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Regeneron Pharmaceuticals

1,291 hedge funds and large institutions have $59.1B invested in Regeneron Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 139 funds opening new positions, 528 increasing their positions, 453 reducing their positions, and 147 closing their positions.

New
Increased
Maintained
Reduced
Closed

17% more repeat investments, than reductions

Existing positions increased: 528 | Existing positions reduced: 453

7% more funds holding in top 10

Funds holding in top 10: 1415 (+1)

0.26% more ownership

Funds ownership: 86.53%86.78% (+0.26%)

3% less call options, than puts

Call options by funds: $974M | Put options by funds: $1B

5% less first-time investments, than exits

New positions opened: 139 | Existing positions closed: 147

2% less funds holding

Funds holding: 1,3181,291 (-27)

11% less capital invested

Capital invested by funds: $66.7B → $59.1B (-$7.51B)

Holders
1,291
Holders Change
-27
Holders Change %
-2.05%
% of All Funds
17.31%
Holding in Top 10
15
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+7.14%
% of All Funds
0.2%
New
139
Increased
528
Reduced
453
Closed
147
Calls
$974M
Puts
$1B
Net Calls
-$27.6M
Net Calls Change
-$47.5M
Name Holding Trade Value Shares
Change
Change in
Stake
Bank of New York Mellon
26
Bank of New York Mellon
New York
$443M +$6.18M +8,990 +1%
AllianceBernstein
27
AllianceBernstein
Tennessee
$387M -$9.32M -13,548 -2%
D.E. Shaw & Co
28
D.E. Shaw & Co
New York
$367M +$54.1M +78,659 +16%
Dimensional Fund Advisors
29
Dimensional Fund Advisors
Texas
$362M -$10.9M -15,838 -3%
Two Sigma Advisers
30
Two Sigma Advisers
New York
$351M +$381M +553,800 New
Deutsche Bank
31
Deutsche Bank
Germany
$344M +$2.63M +3,823 +0.7%
N
32
Nuveen
North Carolina
$344M +$45.7M +66,388 +14%
BNP Paribas Asset Management
33
BNP Paribas Asset Management
France
$338M +$14.2M +20,658 +4%
Assenagon Asset Management
34
Assenagon Asset Management
Luxembourg
$305M +$209M +303,785 +171%
California Public Employees Retirement System
35
California Public Employees Retirement System
California
$300M +$75.6M +109,954 +30%
Neuberger Berman Group
36
Neuberger Berman Group
New York
$277M -$17.9M -26,021 -6%
Pacer Advisors
37
Pacer Advisors
Pennsylvania
$258M +$269M +390,374 +2,297%
Manulife (Manufacturers Life Insurance)
38
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$253M +$28.8M +41,826 +12%
HSBC Holdings
39
HSBC Holdings
United Kingdom
$247M -$30.4M -44,206 -10%
Two Sigma Investments
40
Two Sigma Investments
New York
$236M +$232M +337,528 +977%
TD Asset Management
41
TD Asset Management
Ontario, Canada
$223M -$5.16M -7,502 -2%
Ameriprise
42
Ameriprise
Minnesota
$216M +$9.35M +13,594 +4%
Barclays
43
Barclays
United Kingdom
$204M -$43.9M -63,821 -17%
Swiss National Bank
44
Swiss National Bank
Switzerland
$193M -$1.03M -1,500 -0.5%
Sumitomo Mitsui Trust Group
45
Sumitomo Mitsui Trust Group
Japan
$193M +$724K +1,053 +0.3%
Pictet Asset Management
46
Pictet Asset Management
Switzerland
$191M +$59.7M +86,859 +41%
UBS Group
47
UBS Group
Switzerland
$182M -$65.8M -95,672 -25%
Squarepoint
48
Squarepoint
New York
$180M +$20.2M +29,424 +12%
National Pension Service
49
National Pension Service
South Korea
$160M +$14.2M +20,596 +9%
Aberdeen Group
50
Aberdeen Group
United Kingdom
$156M +$39M +56,746 +30%

REGN Hedge Fund Activity: Q1 2025 in Review

1,291 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Regeneron Pharmaceuticals (REGN) for Q1 2025, worth a combined $59.1B — down 11% from $66.7B a quarter earlier.

Sellers outnumbered buyers: 147 funds closed out of REGN and 139 opened new positions — a net loss of 8 holders — while 453 trimmed existing stakes and 528 added.

The largest buyer was Two Sigma Advisers, opening a new position worth an estimated $381M. The largest seller was JP Morgan Chase, cutting an estimated $964M.

  • 1,291 institutional investors held Regeneron Pharmaceuticals (REGN) as of Q1 2025, down from 1,318 in Q4 2024.
  • Funds reported $59.1B of Regeneron Pharmaceuticals stock for Q1 2025, down 11% quarter-over-quarter.
  • 139 funds opened new Regeneron Pharmaceuticals positions in Q1 2025 and 147 closed out, a net change of -8 holders.
  • The largest Regeneron Pharmaceuticals buyer in Q1 2025 was Two Sigma Advisers, an estimated $381M added.
  • The largest Regeneron Pharmaceuticals seller in Q1 2025 was JP Morgan Chase, an estimated $964M sold.

Based on aggregated 13F filings for Q1 2025.