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TSVT

2seventy bio
TSVT

Delisted

TSVT was delisted on the 13th of May, 2025.

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141 hedge funds and large institutions have $317M invested in 2seventy bio in 2022 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 40 increasing their positions, 32 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

148% more call options, than puts

Call options by funds: $500K | Put options by funds: $202K

58% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 19

25% more repeat investments, than reductions

Existing positions increased: 40 | Existing positions reduced: 32

6% more funds holding

Funds holding: 133 → 141 (+8)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

34% less capital invested

Capital invested by funds: $478M → $317M (-$161M)

Holders
141
Holders Change
+8
Holders Change %
+6.02%
% of All Funds
2.27%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
30
Increased
40
Reduced
32
Closed
19
Calls
$500K
Puts
$202K
Net Calls
+$298K
Net Calls Change
-$1.41M

Top Buyers

Rank Fund Capital Flow
1
CC
Casdin Capital
New York
+$17.4M
2
ECM
ExodusPoint Capital Management
New York
+$9.34M
3
Millennium Management
Millennium Management
New York
+$8.45M
4
BlackRock
BlackRock
New York
+$5.99M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$3.27M

Top Sellers

Rank Fund Capital Flow
1
AC
Armistice Capital
New York
-$18.4M
2
RI
RTW Investments
New York
-$17.9M
3
EC
EcoR1 Capital
California
-$16.9M
4
SC
Sessa Capital
New York
-$4.45M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
-$4.1M
Name Holding Trade Value Shares
Change 		Change in
Stake
Citadel Advisors
26
Citadel Advisors
Florida
$2.45M +$2.06M +146,054 +126%
PVI
27
Pura Vida Investments
New York
$2.35M -$1.04M -73,691 -23%
TCM
28
Tang Capital Management
California
$2.34M -$705K -50,000 -17%
Morgan Stanley
29
Morgan Stanley
New York
$2M +$2.18M +154,808 +266%
AA
30
AlphaCentric Advisors
Puerto Rico
$1.69M +$1.59M +113,000 +169%
WAM
31
Weiss Asset Management
Massachusetts
$1.52M – – –
Bank of America
32
Bank of America
North Carolina
$1.42M +$406K +28,784 +23%
Mirae Asset Global Investments
33
Mirae Asset Global Investments
South Korea
$1.38M -$609K -43,141 -23%
Bank of New York Mellon
34
Bank of New York Mellon
New York
$1.26M -$36.8K -2,612 -2%
Rafferty Asset Management
35
Rafferty Asset Management
New York
$1.23M +$29.3K +2,078 +2%
Jacobs Levy Equity Management
36
Jacobs Levy Equity Management
New Jersey
$1.08M +$170K +12,047 +12%
UBS Group
37
UBS Group
Switzerland
$870K +$1.06M +74,961 +419%
N
38
Nuveen
North Carolina
$869K -$250K -17,709 -16%
Swiss National Bank
39
Swiss National Bank
Switzerland
$813K +$40.9K +2,900 +3%
Man Group
40
Man Group
United Kingdom
$745K +$1.12M +79,504 New
Barclays
41
Barclays
United Kingdom
$722K -$89.3K -6,332 -8%
SFI
42
Susquehanna Fundamental Investments
Pennsylvania
$632K +$952K +67,493 New
Citigroup
43
Citigroup
New York
$605K -$777K -55,091 -46%
BC
44
Birchview Capital
Vermont
$561K – – –
RhumbLine Advisers
45
RhumbLine Advisers
Massachusetts
$545K +$8.63K +612 +1%
Qube Research & Technologies (QRT)
46
Qube Research & Technologies (QRT)
United Kingdom
$477K +$718K +50,878 New
UBS AM
47
UBS AM
Illinois
$443K – – –
California State Teachers Retirement System (CalSTRS)
48
California State Teachers Retirement System (CalSTRS)
California
$433K +$9.44K +669 +1%
AllianceBernstein
49
AllianceBernstein
Tennessee
$332K – – –
Ohio Public Employees Retirement System (OPERS)
50
Ohio Public Employees Retirement System (OPERS)
Ohio
$332K -$113K -8,038 -18%
1
2
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TSVT Hedge Fund Activity: Q4 2022 in Review

141 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in 2seventy bio (TSVT) for Q4 2022, worth a combined $317M — down 34% from $478M a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new TSVT positions and 19 closed out — a net gain of 11 holders — while 40 added to existing stakes and 32 trimmed.

The largest buyer was Casdin Capital, adding an estimated $17.4M. The largest seller was Armistice Capital, exiting entirely with an estimated $18.4M sold.

  • 141 institutional investors held 2seventy bio (TSVT) as of Q4 2022, up from 133 in Q3 2022.
  • Funds reported $317M of 2seventy bio stock for Q4 2022, down 34% quarter-over-quarter.
  • 30 funds opened new 2seventy bio positions in Q4 2022 and 19 closed out, a net change of +11 holders.
  • The largest 2seventy bio buyer in Q4 2022 was Casdin Capital, an estimated $17.4M added.
  • The largest 2seventy bio seller in Q4 2022 was Armistice Capital, an estimated $18.4M sold.

Based on aggregated 13F filings for Q4 2022.