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TSVT

2seventy bio
TSVT

Delisted

TSVT was delisted on the 13th of May, 2025.

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145 hedge funds and large institutions have $215M invested in 2seventy bio in 2023 Q3 according to their latest regulatory filings, with 25 funds opening new positions, 52 increasing their positions, 28 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed

86% more repeat investments, than reductions

Existing positions increased: 52 | Existing positions reduced: 28

3% less funds holding

Funds holding: 149 → 145 (-4)

14% less first-time investments, than exits

New positions opened: 25 | Existing positions closed: 29

48% less call options, than puts

Call options by funds: $50K | Put options by funds: $96K

50% less funds holding in top 10

Funds holding in top 10: 2 → 1 (-1)

57% less capital invested

Capital invested by funds: $505M → $215M (-$290M)

Holders
145
Holders Change
-4
Holders Change %
-2.68%
% of All Funds
2.3%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.02%
New
25
Increased
52
Reduced
28
Closed
29
Calls
$50K
Puts
$96K
Net Calls
-$46K
Net Calls Change
-$794K

Top Buyers

Rank Fund Capital Flow
1
NM
Newtyn Management
New York
+$15.3M
2
MAP
Madison Avenue Partners
New York
+$9.8M
3
EP
Eversept Partners
New York
+$9.53M
4
KCM
Kynam Capital Management
New Jersey
+$6.97M
5
DCM
DAFNA Capital Management
California
+$6.24M

Top Sellers

Rank Fund Capital Flow
1
O
OrbiMed
New York
-$24.2M
2
APM
Avidity Partners Management
Texas
-$13.6M
3
State Street
State Street
Massachusetts
-$13.1M
4
Goldman Sachs
Goldman Sachs
New York
-$5.82M
5
SAM
Sectoral Asset Management
Quebec, Canada
-$4.68M
Name Holding Trade Value Shares
Change 		Change in
Stake
CCP
26
Clough Capital Partners
Massachusetts
$2M -$119K -18,200 -3%
BC
27
Boxer Capital
California
$1.8M – – –
Northern Trust
28
Northern Trust
Illinois
$1.77M -$46.4K -7,076 -2%
Citadel Advisors
29
Citadel Advisors
Florida
$1.5M +$1.17M +178,117 +87%
ECM
30
Engine Capital Management
New York
$1.34M +$2.24M +341,870 New
Bank of America
31
Bank of America
North Carolina
$1.2M +$1.02M +155,647 +104%
Fidelity Investments
32
Fidelity Investments
Massachusetts
$1.13M -$199K -30,373 -10%
AQR Capital Management
33
AQR Capital Management
Connecticut
$1.13M +$1.86M +284,124 +1,931%
Dimensional Fund Advisors
34
Dimensional Fund Advisors
Texas
$1.1M -$198K -30,200 -10%
Mirae Asset Global Investments
35
Mirae Asset Global Investments
South Korea
$972K +$173K +26,384 +12%
PAM
36
Panagora Asset Management
Massachusetts
$852K +$1.42M +217,230 New
Bank of New York Mellon
37
Bank of New York Mellon
New York
$711K -$19K -2,893 -2%
Jane Street
38
Jane Street
New York
$561K +$603K +91,897 +179%
Susquehanna International Group
39
Susquehanna International Group
Pennsylvania
$559K +$349K +53,178 +60%
Prudential Financial
40
Prudential Financial
New Jersey
$471K +$132K +20,100 +20%
MCM
41
Moore Capital Management
New York
$464K -$536K -81,687 -41%
Ameriprise
42
Ameriprise
Minnesota
$448K +$267K +40,688 +55%
Renaissance Technologies
43
Renaissance Technologies
New York
$387K +$648K +98,839 New
Swiss National Bank
44
Swiss National Bank
Switzerland
$385K – – –
N
45
Nuveen
North Carolina
$379K -$8.36K -1,275 -1%
HSBC Holdings
46
HSBC Holdings
United Kingdom
$339K +$576K +87,828 New
Ohio Public Employees Retirement System (OPERS)
47
Ohio Public Employees Retirement System (OPERS)
Ohio
$332K +$294K +44,895 +113%
RhumbLine Advisers
48
RhumbLine Advisers
Massachusetts
$315K +$2.62K +399 +0.5%
GCM
49
Graham Capital Management
Connecticut
$297K +$329K +50,166 +195%
TI
50
Trexquant Investment
Connecticut
$287K +$145K +22,172 +43%
1
2
3 4 5

TSVT Hedge Fund Activity: Q3 2023 in Review

145 of the 6,301 institutional investors tracked by Wall St. Rank reported a position in 2seventy bio (TSVT) for Q3 2023, worth a combined $215M — down 57% from $505M a quarter earlier.

Sellers outnumbered buyers: 29 funds closed out of TSVT and 25 opened new positions — a net loss of 4 holders — while 28 trimmed existing stakes and 52 added.

The largest buyer was Newtyn Management, adding an estimated $15.3M. The largest seller was OrbiMed, exiting entirely with an estimated $24.2M sold.

  • 145 institutional investors held 2seventy bio (TSVT) as of Q3 2023, down from 149 in Q2 2023.
  • Funds reported $215M of 2seventy bio stock for Q3 2023, down 57% quarter-over-quarter.
  • 25 funds opened new 2seventy bio positions in Q3 2023 and 29 closed out, a net change of -4 holders.
  • The largest 2seventy bio buyer in Q3 2023 was Newtyn Management, an estimated $15.3M added.
  • The largest 2seventy bio seller in Q3 2023 was OrbiMed, an estimated $24.2M sold.

Based on aggregated 13F filings for Q3 2023.