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Regeneron Pharmaceuticals

1,202 hedge funds and large institutions have $46.9B invested in Regeneron Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 132 funds opening new positions, 444 increasing their positions, 477 reducing their positions, and 206 closing their positions.

New
Increased
Maintained
Reduced
Closed

14% more call options, than puts

Call options by funds: $1.15B | Put options by funds: $1.01B

7% less repeat investments, than reductions

Existing positions increased: 444 | Existing positions reduced: 477

2.66% less ownership

Funds ownership: 86.78%84.12% (-2.7%)

7% less funds holding

Funds holding: 1,2901,202 (-88)

20% less funds holding in top 10

Funds holding in top 10: 1512 (-3)

21% less capital invested

Capital invested by funds: $59.1B → $46.9B (-$12.2B)

36% less first-time investments, than exits

New positions opened: 132 | Existing positions closed: 206

Holders
1,202
Holders Change
-88
Holders Change %
-6.82%
% of All Funds
15.83%
Holding in Top 10
12
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-20%
% of All Funds
0.16%
New
132
Increased
444
Reduced
477
Closed
206
Calls
$1.15B
Puts
$1.01B
Net Calls
+$139M
Net Calls Change
+$166M
Name Holding Trade Value Shares
Change
Change in
Stake
HI
301
Horizon Investments
North Carolina
$6.95M +$6.48M +11,608 +710%
Janus Henderson Group
302
Janus Henderson Group
United Kingdom
$6.87M -$260K -465 -3%
PA
303
Profund Advisors
Maryland
$6.78M +$775K +1,388 +12%
GCA
304
Greenwood Capital Associates
South Carolina
$6.75M +$2.47M +4,419 +52%
GAM
305
Generali Asset Management
Italy
$6.66M +$921K +1,650 +15%
HT
306
Headlands Technologies
Illinois
$6.64M +$5.17M +9,259 +273%
AIM
307
ARK Investment Management
Florida
$6.62M -$607K -1,088 -8%
RAM
308
RK Asset Management
Michigan
$6.62M +$21.8K +39 +0.3%
Janney Montgomery Scott
309
Janney Montgomery Scott
Pennsylvania
$6.61M -$8.62M -15,452 -55%
SC
310
Slow Capital
California
$6.51M -$3.95M -7,071 -36%
Calamos Advisors
311
Calamos Advisors
Illinois
$6.44M
NAM
312
NorthCrest Asset Manangement
Minnesota
$6.32M -$195K -349 -3%
GIM
313
Generate Investment Management
New Zealand
$6.3M +$6.7M +12,000 New
HCM
314
Harvey Capital Management
Florida
$6.28M -$753K -1,350 -10%
TI
315
Trexquant Investment
Connecticut
$6.27M -$25.1M -44,995 -79%
MOACM
316
Mutual of America Capital Management
New York
$6.24M -$182K -326 -3%
ClearBridge Investments
317
ClearBridge Investments
New York
$6.22M +$2.86M +5,121 +76%
AI
318
Atria Investments
North Carolina
$6.02M +$805K +1,442 +14%
MPM
319
Meritage Portfolio Management
Kansas
$6.01M +$6.39M +11,455 New
MWM
320
Marietta Wealth Management
Georgia
$6.01M +$376K +673 +6%
ACA
321
Anchor Capital Advisors
Massachusetts
$5.97M +$209K +375 +3%
OAM
322
OP Asset Management
$5.96M -$198K -354 -3%
RSCM
323
Rock Springs Capital Management
Maryland
$5.93M +$4.74M +8,500 +304%
SLAM
324
Swiss Life Asset Management
$5.86M +$421K +754 +7%
TSW
325
Thompson Siegel & Walmsley
Virginia
$5.82M +$564K +1,010 +10%

REGN Hedge Fund Activity: Q2 2025 in Review

1,202 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Regeneron Pharmaceuticals (REGN) for Q2 2025, worth a combined $46.9B — down 21% from $59.1B a quarter earlier.

Sellers outnumbered buyers: 206 funds closed out of REGN and 132 opened new positions — a net loss of 74 holders — while 477 trimmed existing stakes and 444 added.

The largest buyer was Dodge & Cox, adding an estimated $838M. The largest seller was Fidelity Investments, cutting an estimated $2.38B.

  • 1,202 institutional investors held Regeneron Pharmaceuticals (REGN) as of Q2 2025, down from 1,290 in Q1 2025.
  • Funds reported $46.9B of Regeneron Pharmaceuticals stock for Q2 2025, down 21% quarter-over-quarter.
  • 132 funds opened new Regeneron Pharmaceuticals positions in Q2 2025 and 206 closed out, a net change of -74 holders.
  • The largest Regeneron Pharmaceuticals buyer in Q2 2025 was Dodge & Cox, an estimated $838M added.
  • The largest Regeneron Pharmaceuticals seller in Q2 2025 was Fidelity Investments, an estimated $2.38B sold.

Based on aggregated 13F filings for Q2 2025.