K – – –
New York State Common Retirement Fund
59
New York State Common Retirement Fund
New York
$248K +$14 +1 +0%
VEA
60
Virtus ETF Advisers
New York
$230K +$347K +24,598 New
JF
61
Jump Financial
Illinois
$222K +$335K +23,725 New
CG
62
Colony Group
Massachusetts
$218K +$126K +8,968 +63%
KHCM
63
Kettle Hill Capital Management
New York
$215K +$9.87K +700 +3%
Jane Street
64
Jane Street
New York
$214K +$323K +22,864 New
PI
65
Putnam Investments
Massachusetts
$207K -$65.9K -4,673 -17%
MIM
66
MetLife Investment Management
New Jersey
$194K – – –
Susquehanna International Group
67
Susquehanna International Group
Pennsylvania
$190K -$371K -26,327 -56%
Renaissance Technologies
68
Renaissance Technologies
New York
$181K +$272K +19,300 New
ACM
69
Aquatic Capital Management
Illinois
$176K +$265K +18,800 New
Deutsche Bank
70
Deutsche Bank
Germany
$174K -$658K -46,618 -72%
AIG
71
American International Group
New York
$166K -$903 -64 -0.4%
T. Rowe Price Associates
72
T. Rowe Price Associates
Maryland
$151K +$8.41K +596 +4%
Mitsubishi UFJ Asset Management
73
Mitsubishi UFJ Asset Management
Japan
$149K +$226K +16,029 New
Manulife (Manufacturers Life Insurance)
74
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$142K +$3.91K +277 +2%
FT
75
Fiduciary Trust
Massachusetts
$142K +$28.8K +2,043 +16%
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3
4 5

TSVT Hedge Fund Activity: Q4 2022 in Review

141 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in 2seventy bio (TSVT) for Q4 2022, worth a combined $317M — down 34% from $478M a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new TSVT positions and 19 closed out — a net gain of 11 holders — while 40 added to existing stakes and 32 trimmed.

The largest buyer was Casdin Capital, adding an estimated $17.4M. The largest seller was Armistice Capital, exiting entirely with an estimated $18.4M sold.

  • 141 institutional investors held 2seventy bio (TSVT) as of Q4 2022, up from 133 in Q3 2022.
  • Funds reported $317M of 2seventy bio stock for Q4 2022, down 34% quarter-over-quarter.
  • 30 funds opened new 2seventy bio positions in Q4 2022 and 19 closed out, a net change of +11 holders.
  • The largest 2seventy bio buyer in Q4 2022 was Casdin Capital, an estimated $17.4M added.
  • The largest 2seventy bio seller in Q4 2022 was Armistice Capital, an estimated $18.4M sold.

Based on aggregated 13F filings for Q4 2022.