Tiziana Life Sciences
TLSA
33 hedge funds and large institutions have $3.06M invested in Tiziana Life Sciences in 2025 Q4 according to their latest regulatory filings, with 7 funds opening new positions, 7 increasing their positions, 6 reducing their positions, and 5 closing their positions.
2,775% more call options, than puts
Call options by funds: $115K | Put options by funds: $4K
40% more first-time investments, than exits
New positions opened: 7 | Existing positions closed: 5
17% more repeat investments, than reductions
Existing positions increased: 7 | Existing positions reduced: 6
6% more funds holding
Funds holding: 31 → 33 (+2)
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
0.92% less ownership
Funds ownership: 3.46% → 2.54% (-0.92%)
65% less capital invested
Capital invested by funds: $8.72M → $3.06M (-$5.65M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Goldman Sachs
New York
|
+$160K |
| 2 |
UBS Group
Zurich,
Switzerland
|
+$147K |
| 3 |
Focus Partners Wealth
Boston,
Massachusetts
|
+$144K |
| 4 |
OAC
OMERS Administration Corp
Toronto,
Ontario, Canada
|
+$71.1K |
| 5 |
HF
HRT Financial
New York
|
+$44K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
DIG
Dauntless Investment Group
Etna,
New Hampshire
|
-$1.75M |
| 2 |
Millennium Management
New York
|
-$340K |
| 3 |
Kovitz Investment Group Partners
Chicago,
Illinois
|
-$171K |
| 4 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
-$87K |
| 5 |
QC
Quadrature Capital
London,
United Kingdom
|
-$80.8K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
26
US Bancorp
Minneapolis,
Minnesota
| $1.49K | -$16.4K | -9,157 | -90% |
|
|
MCA
27
McGuire Capital Advisors
Bethany,
Oklahoma
| $1.29K | +$1.56K | +867 | New |
|
28
Carson Wealth (CWM LLC)
Omaha,
Nebraska
| $1K | +$898 | +500 | New |
|
29
Jones Financial Companies
Des Peres,
Missouri
| $969 | – | – | – |
|
30
Bank of America
Charlotte,
North Carolina
| $772 | – | – | – |
|
|
BWM
31
Bernard Wealth Management
Royal Oak,
Michigan
| $745 | – | – | – |
|
|
TCM
32
Tradewinds Capital Management
Bellingham,
Washington
| $385 | – | – | – |
|
|
SPIA
33
Steward Partners Investment Advisory
New York
| $365 | +$440 | +245 | New |
|
|
34
Kovitz Investment Group Partners
Chicago,
Illinois
| – | -$171K | -79,365 | Closed |
|
|
QC
35
Quadrature Capital
London,
United Kingdom
| – | -$80.8K | -37,405 | Closed |
|
|
AIP
36
ARS Investment Partners
New York
| – | -$66.3K | -30,700 | Closed |
|
37
Jane Street
New York
| – | -$38.9K | -17,987 | Closed |
|
|
CJ
38
Caitlin John
Brighton,
Michigan
| – | -$7.56K | -3,500 | Closed |
|
TLSA Hedge Fund Activity: Q4 2025 in Review
33 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Tiziana Life Sciences (TLSA) for Q4 2025, worth a combined $3.06M — down 65% from $8.72M a quarter earlier.
Buyers outnumbered sellers: 7 funds opened new TLSA positions and 5 closed out — a net gain of 2 holders — while 7 added to existing stakes and 6 trimmed.
The largest buyer was Goldman Sachs, adding an estimated $160K. The largest seller was Dauntless Investment Group, cutting an estimated $1.75M.
- 33 institutional investors held Tiziana Life Sciences (TLSA) as of Q4 2025, up from 31 in Q3 2025.
- Funds reported $3.06M of Tiziana Life Sciences stock for Q4 2025, down 65% quarter-over-quarter.
- 7 funds opened new Tiziana Life Sciences positions in Q4 2025 and 5 closed out, a net change of +2 holders.
- The largest Tiziana Life Sciences buyer in Q4 2025 was Goldman Sachs, an estimated $160K added.
- The largest Tiziana Life Sciences seller in Q4 2025 was Dauntless Investment Group, an estimated $1.75M sold.
Based on aggregated 13F filings for Q4 2025.