Sage TherapeuticsSAGE
About: Sage Therapeutics Inc is a clinical-stage biopharmaceutical company focused on brain health medicines. The company is targeting diseases and disorders of the brain with three key focus areas: depression, neurology and neuropsychiatry; also targeting two critical central nervous system, or CNS, receptor systems, GABA and NMDA. Its products ZURZUVAE is a medicine for the treatment of postpartum depression, or PPD, in adults, and ZULRESSO is a CIV injection for the treatment of postpartum depression in individuals 15 years old and older. It also has other drugs in its pipeline such as SAGE-324, Dalzanemdor (SAGE-718) among others.
Employees: 487
Fund manager confidence
Based on 2025 Q1 regulatory disclosures by fund managers ($100M+ AUM)
100% more funds holding in top 10
Funds holding in top 10: 1 [Q4 2024] → 2 (+1) [Q1 2025]
62% more first-time investments, than exits
New positions opened: 60 | Existing positions closed: 37
48% more capital invested
Capital invested by funds: $278M [Q4 2024] → $411M (+$133M) [Q1 2025]
13% more funds holding
Funds holding: 176 [Q4 2024] → 198 (+22) [Q1 2025]
0.44% more ownership
Funds ownership: 83.74% [Q4 2024] → 84.18% (+0.44%) [Q1 2025]
6% less repeat investments, than reductions
Existing positions increased: 50 | Existing positions reduced: 53
20% less call options, than puts
Call options by funds: $2.1M | Put options by funds: $2.63M
Research analyst outlook
We haven’t received any recent analyst ratings for SAGE.
Financial journalist opinion
Based on 15 articles about SAGE published over the past 30 days









