2,847 hedge funds and large institutions have $92.3B invested in Pfizer in 2025 Q4 according to their latest regulatory filings, with 294 funds opening new positions, 1,065 increasing their positions, 1,252 reducing their positions, and 167 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

more ownership

Funds ownership:

less capital invested

Capital invested by funds: $ → $

15% less funds holding in top 10

Funds holding in top 10: 3429 (-5)

15% less repeat investments, than reductions

Existing positions increased: 1,065 | Existing positions reduced: 1,252

19% less call options, than puts

Call options by funds: $2.58B | Put options by funds: $3.18B

Holders
2,847
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
29
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.58B
Puts
$3.18B
Net Calls
Net Calls Change

Top Buyers

1 +$362M
2 +$342M
3 +$189M
4
Capital World Investors
Capital World Investors
California
+$184M
5
Goldman Sachs
Goldman Sachs
New York
+$182M

Top Sellers

1 -$450M
2 -$223M
3 -$211M
4
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
-$167M
5
Jane Street
Jane Street
New York
-$146M
Name Holding Trade Value Shares
Change
Change in
Stake
ISS
201
Intesa Sanpaolo SpA.
Italy
$43M
WIC
202
Willis Investment Counsel
Georgia
$42.7M
KAS
203
Kestra Advisory Services
Texas
$42.5M
QCM
204
Quantinno Capital Management
New York
$41.8M
SOMRS
205
State of Michigan Retirement System
Michigan
$41.6M
BS
206
Banco Santander
Spain
$41.4M
O
207
OrbiMed
New York
$41.2M
CAI
208
Capital Advisors Inc
Oklahoma
$40.9M
WP
209
Woodline Partners
California
$40.5M
Carson Wealth (CWM LLC)
210
Carson Wealth (CWM LLC)
Nebraska
$40.5M
ASRS
211
Arizona State Retirement System
Arizona
$39.8M
CIBC Asset Management
212
CIBC Asset Management
Ontario, Canada
$39.5M
AH
213
Allen Holding
New York
$37.8M
CB
214
Commerce Bank
Missouri
$37.8M
CNB
215
Czech National Bank
Czech Republic
$37.3M
Nisa Investment Advisors
216
Nisa Investment Advisors
Missouri
$37.2M
Simplex Trading
217
Simplex Trading
Illinois
$37.1M
ECM
218
ExodusPoint Capital Management
New York
$36.9M
AWM
219
AE Wealth Management
Kansas
$36.2M
Los Angeles Capital Management
220
Los Angeles Capital Management
California
$35.7M
SP
221
Sarasin & Partners
United Kingdom
$35.2M
KeyBank National Association
222
KeyBank National Association
Ohio
$35.1M
Mirae Asset Global ETFs Holdings
223
Mirae Asset Global ETFs Holdings
Hong Kong
$35M
William Blair & Company
224
William Blair & Company
Illinois
$34.4M
MML Investors Services
225
MML Investors Services
Massachusetts
$34.4M