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TSVT

2seventy bio
TSVT

Delisted

TSVT was delisted on the 13th of May, 2025.

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133 hedge funds and large institutions have $544M invested in 2seventy bio in 2022 Q1 according to their latest regulatory filings, with 35 funds opening new positions, 35 increasing their positions, 31 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more funds holding in top 10

Funds holding in top 10: 1 → 3 (+2)

30% more first-time investments, than exits

New positions opened: 35 | Existing positions closed: 27

13% more capital invested

Capital invested by funds: $479M → $544M (+$64.6M)

13% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 31

5% more funds holding

Funds holding: 127 → 133 (+6)

Holders
133
Holders Change
+6
Holders Change %
+4.72%
% of All Funds
2.1%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.05%
New
35
Increased
35
Reduced
31
Closed
27
Calls
$395K
Puts
–
Net Calls
+$395K
Net Calls Change
-$226K

Top Buyers

Rank Fund Capital Flow
1
EC
EcoR1 Capital
California
+$26.8M
2
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
+$20.9M
3
BBA
Baker Bros. Advisors
New York
+$20.9M
4
RI
RTW Investments
New York
+$20.9M
5
AC
Armistice Capital
New York
+$19.4M

Top Sellers

Rank Fund Capital Flow
1
Vanguard Group
Vanguard Group
Pennsylvania
-$8.14M
2
Goldman Sachs
Goldman Sachs
New York
-$6.64M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
-$4.68M
4
PAMS
Pictet Asset Management (Switzerland)
Switzerland
-$1.99M
5
Principal Financial Group
Principal Financial Group
Iowa
-$1.98M
Name Holding Trade Value Shares
Change 		Change in
Stake
TCM
26
Tang Capital Management
California
$5.12M +$5.09M +300,000 New
ECM
27
ExodusPoint Capital Management
New York
$3.98M +$1.78M +104,699 +81%
Northern Trust
28
Northern Trust
Illinois
$3.78M -$26K -1,532 -0.7%
Rafferty Asset Management
29
Rafferty Asset Management
New York
$3.75M +$664K +39,121 +22%
Charles Schwab
30
Charles Schwab
California
$2.9M +$104K +6,143 +4%
UBS Group
31
UBS Group
Switzerland
$2.6M +$1.57M +92,364 +154%
CCM
32
CAAS Capital Management
New York
$2.49M -$953K -56,153 -28%
Norges Bank
33
Norges Bank
Norway
$2.45M +$425K +25,057 +21%
Dimensional Fund Advisors
34
Dimensional Fund Advisors
Texas
$2.02M -$47.1K -2,779 -2%
Goldman Sachs
35
Goldman Sachs
New York
$2M -$6.64M -391,237 -77%
ACM
36
Altium Capital Management
New York
$1.96M +$1.95M +115,000 New
Bank of New York Mellon
37
Bank of New York Mellon
New York
$1.49M -$38.9K -2,291 -3%
Swiss National Bank
38
Swiss National Bank
Switzerland
$1.43M +$580K +34,200 +69%
N
39
Nuveen
North Carolina
$1.39M +$15.2K +895 +1%
Susquehanna International Group
40
Susquehanna International Group
Pennsylvania
$1.27M -$313K -18,465 -20%
LP
41
LMR Partners
United Kingdom
$1.26M +$318K +18,772 +34%
Mirae Asset Global Investments
42
Mirae Asset Global Investments
South Korea
$1.21M -$263K -15,515 -18%
Jane Street
43
Jane Street
New York
$1.07M +$434K +25,606 +69%
Swedbank
44
Swedbank
Sweden
$768K – – –
NFGH
45
Nan Fung Group Holdings
Hong Kong
$687K +$683K +40,273 New
California State Teachers Retirement System (CalSTRS)
46
California State Teachers Retirement System (CalSTRS)
California
$685K +$152K +8,939 +29%
CRC
47
Curi RMB Capital
Illinois
$649K – – –
Citigroup
48
Citigroup
New York
$639K -$1.79M -105,295 -74%
QC
49
Quantedge Capital
Singapore
$611K +$607K +35,800 New
BC
50
Birchview Capital
Vermont
$586K +$107K +6,334 +23%
1
2
3 4 5

TSVT Hedge Fund Activity: Q1 2022 in Review

133 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in 2seventy bio (TSVT) for Q1 2022, worth a combined $544M — up 13% from $479M a quarter earlier.

Buyers outnumbered sellers: 35 funds opened new TSVT positions and 27 closed out — a net gain of 8 holders — while 35 added to existing stakes and 31 trimmed.

The largest buyer was EcoR1 Capital, adding an estimated $26.8M. The largest seller was Vanguard Group, cutting an estimated $8.14M.

  • 133 institutional investors held 2seventy bio (TSVT) as of Q1 2022, up from 127 in Q4 2021.
  • Funds reported $544M of 2seventy bio stock for Q1 2022, up 13% quarter-over-quarter.
  • 35 funds opened new 2seventy bio positions in Q1 2022 and 27 closed out, a net change of +8 holders.
  • The largest 2seventy bio buyer in Q1 2022 was EcoR1 Capital, an estimated $26.8M added.
  • The largest 2seventy bio seller in Q1 2022 was Vanguard Group, an estimated $8.14M sold.

Based on aggregated 13F filings for Q1 2022.