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TriSalus Life Sciences
TLSI

67 hedge funds and large institutions have $79.8M invested in TriSalus Life Sciences in 2025 Q4 according to their latest regulatory filings, with 15 funds opening new positions, 26 increasing their positions, 13 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more repeat investments, than reductions

Existing positions increased: 26 | Existing positions reduced: 13

88% more first-time investments, than exits

New positions opened: 15 | Existing positions closed: 8

79% more capital invested

Capital invested by funds: $44.6M → $79.8M (+$35.2M)

12% more funds holding

Funds holding: 60 → 67 (+7)

3.65% more ownership

Funds ownership: 19.22% → 22.88% (+3.7%)

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

Holders
67
Holders Change
+7
Holders Change %
+11.67%
% of All Funds
0.81%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
15
Increased
26
Reduced
13
Closed
8
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
+$4.18M
2
Vanguard Group
Vanguard Group
Pennsylvania
+$2.08M
3
Morgan Stanley
Morgan Stanley
New York
+$1.94M
4
Geode Capital Management
Geode Capital Management
Massachusetts
+$1.1M
5
EFMC
Empire Financial Management Company
New York
+$403K

Top Sellers

Rank Fund Capital Flow
1
Alyeska Investment Group
Alyeska Investment Group
Illinois
-$840K
2
Goldman Sachs
Goldman Sachs
New York
-$473K
3
GGHC
Gilder Gagnon Howe & Co
New York
-$381K
4
Corient Private Wealth
Corient Private Wealth
Florida
-$352K
5
Squarepoint
Squarepoint
New York
-$164K
Name Holding Trade Value Shares
Change 		Change in
Stake
TRCT
51
Tower Research Capital (TRC)
New York
$12.4K -$6.94K -1,240 -41%
AIP
52
Ameritas Investment Partners
Nebraska
$11.4K – – –
SCM
53
Sterling Capital Management
North Carolina
$9.57K +$2.09K +373 +37%
Royal Bank of Canada
54
Royal Bank of Canada
Ontario, Canada
$8K +$4.72K +843 +240%
AB
55
Amalgamated Bank
New York
$7K +$2.3K +411 +75%
Citigroup
56
Citigroup
New York
$4.8K +$1.84K +329 +92%
HRC
57
Hoertkorn Richard Charles
$4.66K – – –
JFG
58
JDM Financial Group
Texas
$3.7K – – –
RDFA
59
Ritter Daniher Financial Advisory
Ohio
$3.49K +$2.8K +500 New
Carson Wealth (CWM LLC)
60
Carson Wealth (CWM LLC)
Nebraska
$1K -$67 -12 -13%
S
61
SignatureFD
Georgia
$698 – – –
GI
62
GAMMA Investing
California
$405 +$325 +58 New
RIAS
63
Rachor Investment Advisory Services
Michigan
$356 +$286 +51 New
PNC Financial Services Group
64
PNC Financial Services Group
Pennsylvania
$154 -$241 -43 -66%
EP
65
Essential Partners
California
$154 – – –
RIL
66
Rothschild Investment LLC
Illinois
$7 +$6 +1 New
TWD
67
True Wealth Design
Ohio
$7 +$6 +1 New
Corient Private Wealth
68
Corient Private Wealth
Florida
– -$352K -75,700 Closed
VI
69
Vestcor Inc
New Brunswick, Canada
– -$109K -23,376 Closed
SFA
70
Sequoia Financial Advisors
Ohio
– -$90.5K -19,456 Closed
WAM
71
Wolverine Asset Management
Illinois
– -$3.81K -820 Closed
EWA
72
EverSource Wealth Advisors
Alabama
– -$446 -96 Closed
ASN
73
Advisory Services Network
Georgia
– -$33 -7 Closed
SS
74
SBI Securities
Japan
– -$9 -2 Closed
IA
75
IFP Advisors
Florida
– -$5 -1 Closed
1 2
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TLSI Hedge Fund Activity: Q4 2025 in Review

67 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in TriSalus Life Sciences (TLSI) for Q4 2025, worth a combined $79.8M — up 79% from $44.6M a quarter earlier.

Buyers outnumbered sellers: 15 funds opened new TLSI positions and 8 closed out — a net gain of 7 holders — while 26 added to existing stakes and 13 trimmed.

The largest buyer was BlackRock, adding an estimated $4.18M. The largest seller was Alyeska Investment Group, cutting an estimated $840K.

  • 67 institutional investors held TriSalus Life Sciences (TLSI) as of Q4 2025, up from 60 in Q3 2025.
  • Funds reported $79.8M of TriSalus Life Sciences stock for Q4 2025, up 79% quarter-over-quarter.
  • 15 funds opened new TriSalus Life Sciences positions in Q4 2025 and 8 closed out, a net change of +7 holders.
  • The largest TriSalus Life Sciences buyer in Q4 2025 was BlackRock, an estimated $4.18M added.
  • The largest TriSalus Life Sciences seller in Q4 2025 was Alyeska Investment Group, an estimated $840K sold.

Based on aggregated 13F filings for Q4 2025.