Pulse Biosciences
PLSE
82 hedge funds and large institutions have $86.9M invested in Pulse Biosciences in 2025 Q4 according to their latest regulatory filings, with 11 funds opening new positions, 24 increasing their positions, 27 reducing their positions, and 13 closing their positions.
94% more call options, than puts
Call options by funds: $500K | Put options by funds: $258K
0.64% more ownership
Funds ownership: 8.69% → 9.33% (+0.64%)
2% less funds holding
Funds holding: 84 → 82 (-2)
11% less repeat investments, than reductions
Existing positions increased: 24 | Existing positions reduced: 27
15% less first-time investments, than exits
New positions opened: 11 | Existing positions closed: 13
16% less capital invested
Capital invested by funds: $104M → $86.9M (-$16.6M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
PCM
Portolan Capital Management
Boston,
Massachusetts
|
+$4.54M |
| 2 |
BIG
Brooklyn Investment Group
Brooklyn,
New York
|
+$2.03M |
| 3 |
BlackRock
New York
|
+$765K |
| 4 |
Tudor Investment Corp
Stamford,
Connecticut
|
+$433K |
| 5 |
State Street
Boston,
Massachusetts
|
+$392K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Jane Street
New York
|
-$604K |
| 2 |
Royal Bank of Canada
Toronto,
Ontario, Canada
|
-$538K |
| 3 |
SO
STRS Ohio
Columbus,
Ohio
|
-$340K |
| 4 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
-$256K |
| 5 |
LPL Financial
San Diego,
California
|
-$218K |
PLSE Hedge Fund Activity: Q4 2025 in Review
82 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Pulse Biosciences (PLSE) for Q4 2025, worth a combined $86.9M — down 16% from $104M a quarter earlier.
Sellers outnumbered buyers: 13 funds closed out of PLSE and 11 opened new positions — a net loss of 2 holders — while 27 trimmed existing stakes and 24 added.
The largest buyer was Portolan Capital Management, adding an estimated $4.54M. The largest seller was Jane Street, exiting entirely with an estimated $604K sold.
- 82 institutional investors held Pulse Biosciences (PLSE) as of Q4 2025, down from 84 in Q3 2025.
- Funds reported $86.9M of Pulse Biosciences stock for Q4 2025, down 16% quarter-over-quarter.
- 11 funds opened new Pulse Biosciences positions in Q4 2025 and 13 closed out, a net change of -2 holders.
- The largest Pulse Biosciences buyer in Q4 2025 was Portolan Capital Management, an estimated $4.54M added.
- The largest Pulse Biosciences seller in Q4 2025 was Jane Street, an estimated $604K sold.
Based on aggregated 13F filings for Q4 2025.